scholarly journals Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes Mellitus

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Shridhar N. Iyer ◽  
Almond J. Drake ◽  
R. Lee West ◽  
Robert J. Tanenberg

Objective. To report a case of diabetic muscle infarction (DMI), a rare complication of long-standing poorly controlled diabetes mellitus.Methods. We describe a case of a 45-year-old male with an approximately 8-year history of poorly controlled type 2 diabetes mellitus with multiple microvascular complications who presented with the sudden onset of left thigh pain and swelling. He had a swollen left thigh and a CK of 1670 U/L. He was initially treated with intravenous antibiotics for a presumptive diagnosis of pyomyositis or necrotizing fasciitis with no improvement. A diagnosis of diabetic muscle infarction was considered.Results. An MRI of the thigh demonstrated diffuse edema in the anterior compartment. A muscle biopsy demonstrated coagulation necrosis in skeletal muscle and inflammation and infarction in the walls of small blood vessels. These studies confirmed the final diagnosis of DMI. He was treated with supportive care and gradually improved.Conclusion. DMI is a rare complication of diabetes that is often mistaken for infections such as pyomyositis and necrotizing fasciitis or thrombophlebitis. Treatment is supportive. Although the short-term prognosis is good in these patients, the long-term prognosis is poor.

2018 ◽  
Vol 8 (3) ◽  
pp. 263-265
Author(s):  
Muhammad Saiful Islam ◽  
Rafi Nazrul Islam ◽  
Mohammad Sakhawat Hossen Khan ◽  
Wasim Md Mohosin Ul Haque ◽  
Mohammad Ashraful Islam

We report a case of sudden left thigh pain in adductor muscles of medial compartment, known as diabetic myonecrosis, in a 50-year-old patient with poorly controlled diabetes mellitus. Diabetic muscle infarction is a rare end-organ complication seen in patients with poor glycemic control and advanced chronic microvascular complications. Proposed mechanisms involve atherosclerotic microvascular occlusion, ischemia-reperfusion related injury, vasculitis with microthrombi formation, and an acquired antiphospholipid syndrome. The clinical presentation is swelling, pain, and tenderness of the involved muscle, most commonly the thigh muscles. Management consists of conservative measures including analgesia and rest.Birdem Med J 2018; 8(3): 263-265


2016 ◽  
Vol 10 ◽  
Author(s):  
Marianna Gregorio ◽  
Antonio Villa

We report a case of necrotizing fasciitis in an 84 year-old man affected by diabetes mellitus. The patient was admitted in the Emergency Department of our hospital because of an acute and strong left leg pain that began almost 8 hours before admission. The left leg had an increased size and a movement limitation, with a hard haemathoma in the left thigh with subcutaneous crepitus. The lesion became worse and larger rapidly, with a wide extension from the back to the popliteal fossa. An antimicrobial therapy was immediately started with morphine for pain. A surgical debridment was performed, but the patient died for multiorgan failure. Necrotizing fasciitis is a rare and mortal disease, the early diagnosis is a challenge for the Emergency Department where patients are admitted and assessed primarly.


2007 ◽  
Vol 15 (1) ◽  
pp. 61-65 ◽  
Author(s):  
Sarah R. Glauser ◽  
Jonathan Glauser ◽  
Stephen F. Hatem

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Yang Chen ◽  
Hui Dong ◽  
Xiongjing Jiang ◽  
Wuqiang Che

Abstract Background Renal artery intramural haematoma (IMH) is a rare cause of renal artery obstruction after stenting. Diagnosis and treatment are difficult as there are only a few cases reported. Case summary We present the case of sudden-onset abdominal pain and non-functional kidney 3 days after renal artery stent implantation. Subacute luminal narrowing of the renal artery was initially diagnosed using computed tomography angiography and renal artery angiography, and a final diagnosis of subacute renal artery IMH was made using intravascular ultrasound (IVUS). Subsequently, the patient was treated with percutaneous transluminal angioplasty from far to near and another stent implantation. At the third month follow-up, blood pressure and renal function were normal. Discussion This case suggests that IVUS could be useful for qualifying and treating the subacute renal artery IMH.


2019 ◽  
Vol 9 (1) ◽  
pp. 53-58
Author(s):  
Shaza Ahmed Samargandy ◽  
Amani M. Alhozali

Diabetes mellitus is a multifaceted metabolic disease with several serious complications. Diabetic muscle infarction is a rare musculoskeletal diabetic complication that can be frequently misdiagnosed as it shares clinical manifestations with multiple other more common clinical disorders. We present in this report, a case of diabetic myonecrosis with brief discussion about this unusual complication along with its management and expected outcomes.


2005 ◽  
Vol 53 (1) ◽  
pp. S255.3-S255
Author(s):  
K. E. Ashley ◽  
J. Frost ◽  
S. Sanders ◽  
K. Kirchner ◽  
Sonny G.V. Montgomery

2014 ◽  
Vol 53 (18) ◽  
pp. 2091-2094 ◽  
Author(s):  
Wafa Chebbi ◽  
Saida Jerbi ◽  
Rym Klii ◽  
Wafa Alaya ◽  
Sarra Mestiri ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Sisira Sran ◽  
Manpreet Sran ◽  
Nicole Ferguson ◽  
Prachi Anand

We report a case of sudden thigh pain from spontaneous quadriceps necrosis, also known as diabetic myonecrosis, in a 28-year-old patient with poorly controlled diabetes mellitus. Diabetic muscle infarction is a rare end-organ complication seen in patients with poor glycemic control and advanced chronic microvascular complications. Proposed mechanisms involve atherosclerotic microvascular occlusion, ischemia-reperfusion related injury, vasculitis with microthrombi formation, and an acquired antiphospholipid syndrome. Diabetic myonecrosis most commonly presents as sudden thigh pain with swelling and should be considered in any patient who has poorly controlled diabetes mellitus.


2019 ◽  
Vol 7 ◽  
pp. 2050313X1882346
Author(s):  
Rami Alkhoury

Diabetes mellitus is a growing concern in today’s population and a common cause of significant morbidity and mortality in those affected. Diabetic myonecrosis is an uncommon condition that can be seen in uncontrolled, long-standing diabetic patients who complain of localized, sudden-onset muscle pain. We present a 57-year-old woman with type 2 diabetes mellitus who presented to the emergency department with left-sided pelvic pain for the past 2 months. The pain had progressively gotten worse with a significant reduction in the range of motion of her left hip. Magnetic resonance imaging imaging revealed focal enhancement, edema, and enlargement of the left iliacus muscle. Assessment of serum glucose and hemoglobin A1c revealed a history of poor diabetic control, eventually giving rise to a diagnosis of diabetic myonecrosis. She was discharged with a new diabetic regimen, pain control, and outpatient physical therapy.


2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Roopam Jariwal ◽  
Nadia Raza ◽  
Catherine Cadang ◽  
Syed Rahman ◽  
David Contreras ◽  
...  

Diabetic muscle infarction (DMI) is a rare complication of poorly controlled type 1 and type 2 diabetes seen mostly in those who have already experienced microvascular complications. Currently, the incidence and prevalence of DMI are difficult to conclude, and there is no clear algorithm or standard of care in managing this condition. Pathogenesis of the microangiopathy of DMI remains unclear. A major finding in this investigation of DMI emphasizes that, within 2–17 weeks, patients who initiate low-dose acetylsalicylic acid, bed rest, and close outpatient follow-up see significant size reduction of lower extremity mass and complete resolution of pain without being subjected to invasive muscle biopsy.


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