scholarly journals Persistent Ureteric Dilatation due to Pelvic Actinomycosis Presenting as Pelvic Inflammatory Disease

2011 ◽  
Vol 2011 ◽  
pp. 1-2
Author(s):  
Richard Khafagy ◽  
Omar Jundi ◽  
Karol Rogawski ◽  
Siva Namasiviyam
Keyword(s):  
Renal Failure ◽  
Therapeutic Agent ◽  
Final Diagnosis ◽  
Clinical Findings ◽  
Granulomatous Disease ◽  
Filamentous Bacterium ◽  
Ureteric Obstruction ◽  
Operative Specimen ◽  
Pelvic Actinomycosis ◽  
Ureteric Dilatation

Actinomycesis a Gram-positive, filamentous bacterium that normally colonizes mucosal areas. Pelvic actinomycosis is a chronic granulomatous disease caused byActinomyces israeliithat frequently mimics ovarian tumors during presentation. It is diagnosed after surgery in most of the cases. Intravenous penicillin is the most preferred therapeutic agent, and it requires hospitalization up to one month. Pelvic actinomycosis is a rare cause of ureteric obstruction and renal failure. The final diagnosis is usually difficult and often apparent only after histological examination of an operative specimen. The present case led us to consider the etiology and clinical findings and to review the management of reported cases involving ureteric obstruction.

scholarly journals Histopathological evaluation of most frequent liver diseases in cats

2009 ◽  
Vol 63 (1-2) ◽  
pp. 103-112 ◽  
Author(s):  
Branislav Kureljusic ◽  
Darko Marinkovic ◽  
Jelena Obadovic ◽  
Milena Djordjevic ◽  
Vladimir Kukolj
Keyword(s):  
Liver Diseases ◽  
Histological Analysis ◽  
Final Diagnosis ◽  
Clinical Findings ◽  
Histological Changes ◽  
Histopathological Evaluation ◽  
Precise Diagnosis ◽  
Close Cooperation ◽  
The University ◽  
Age And Sex

Histological analysis was performed on the liver of 27 cats of different breeds, age and sex, autopsied at the Department of Pathological Morphology of the Faculty of Veterinary Medicine of the University of Belgrade, and findings showed lymphoplasmocytic cholangiohepatitis, different degrees of fibrosis, passive hyperemia, fatty changes, cholestase, and neoplasms. The mentioned entities occurred very rarely as individual morphological manifestations, because the liver has different functions so that one morphological change often causes others to follow. Thus, for example, fibrosis was often followed by intrahepatic cholestase. Histopathological evaluation of liver disease is important not only in the autopsied samples, but also in diagnostics of liver diseases, in samples obtained by biopsy, which is important for making a precise diagnosis. The interpretation of the established histological changes in the liver requires close cooperation between clinicians and pathologists, because the final diagnosis is made on the grounds of morphological, biochemical and clinical findings.

Renal Mucormycosis: A Rare Cause of Urinary Tract Infection Leading to End-stage Renal Disease (ESRD)

2018 ◽  
Vol 65 (4) ◽  
pp. 405-408
Author(s):  
Georgie Mathew ◽  
Venkatesh Arumugam ◽  
Suresh Murugesan ◽  
Neelaveni Duhli ◽  
Indira Agarwal
Keyword(s):  
Magnetic Resonance Imaging ◽  
Renal Failure ◽  
End Stage Renal Disease ◽  
Poor Prognosis ◽  
Final Diagnosis ◽  
Resonance Imaging ◽  
Course Of Illness ◽  
Stage Renal Disease ◽  
End Stage ◽  
Immunocompromised Hosts

Abstract Mucormycosis is a rare fungal infection often seen in immunocompromised hosts. Isolated renal mucormycosis may however present in immunocompetent children as renal failure and has a uniformly poor prognosis if not detected and treated early into the course of illness. We present a 3-year-old boy with unrelenting pyelonephritis in whom serial urine cultures done were negative. A final diagnosis of isolated renal mucormycosis was made by magnetic resonance imaging and renal biopsy.

