scholarly journals Chondrosarcoma of the Mobile Spine and Sacrum

Sarcoma ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Ryan M. Stuckey ◽  
Rex A. W. Marco
Keyword(s):  
Local Recurrence ◽  
Malignant Tumors ◽  
Chemotherapy Treatment ◽  
Recurrence Rates ◽  
En Bloc ◽  
Mobile Spine ◽  
En Bloc Excision ◽  
Bloc Excision ◽  
Cartilage Tumor ◽  
Tumor Pain

Chondrosarcoma is a rare malignant tumor of bone. This family of tumors can be primary malignant tumors or a secondary malignant transformation of an underlying benign cartilage tumor. Pain is often the initial presenting complaint when chondrosarcoma involves the spine. In the mobile spine, chondrosarcoma commonly presents within the vertebral body and shows a predilection for the thoracic spine. Due to the resistance of chondrosarcoma to both radiation and chemotherapy, treatment is focused on surgery. With en bloc excision of chondrosarcoma of the mobile spine and sacrum patients can have local recurrence rates as low as 20%.

Surgical management of primary and metastatic sarcoma of the mobile spine

2008 ◽  
Vol 9 (2) ◽  
pp. 120-128 ◽  
Author(s):  
Ganesh Rao ◽  
Dima Suki ◽  
Indro Chakrabarti ◽  
Iman Feiz-Erfan ◽  
Milan G. Mody ◽  
...  
Keyword(s):  
Overall Survival ◽  
Local Recurrence ◽  
Median Survival ◽  
Neurological Function ◽  
High Grade ◽  
Recurrence Rates ◽  
En Bloc ◽  
Study Results ◽  
Mobile Spine ◽  
Metastatic Sarcoma

Object Sarcomas of the spine are a challenging problem due to their frequent and extensive involvement of multiple spinal segments and high recurrence rates. Gross-total resection to negative margins, with preservation of neurological function and palliation of pain, is the surgical goal and may be achieved using either intralesional resection or en bloc excision. The authors report outcomes of surgery for primary and metastatic sarcomas of the mobile spine in a large patient series. Methods A retrospective review of patients undergoing resection for sarcomas of the mobile spine between 1993 and 2005 was undertaken. Sarcomas were classified by histology study results and as either primary or metastatic. Details of the surgical approach, levels of involvement, and operative complications were recorded. Outcome measures included neurological function, palliation of pain, local recurrence, and overall survival. Results Eighty patients underwent 110 resections of either primary or metastatic sarcomas of the mobile spine. Twenty-nine lesions were primary sarcomas (36%) and 51 were metastatic sarcomas (64%). Intralesional resections were performed in 98 surgeries (89%) and en bloc resections were performed in 12 (11%). Median survival from surgery for all patients was 20.6 months. Median survival for patients with a primary sarcoma of the spine was 40.2 months and was 17.3 months for patients with a metastatic sarcoma. Predictors of improved survival included a chondrosarcoma histological type and a better preoperative functional status, whereas osteosarcoma and a high-grade tumor were negative influences on survival. Multivariate analysis showed that only a high-grade tumor was an independent predictor of shorter overall survival. American Spinal Injury Association scale grades were maintained or improved in 97% of patients postoperatively, and there was a significant decrease in pain scores postoperatively. No significant differences in survival or local recurrence rates between intralesional or en bloc resections for either primary or metastatic spine sarcomas were found. Conclusions Surgery for primary or metastatic sarcoma of the spine is associated with an improvement in neurological function and palliation of pain. The results of this study show a significant difference in patient survival for primary versus metastatic spine sarcomas. The results do not show a statistically significant benefit in survival or local recurrence rates for en bloc versus intralesional resections for either metastatic or primary sarcomas of the spine, but this may be due to the small number of patients undergoing en bloc resections.

En Bloc Excision in Malignant Tumors of the Lacrimal Drainage Apparatus

2006 ◽  
Vol 22 (5) ◽  
pp. 356-360 ◽  
Author(s):  
Alejandra A. Valenzuela ◽  
Dinesh Selva ◽  
Alan A. McNab ◽  
Guy B. Simon ◽  
Timothy J. Sullivan
Keyword(s):  
Malignant Tumors ◽  
En Bloc ◽  
En Bloc Excision ◽  
Bloc Excision ◽  
Lacrimal Drainage

En Bloc Excision of Proximal Nail Fold for Treatment of Chronic Paronychia

2006 ◽  
Vol 32 (3) ◽  
pp. 393-399
Author(s):  
CHANDER GROVER ◽  
SHIKHA BANSAL ◽  
SONI NANDA ◽  
BSN. REDDY ◽  
VIJAY KUMAR
Keyword(s):  
En Bloc ◽  
En Bloc Excision ◽  
Bloc Excision

scholarly journals Mobile spine chordoma: results of 166 patients from the AOSpine Knowledge Forum Tumor database

