scholarly journals Erratum to “Protein Profiling of Human Nonpigmented Ciliary Epithelium Cell Secretome: The Differentiation Factors Characterization for Retinal Ganglion Cell Line”

2011 ◽  
Vol 2011 ◽  
pp. 1-1
Author(s):  
Ming-Hui Yang ◽  
Raghu R. Krishnamoorthy ◽  
Shiang-Bin Jong ◽  
Pei-Yu Chu ◽  
Yuan-Han Yang ◽  
...  
2011 ◽  
Vol 2011 ◽  
pp. 1-28 ◽  
Author(s):  
Ming-Hui Yang ◽  
Raghu R. Krishnamoorthy ◽  
Shiang-Bin Jong ◽  
Pei-Yu Chu ◽  
Yuan-Han Yang ◽  
...  

The purpose of this paper was to characterize proteins secreted from the human nonpigmented ciliary epithelial (HNPE) cells, which have differentiated a rat retinal ganglion cell line, RGC-5. Undifferentiated RGC-5 cells have been shown to express several marker proteins characteristic of retinal ganglion cells. However, RGC-5 cells do not respond to N-methyl-D aspartate (NMDA), or glutamate. HNPE cells have been shown to secrete numbers of neuropeptides or neuroproteins also found in the aqueous humor, many of which have the ability to influence the activity of neuronal cells. This paper details the profile of HNPE cell-secreted proteins by proteomic approaches. The experimental results revealed the identification of 132 unique proteins from the HNPE cell-conditioned SF-medium. The biological functions of a portion of these identified proteins are involved in cell differentiation. We hypothesized that a differentiation system of HNPE cell-conditioned SF-medium with RGC-5 cells can induce a differentiated phenotype in RGC-5 cells, with functional characteristics that more closely resemble primary cultures of rat retinal ganglion cells. These proteins may replace harsh chemicals, which are currently used to induce cell differentiation.


2009 ◽  
Vol 450 (2) ◽  
pp. 163-166 ◽  
Author(s):  
Widyawilis Selamat ◽  
Ildasolha Jamari ◽  
Yu Wang ◽  
Toru Takumi ◽  
Fulton Wong ◽  
...  

2009 ◽  
Vol 50 (9) ◽  
pp. 4267 ◽  
Author(s):  
Nicole J. Van Bergen ◽  
John P. M. Wood ◽  
Glyn Chidlow ◽  
Ian A. Trounce ◽  
Robert J. Casson ◽  
...  

2006 ◽  
Vol 1086 (1) ◽  
pp. 191-200 ◽  
Author(s):  
Ashish Agar ◽  
Shaojuan Li ◽  
Neeraj Agarwal ◽  
Minas T. Coroneo ◽  
Mark A. Hill

2004 ◽  
Vol 1003 (1-2) ◽  
pp. 205-208 ◽  
Author(s):  
Andrew J. Moorhouse ◽  
Shaojuan Li ◽  
Richard M. Vickery ◽  
Mark A. Hill ◽  
John W. Morley

Peptides ◽  
2012 ◽  
Vol 36 (2) ◽  
pp. 280-285 ◽  
Author(s):  
Yong Ding ◽  
Huanhuan Cheng ◽  
Rongjie Yu ◽  
Cuicui Tang ◽  
Xiaofei Liu ◽  
...  

2010 ◽  
Vol 57 (3) ◽  
pp. 216-226 ◽  
Author(s):  
Paula S. Nieto ◽  
Victoria A. Acosta-Rodríguez ◽  
Diego J. Valdez ◽  
Mario E. Guido

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