scholarly journals Validation of the Danish Version of Functional Assessment of Multiple Sclerosis: A Quality of Life Instrument

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Jan Sørensen ◽  
Jette Bay ◽  
Torben Damsgaard ◽  
Elsebeth Heeley ◽  
Ida Rostgaard ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Functional Status ◽  
Functional Assessment ◽  
Rehabilitation Program ◽  
Validity And Reliability ◽  
Rehabilitation Centers ◽  
Quality Scale ◽  
Danish Version ◽  
The Us

The functional assessment of multiple sclerosis (FAMS) is a disease-specific instrument that describes functional status of individuals with multiple sclerosis. The instrument was originally developed in the US and has been adapted to different languages including Danish. This study is a validation of the Danish version of FAMS in a sample of individuals referred to a four-week rehabilitation program at either of the two Multiple Sclerosis Rehabilitation centers in Denmark. FAMS data were obtained through self-completed questionnaires from 190 individuals who attended the rehabilitation centers after referral by their general practitioner or specialist neurologist. The validation of the FAMS included assessment of data quality, scale assumptions, acceptability, construct validity, and reliability. Responsiveness was assessed by comparing individual FAMS scores at admission with the discharge score for groups of respondents who reported no change, improvement, or deterioration in their ability to cope with their illness. The Danish version of FAMS appears to be an acceptable, valid, and reliable measure of current health and functional status of individuals with multiple sclerosis.

AB0871 Rehabilitation Program Improves Functional Status and Quality of life in Patients with Knee Osteoarthritis

2015 ◽  
Vol 74 (Suppl 2) ◽  
pp. 1192.1-1192
Author(s):  
R.I. Marcu ◽  
R. Traistaru ◽  
S. Patru ◽  
A.C. Bighea ◽  
R.S. Popescu
Keyword(s):  
Quality Of Life ◽  
Knee Osteoarthritis ◽  
Functional Status ◽  
Rehabilitation Program

scholarly journals Multiple Sclerosis: Overview of Disease-Modifying Agents

2014 ◽  
Vol 6 ◽  
pp. PMC.S13213 ◽  
Author(s):  
Alessandro Finkelsztejn
Keyword(s):  
Multiple Sclerosis ◽  
Healthcare Professionals ◽  
Drug Class ◽  
Cognitive Disability ◽  
Oral Drugs ◽  
The Us ◽  
Disease Modifying Agents ◽  
Phase Ii And Iii ◽  
Chronic Autoimmune Disease

Multiple sclerosis (MS) is a chronic autoimmune disease that usually affects young adults, causing progressive physical and cognitive disability. Since the 1990s, its treatment has been based on parenteral medications known collectively as immunomodulators. This drug class is considered safe and usually prevents 30% of MS relapses. Drugs in this class exert almost the same efficacy and require an inconvenient administration route. New medications have recently been launched worldwide. Thus, new oral drugs are increasingly being administered to MS patients and contributing to a better quality of life, since these have better efficacy than the old immunomodulators. Today, 10 different drugs for MS are marketed worldwide, which requires deep knowledge among neurologists and other healthcare professionals. This paper summarizes all the drugs approved for MS in the US and Europe, emphasizing their mechanism of action, the results from phase II and III studies, and the product safety.

Validation of the Multiple Sclerosis International Quality of Life questionnaire

2007 ◽  
Vol 14 (2) ◽  
pp. 219-230 ◽  
Author(s):  
MC Simeoni ◽  
P. Auquier ◽  
O. Fernandez ◽  
P. Flachenecker ◽  
S. Stecchi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Internal Consistency ◽  
Discriminant Validity ◽  
Short Form ◽  
Life Questionnaire ◽  
Validity And Reliability ◽  
Sf 36 ◽  
Quality Of Life Scale