2016 ◽  
Vol 24 (4) ◽  
pp. 644-651 ◽  
Author(s):  
Ziya L. Gokaslan ◽  
Patricia L. Zadnik ◽  
Daniel M. Sciubba ◽  
Niccole Germscheid ◽  
C. Rory Goodwin ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Survival Data ◽  
Large Scale ◽  
Surgical Techniques ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc ◽  
Increased Risk ◽  
Significant Difference ◽  
Mobile Spine

OBJECT A chordoma is an indolent primary spinal tumor that has devastating effects on the patient's life. These lesions are chemoresistant, resistant to conventional radiotherapy, and moderately sensitive to proton therapy; however, en bloc resection remains the preferred treatment for optimizing patient outcomes. While multiple small and largely retrospective studies have investigated the outcomes following en bloc resection of chordomas in the sacrum, there have been few large-scale studies on patients with chordomas of the mobile spine. The goal of this study was to review the outcomes of surgically treated patients with mobile spine chordomas at multiple international centers with respect to local recurrence and survival. This multiinstitutional retrospective study collected data between 1988 and 2012 about prognosis-predicting factors, including various clinical characteristics and surgical techniques for mobile spine chordoma. Tumors were classified according to the Enneking principles and analyzed in 2 treatment cohorts: Enneking-appropriate (EA) and Enneking-inappropriate (EI) cohorts. Patients were categorized as EA when the final pathological assessment of the margin matched the Enneking recommendation; otherwise, they were categorized as EI. METHODS Descriptive statistics were used to summarize the data (Student t-test, chi-square, and Fisher exact tests). Recurrence and survival data were analyzed using Kaplan-Meier survival curves, log-rank tests, and multivariate Cox proportional hazard modeling. RESULTS A total of 166 patients (55 female and 111 male patients) with mobile spine chordoma were included. The median patient follow-up was 2.6 years (range 1 day to 22.5 years). Fifty-eight (41%) patients were EA and 84 (59%) patients were EI. The type of biopsy (p < 0.001), spinal location (p = 0.018), and if the patient received adjuvant therapy (p < 0.001) were significantly different between the 2 cohorts. Overall, 58 (35%) patients developed local recurrence and 57 (34%) patients died. Median survival was 7.0 years postoperative: 8.4 years postoperative for EA patients and 6.4 years postoperative for EI patients (p = 0.023). The multivariate analysis showed that the EI cohort was significantly associated with an increased risk of local recurrence in comparison with the EA cohort (HR 7.02; 95% CI 2.96–16.6; p < 0.001), although no significant difference in survival was observed. CONCLUSIONS EA resection plays a major role in decreasing the risk for local recurrence in patients with chordoma of the mobile spine.

scholarly journals Two-staged en bloc excision of a retinal haemangioma

2017 ◽  
pp. bcr-2017-220216
Author(s):  
Mahima Jhingan ◽  
Jay Chhablani ◽  
Komal Agarwal ◽  
Padmaja Kumari Rani
Keyword(s):  
En Bloc ◽  
En Bloc Excision ◽  
Bloc Excision

En bloc excision of a dermal sinus tract

2011 ◽  
Vol 18 (4) ◽  
pp. 554-558 ◽  
Author(s):  
Jean-Valery Coumans ◽  
Brian P. Walcott ◽  
Navid Redjal ◽  
Kristopher T. Kahle ◽  
Brian V. Nahed
Keyword(s):  
Sinus Tract ◽  
Dermal Sinus ◽  
En Bloc ◽  
Dermal Sinus Tract ◽  
En Bloc Excision ◽  
Bloc Excision

Unusual gastric tumour in an adolescent: primary gastric teratoma

2020 ◽  
Vol 13 (12) ◽  
pp. e236858
Author(s):  
Rahul Kumar ◽  
Tripti Prajapati ◽  
Rahul Verma ◽  
Pankaj Kumar Garg
Keyword(s):  
Wedge Resection ◽  
Abdominal Mass ◽  
En Bloc ◽  
Curative Intent ◽  
Gastric Teratoma ◽  
Gastric Tumour ◽  
Abdominal Masses ◽  
En Bloc Excision ◽  
Bloc Excision ◽  
High Index Of Suspicion

Gastric teratoma is a rare entity beyond infancy and usually presents as a slow-growing asymptomatic abdominal mass. There are a few published reports of these tumours seen in patients beyond the age of 1 year. In resource-constrained population, these masses are usually neglected because of minimal symptoms associated with these tumours. We report a case of a 14-year-old adolescent who was diagnosed to have a large primary gastric teratoma and underwent en bloc excision with wedge resection of the stomach. A systematic review to identify the previously reported cases of primary gastric teratoma in patients of over the age of 1 year in last 50 years yielded only five articles. A high index of suspicion for primary gastric teratomas in young children and adolescents presenting with asymptomatic large abdominal masses would help treat these patients with a curative intent and excellent treatment outcomes.

Sign in / Sign up

Export Citation Format

Share Document