Clinical Findings, Treatments and Outcomes in Farm Animals with Vertebral Fractures or Luxations: 22 Cases (2006–2017)

2019 ◽  
Vol 32 (06) ◽  
pp. 492-498 ◽  
Author(s):  
Sophie Boorman ◽  
Amy L. Johnson ◽  
Thomas P. Schaer ◽  
Marie-Eve Fecteau
Keyword(s):  
Vertebral Fracture ◽  
Neurological Examination ◽  
Clinical Signs ◽  
Final Diagnosis ◽  
Clinical Findings ◽  
Farm Animals ◽  
Cervical Region ◽  
Surgical Interventions ◽  
Cerclage Wire ◽  
Pin Fixation

Objective The aim of this study was to describe the signalment, clinical presentation, diagnostic findings, medical and surgical treatment and outcome of 22 farm animals diagnosed with a vertebral fracture or luxation. Study design Medical records of 22 farm animals (7 goats, 6 alpacas, 5 cattle, 3 sheep and 1 deer) were reviewed for signalment, history, presenting clinical signs and neurological examination findings, clinicopathological results, diagnostic imaging, final diagnosis, medical and surgical management, clinical progression and outcome. Results Animals' age ranged from 1 day to 15 years. Neurological examination findings included decreased motor function (20/22), recumbency (14/22), altered mentation (13/22), cranial nerve deficits (4/22) and lack of nociception (3/22). Lesions were localized to the atlanto-occipital region (2/22), C1 to C5 (7/22), C6 to T2 (4/22), T3 to L3 (3/22), and L4 to S1 (6/22). Diagnoses included vertebral fracture only (4/22), luxation only (5/22) or both vertebral fracture and luxation (13/22). In five cases, no therapy was attempted, while 12 cases were treated medically and five cases were treated surgically. Surgical interventions included manual reduction (n = 1); arthrodesis (n = 2); laminectomy (n = 1); and laminectomy with pin fixation, cerclage wire and polymethylmethacrylate bridging (n = 1). Five of the 22 cases survived to hospital discharge; two of these were treated surgically. Conclusion The cervical region was most commonly affected. Prognosis for these injuries in farm animals is guarded.

Two brothers with p47-phox-deficient chronic granulomatous disease associated with end-stage renal failure

1995 ◽  
Vol 10 (12) ◽  
pp. 2334-2336 ◽  
Author(s):  
H. Yamazaki ◽  
S. Nishi ◽  
T. Chou ◽  
Y. Nakagawa ◽  
H. Shimada ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Granulomatous Disease ◽  
Granulomatous Disease ◽  
End Stage Renal Failure ◽  
End Stage

scholarly journals Predicting the Risk of Malignancy of Lung Nodules Diagnosed as Indeterminate on Radial Endobronchial Ultrasound-Guided Biopsy

2020 ◽  
Vol 9 (11) ◽  
pp. 3652
Author(s):  
Sungmin Zo ◽  
Sook-young Woo ◽  
Seonwoo Kim ◽  
Jung Eun Lee ◽  
Byeong-Ho Jeong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Medical Center ◽  
Area Under The Curve ◽  
Final Diagnosis ◽  
Clinical Findings ◽  
Chest Ct ◽  
Endobronchial Ultrasound ◽  
Lung Nodules ◽  
Guided Biopsy ◽  
Risk Of Malignancy