This study aims to validate the Multiple Sclerosis (MS) International Quality of Life (MusiQoL) questionnaire, a multi-dimensional, self-administered questionnaire, available in 14 languages, as a disease-specific quality of life scale that can be applied internationally. A total of 1992 patients with different types and severities of MS from 15 countries were recruited. At baseline and day 21 ± 7, each patient completed the MusiQoL, a symptom checklist and the short-form (SF)-36 QoL questionnaire. Neurologists also collected socio-demographic, MS history and outcome data. The database was randomly divided into two subgroups and analysed according to different patient characteristics. For each model, psychometric properties were tested and the number of items was reduced by various statistical methods. Construct validity, internal consistency, reproducibility and external consistency were also tested. Nine dimensions, explaining 71% of the total variance, were isolated. Internal consistency and reproducibility were satisfactory for all the dimensions. External validity testing revealed that dimension scores correlated significantly with all SF-36 scores, but showed discriminant validity by gender, socio-economic and health status. Significant correlations were found between activity in daily life scores and clinical indices. These results demonstrate the validity and reliability of the MusiQoL as an international scale to evaluate QoL in patients with MS. Multiple Sclerosis 2008; 14: 219—230. http://msj.sagepub.com

scholarly journals Evaluation of quality of life in multiple sclerosis patients

2009 ◽  
Vol 4 (1) ◽  
pp. 156
Author(s):  
Raquel Sousa Quintanilha ◽  
Luciano Ramos de Lima
Keyword(s):  
Multiple Sclerosis ◽  
Family Support ◽  
Functional Assessment ◽  
Emotional State ◽  
Correlation Coefficients ◽  
Descriptive Study ◽  
Ethics Committee ◽  
Personal Satisfaction ◽  
Multiple Sclerosis Patients

ABSTRACTObjective: to evaluaty the quality of live in Multiple Sclerosis patients. Methods: exploratory descriptive study, from quantitative approach, performed with 13 subjects with confirmed clinical diagnosis. The instrument used for data collection was the Functional Assessment of Multiple Sclerosis (FAMS) translated into Portuguese as Escala de Determinação Funcional de Qualidade de Vida em pacientes com Esclerose Múltipla (DEFU). The research project has been approved by the Ethics Committee according protocol number 096/2008. Results: there was a prevalence of women (69.2%) with a mean age of 48.7 years old (SD = 10.45). The aspect which had the highest deficit index was Thinking and Fatigue (M=22.31), followed by Personal Satisfaction (M=16.77), Social and Familiar Status (M=13.08), Mobility (M=12.46), Symptoms (M=11.46) and Emotional State (M=8.31). Emotional State was the aspect with the lowest score for the patients obtained an adequate family support. The reliability of the correlation coefficients among the DEFU sub-scales showed significant results (p

Reliability and validity of the Functional Assessment of Cancer Therapy-Breast quality-of-life instrument.

1997 ◽  
Vol 15 (3) ◽  
pp. 974-986 ◽  
Author(s):  
M J Brady ◽  
D F Cella ◽  
F Mo ◽  
A E Bonomi ◽  
D S Tulsky ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Therapy ◽  
Functional Assessment ◽  
Performance Status ◽  
Well Being ◽  
Self Report ◽  
Sensitivity To Change ◽  
Validity And Reliability

PURPOSE This is the first published report on the validation of the Functional Assessment of Cancer Therapy-Breast (FACT-B), a 44-item self-report instrument designed to measure multidimensional quality of life (QL) in patients with breast cancer. The FACT-B consists of the FACT-General (FACT-G) plus the Breast Cancer Subscale (BCS), which complements the general scale with items specific to QL in breast cancer. The FACT-B was developed with an emphasis on patients' values and brevity and is available in nine languages. METHODS AND RESULTS Two validation samples were used for this report. The first (n = 47) was tested twice over a 2-month period to assess sensitivity to change. Significant sensitivity to change in performance status rating (PSR) was demonstrated for the FACT-B total score, the Physical Well-Being (PWB) subscale, the Functional Well-Being (FWB) subscale, and the BCS. Sensitivity to change in QL as measured by the Functional Living Index-Cancer (FLIC) was documented in the FACT-B total score, PWB, FWB, and Emotional Well-Being (EWB). