scholarly journals Effect of Magnetic Resonance Imaging on Breast Conservation Therapy versus Mastectomy: A Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Thomas J. Painter ◽  
Peter J. DiPasco ◽  
Subhasis Misra ◽  
Eli Avisar

The utilization of MRI in the workup of breast cancer has played a controversial role in the surgical treatment of this disease. With the higher resolution of breast tissue afforded, additional lesions are being identified that often warrant additional procedures, subsequently affecting the decision to proceed with breast conservation therapy versus mastectomy. In this paper, a literature review is presented to help illuminate some of the benefits and pitfalls of employing MRI as a diagnostic tool in the care of breast cancer, while additionally providing insight into the management alterations this imaging modality can engender. Though further research is required in a randomized prospective form to fully answer this question, evidence for and against its use continues to mount, especially for select patient groups.

Reports ◽  
2020 ◽  
Vol 3 (3) ◽  
pp. 18
Author(s):  
Andriani D. Vouxinou ◽  
Georgios M. Iatrakis ◽  
Stefanos Zervoudis ◽  
Anastasia Bothou ◽  
Sofia Tsitsiou ◽  
...  

Both benign and malignant conditions related to regional or systemic disorders could be included in the differential diagnosis of bilateral breast edema. Some of them are often unilateral, including stromal infiltration and lymphatic obstruction presented in “peau d’ orange”, which is the usual presentation of breast cancer. However, the term “idiopathic” could be included in the spectrum of diagnoses. Here, we present a woman of 78 years old who came into our breast unit with a bilateral, painless edema of the breasts (appeared one month ago). Clinical examination revealed that both breasts were swollen with widespread erythema and the appearance of an orange peel/“peau d’ orange”. On palpation, the breasts were not sensitive, and no tumor was palpable. However, clinically palpable lymph nodes were found in both axillas. Her temperature was normal. The breast edema could not be explained from her medical history nor the medications taken. Breast ultrasound, Mammography and Magnetic Resonance Imaging were non-conclusive (BI-RADS 0) and bilateral core biopsy was negative for cancer. Anti-inflammatory plus antibiotic therapy was prescribed for 10 days and at the end of treatment, regional redness and edema were disappeared and reduced, respectively. Total recovery was found one month after the initial findings. It can be concluded that bilateral breast edema is correlated to regional or systemic conditions or it is presented as an “idiopathic” disorder of unknown etiology.


2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
M Davenport ◽  
R Okhiria ◽  
E Barrett ◽  
L Highton

Abstract Introduction Magnetic Resonance Imaging (MRI) is used to assess the response to Neoadjuvant Chemotherapy (NAC) when used in patients with breast cancer. Method This retrospective observational study compared patterns of tumour response at mid-chemotherapy and post-chemotherapy MRIs to histological outcomes. 118 cases of breast cancer, from a local database, were included. Results There was a significant association between complete pathological response in resected breast tissue and complete radiological response on both mid-chemotherapy MRI (p = 0.007) and post-chemotherapy MRI (p < 0.001). In patients who had both scans,100% of those with complete response at mid-chemotherapy scan maintained this response pattern. In those who had both scans, complete response at the mid-chemotherapy scan had a PPV for complete pathological response in resected breast tissue of 92% compared to 64% in those with complete response that was not achieved until the post-chemotherapy scan. There was a trend towards an association between early complete radiological response and complete pathological response (p = 0.124). Conclusions Both scans have significant prognostic value. A mid-chemotherapy scan may have superior prognostic value when complete response is achieved, though larger studies are needed to determine the significance. 100% maintenance of complete radiological response after the mid-chemotherapy scan highlights the possibility that some post-chemotherapy scan could be avoided.


2020 ◽  
Vol 13 (6) ◽  
pp. 229-240
Author(s):  
Nagaraja Pullaiah ◽  
◽  
Dorai Venkatasekhar ◽  
Padarthi Venkatramana ◽  
Balaraj Sudhakar ◽  
...  

Breast cancer is one of the most occurring cancers in women due to the uncontrolled growth of abnormal cells in the lobules or milk ducts. The treatment for the breast cancer at an early stage is important using Magnetic Resonance Imaging (MRI) which effectively measures the size of the cancer and also checks tumors in the opposite breast. The deposition of calcium components on the breast tissue is known as micro-calcifications. The calcium salts deposited in the breast are involved with the cancer and were not diagnosed accurately due to the low effectiveness of existing imaging technique namely Haralick feature extraction technique. The MRI breast cancer diagnosis creates problems during classification of breast image and leads to misclassifications, such as unidentified calcium deposits in the existing K-Nearest Neighbour (KNN) classifier. The misclassification issues are overcome by an accurate classification and identification of calcium salts and checks whether deposited salt on breast tissue is involved with cancer or not. Initially, Contrast-Limited Adaptive Histogram Equalization (CLAHE) is used to remove the unwanted noise in the MRI and Morphological, Multilevel Otsu’s Thresholding and region growing techniques perform segmentation to mask unwanted breast tissues. The proposed Hybrid LOOP Haralick feature extraction technique is developed by combining the both Local Optimal Oriented Pattern (LOOP) and Haralick texture feature and the hybrid parameters are applied to the Stacked Auto Encoder based (SAE) to classify the breast MRI image as a Malignant or Benign. The performance of the proposed hybrid LOOP Haralick feature extraction shows significant accuracy improvement of 3.83% when compared to the Haralick feature extraction technique.


2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
L. Losurdo ◽  
T. M. A. Basile ◽  
A. Fanizzi ◽  
R. Bellotti ◽  
U. Bottigli ◽  
...  

Breast cancer is the main cause of female malignancy worldwide. Effective early detection by imaging studies remains critical to decrease mortality rates, particularly in women at high risk for developing breast cancer. Breast Magnetic Resonance Imaging (MRI) is a common diagnostic tool in the management of breast diseases, especially for high-risk women. However, during this examination, both normal and abnormal breast tissues enhance after contrast material administration. Specifically, the normal breast tissue enhancement is known as background parenchymal enhancement: it may represent breast activity and depends on several factors, varying in degree and distribution in different patients as well as in the same patient over time. While a light degree of normal breast tissue enhancement generally causes no interpretative difficulties, a higher degree may cause difficulty to detect and classify breast lesions at Magnetic Resonance Imaging even for experienced radiologists. In this work, we intend to investigate the exploitation of some statistical measurements to automatically characterize the enhancement trend of the whole breast area in both normal and abnormal tissues independently from the presence of a background parenchymal enhancement thus to provide a diagnostic support tool for radiologists in the MRI analysis.


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