The next diagnostic step in cases of indeterminate radial probe endobronchial ultrasound (radial EBUS)-guided biopsy results remains uncertain. This study aimed to identify risk factors for malignancy based on clinical findings, chest computed tomography (CT), and radial EBUS images, and to estimate the risk of malignancy in lung nodules that showed indeterminate radial EBUS-guided biopsy results by constructing a nomogram. This retrospective study included 157 patients with indeterminate results on an initial radial EBUS biopsy performed at the Samsung Medical Center from January 2017 to December 2018, but with a definitive final diagnosis. Medical records, chest CT, radial EBUS images, and the final diagnoses were reviewed. Patients were randomly divided into training and validation sets. Factors related to malignancy were identified through logistic regression analysis, and a nomogram was constructed using the training set and subsequently applied to the validation set. Six factors in univariable and multivariable analyses, including upper lobe location, spiculation, satellite nodules, echogenicity, presence of dots or linear arcs, and patency of vessels and bronchi predicted malignancy. A nomogram was constructed based on these predictors. The area under the curve (AUC) value of the nomogram was 0.858 using the chest CT factors, which improved to 0.952 when radial EBUS factors were added. The calibration curve showed good agreement between the actual and nomogram-predicted malignancy outcomes. The utility of radial EBUS images for revealing risk factors of malignancy was confirmed. Furthermore, our nomogram was able to predict the probability of malignancy in lung nodules with indeterminate radial EBUS-guided biopsy results.

scholarly journals 164 Dementia, a Familial Affair

2019 ◽  
Vol 48 (Supplement_3) ◽  
pp. iii17-iii65
Author(s):  
Aqueel Qureshi ◽  
Ahmed Gabr ◽  
Daniel Zulkifli ◽  
Elijah Chaila ◽  
Margaret O'Connor
Keyword(s):  
Family History ◽  
Rare Case ◽  
Clinical Signs ◽  
Final Diagnosis ◽  
Clinical Findings ◽  
Post Mortem ◽  
Mri Findings ◽  
Progressive Dementia ◽  
Familial Predisposition ◽  
Rasmussen’S Encephalitis

Abstract Background In Ireland, there are approximately 55,000 cases of dementia. One of the rare causes of dementia is Creutzfeldt-Jakob disease (CJD), affecting one person per million each year worldwide. It is a rapidly progressive degenerative fatal disorder with an estimated mortality of 70% within one year. In this case report we present a rare case of possible familial-CJD which presented initially as a stroke mimic. Methods A 64-year old female referred via GP with abnormal left arm athetoid movements and in-coordination. MRI brain demonstrated a small sub-acute hyper-intense lesion in the right basal ganglia on diffusion weighted imaging. Her symptoms were atypical for acute stroke, however an alternative cause was not evident. She was monitored closely with early supported discharge. However the left sided athetoid movements worsened and were associated with intermittent myoclonic jerks and dystonic posturing. She was reassessed with a wider differential including focal impaired seizures, Rasmussen’s encephalitis, and CJD. EEG showed periodic lateralizing epileptic discharges, however patient failed to show any response to anti-epileptic treatment and her clinical course was one of rapid deterioration. Clinical findings and subsequent MRI findings showed new areas of hyperintensity supporting CJD. Results Ultimately our patient deteriorated rapidly resulting in an akinetic and abulic state, resulting in death. A final diagnosis of sporadic-CJD was made based on rapid progressive deterioration and findings on MRI as well as confirmation on post-mortem brain pathology. A deeper review of family history revealed a sister who had passed away years prior with rapid progressive neurological illness. Her work-up showed clinical signs and EEG findings supporting CJD, however there was no post mortem to confirm her diagnosis. Conclusion This case highlights the importance of genetics shaping phenotypes and that consideration should always be given to a full relevant family history. It also shows a rare case of rapidly progressive dementia confirmed due to CJD with a likely underlying familial predisposition.

Ureteric Obstruction Secondary to Pelvic Actinomycosis

1988 ◽  
Vol 62 (1) ◽  
pp. 85-87 ◽  
Author(s):  
A. E. JACKSON ◽  
J. R. W. PARRY ◽  
P. J. R. SHAH
Keyword(s):  
Ureteric Obstruction ◽  
Pelvic Actinomycosis
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