scholarly journals Malignant Cerebral Edema following CT Myelogram Using Isovue-M 300 Intrathecal Nonionic Water-Soluble Contrast: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-6
Author(s):  
Brian C. Kelley ◽  
Simon Roh ◽  
Philip L. Johnson ◽  
Paul M. Arnold
Keyword(s):  
Case Report ◽  
Contrast Medium ◽  
Current Literature ◽  
Cerebral Edema ◽  
Intrathecal Injection ◽  
Water Soluble ◽  
Complication Rates ◽  
Nonionic Contrast Medium ◽  
Ionic Contrast ◽  
Water Soluble Contrast

Lumbar myelogram utilizing nonionic contrast is a commonly performed procedure to identify spinal pathology. Complication rates are low. Cerebral edema has been shown to occur following intrathecal injection of ionic contrast; however, no current literature has documented this complication relating to the ubiquitously used nonionic contrast medium. We report a case of a patient who developed malignant cerebral edema following a lumbar myelogram with Isovue-M 300 nonionic water-soluble intrathecal contrast. We believe this is the first reported case of cerebral edema resulting from the use of a nonionic contrast.

Early Encephalic Toxicity after Inadvertent Intrathecal Injection of Low Osmolar Contrast Medium

2012 ◽  
Vol 25 (2) ◽  
pp. 222-224 ◽  
Author(s):  
L. Lonjaret ◽  
T. Geeraerts ◽  
J-F. Albucher ◽  
E. Dugert ◽  
M. Gigaud ◽  
...  
Keyword(s):  
Contrast Medium ◽  
Intrathecal Injection ◽  
Intrathecal Administration ◽  
Clonic Seizure ◽  
Water Soluble ◽  
Low Back ◽  
Ionic Contrast ◽  
Ionic Contrast Medium ◽  
Seizure Syndrome ◽  
Nonionic Contrast Media

Only nonionic contrast media are allowed for intrathecal use because of their lower neurotoxicity. In case of inadvertent intrathecal administration of an ionic contrast medium, the typical following syndrome is called ascending tonic clonic seizure syndrome. We describe the case of a 61-year-old woman with low back pain who underwent myelography. Ioxaglate, a water-soluble ionic low osmolar contrast medium was accidentally injected intrathecally. She first presented encephalic signs of neurotoxicity, followed by opisthotonic spasms and respiratory distress. In our case, ioxaglate is a low osmolar agent, leading to early encephalic toxicity (preceding medullary signs), because of its cephalic migration. The patient was successfully treated by sedation, anticonvulsant therapy and fluid hydration. Intrathecal administration of an ionic contrast medium is clearly contraindicated. In case of inadvertent injection of a low osmolar product, encephalic signs are seen first.

scholarly journals Diagnosis of submucosal tumor by injecting a water soluble contrast medium: Development pattern and growing of tumors.

1984 ◽  
Vol 143 (4) ◽  
pp. 385-395 ◽  
Author(s):  
SHIGERU ASAKI ◽  
SHIGEAKI HATORI ◽  
TOSHIAKI NISHIMURA ◽  
AKIRA SATO ◽  
KIYOAKI HANZAWA ◽  
...  
Keyword(s):  
Contrast Medium ◽  
Submucosal Tumor ◽  
Water Soluble ◽  
Development Pattern ◽  
Medium Development ◽  
Water Soluble Contrast ◽  
Water Soluble Contrast Medium

Perjodal H Viscous, a Water-Soluble Contrast Medium Containing Dextran

1956 ◽  
Vol Original Series, Volume 46 (4) ◽  
pp. 587-594
Author(s):  
F. Bergman ◽  
O. Norman ◽  
S. Sjostedt
Keyword(s):  
Contrast Medium ◽  
Water Soluble ◽  
Water Soluble Contrast ◽  
Water Soluble Contrast Medium

Severe liver injury with hematological disorders following the injection of non-ionic contrast medium: A case report

2001 ◽  
Vol 42 (3) ◽  
pp. 342-344
Author(s):  
Y. Morita ◽  
C. Kawamoto ◽  
K. Sato ◽  
T. Nakajima ◽  
Y. Kanda ◽  
...  
Keyword(s):  
Case Report ◽  
Liver Injury ◽  
Contrast Medium ◽  
Severe Liver ◽  
Hematological Disorders ◽  
Ionic Contrast ◽  
Ionic Contrast Medium
Sign in / Sign up

Export Citation Format

Share Document