scholarly journals Sex-Specific Gait Patterns of Older Adults with Knee Osteoarthritis: Results from the Baltimore Longitudinal Study of Aging

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Seung-uk Ko ◽  
Eleanor M. Simonsick ◽  
Liz M. Husson ◽  
Luigi Ferrucci

Men and women exhibit different gait patterns during customary walking and may respond differently to joint diseases. The present paper aims to identify gait patterns associated with knee-OA separately in men and women. Participants included 144 men and 124 women aged 60 years and older enrolled in the Baltimore Longitudinal Study of Aging (BLSA) who underwent gait testing at a self-selected speed. Both men and women with knee-OA had lower ankle propulsion mechanical work expenditure (MWE;P<.001for both) and higher hip generative MWE (P<.001) compared to non-OA controls. Women with knee-OA had a higher BMI (P=.008), slower gait speed (P=.049), and higher knee frontal-plane absorbing MWE (P=.007) than women without knee-OA. These differences were not observed in men. Understanding sex-specific differences in gait adaptation to knee-OA may inform the development of appropriate strategies for early detection and intervention for knee-OA in men and women.

2018 ◽  
Vol 63 ◽  
pp. 63-67 ◽  
Author(s):  
Seung-uk Ko ◽  
Gerald J. Jerome ◽  
Eleanor M. Simonsick ◽  
Stephanie Studenski ◽  
Jeffrey M. Hausdorff ◽  
...  

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 208-208
Author(s):  
Luigi Ferrucci ◽  
Eleanor Simonsick ◽  
Ajoy Karikkineth

Abstract The association between vascular health measured by arterial stiffness and fatigability, a marker of future mobility decline, is unknown. We examined 1210 men (47.7%) and women from the Baltimore Longitudinal Study of Aging, mean age 66.6 ± 13.9 years. Perceived fatigability was assessed after a 5-minute, treadmill walk using Borg rating (range 6-20). Arterial stiffness was determined by carotid femoral pulse wave velocity (PWV). In linear regression analyses fatigability and PWV were associated in men (Beta/P-value) (0.160/0.001) and women (0.136/0.008). Adjustment for mean arterial and pulse pressure attenuated the association in women (0.104/0.050) but not men (0.160/0.001). The association was significant among those with slower usual and rapid gait speeds, longer 400m walk time and slower repeated chair stands pace (all p&lt;0.05). Arterial stiffness is associated with a greater proneness to fatigue especially in older adults exhibiting poorer mobility. The underlying mechanisms appear to differ between men and women.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 578-579
Author(s):  
Darlynn Rojo-Wissar ◽  
Amal Wanigatunga ◽  
Eleanor Simonsick ◽  
Antonio Terracciano ◽  
Jennifer Schrack ◽  
...  

Abstract Personality and disturbed sleep are tied to medical morbidity in older adults. We examined associations of personality dimensions and facets from the five-factor model with reports of insomnia symptoms in 1,069 well-functioning older adults 60-97 (SD=8.64) years (51% women) from the Baltimore Longitudinal Study of Aging. Personality was assessed by the Revised NEO Personality Inventory, and insomnia symptoms measured by the Women’s Health Initiative Insomnia Rating Scale. Adjusting for demographics and depressive symptoms, higher neuroticism (B=0.05, SE=-0.01, p&lt;.001) and lower conscientiousness (B=-0.03, SE=-0.01, p&lt;.05) were associated with greater insomnia severity. Although openness, extraversion and agreeableness were not associated with insomnia, a facet of each was. Higher scores on the “positive emotions” facet of extraversion (B =-0.03, SE=-0.01, p&lt;.05) “ideas” facet of openness (B=-0.03, SE=-0.01, p&lt;.05) and altruism facet of agreeableness (B=-0.03, SE=-0.01, p&lt;.05) were associated with lower insomnia severity. Sleep disturbances may partially mediate personality’s influence on health. Part of a symposium sponsored by the Sleep, Circadian Rhythms and Aging Interest Group.


2014 ◽  
Vol 70 (11) ◽  
pp. 1297-1303 ◽  
Author(s):  
Elisa Fabbri ◽  
Yang An ◽  
Jennifer A. Schrack ◽  
Marta Gonzalez-Freire ◽  
Marco Zoli ◽  
...  

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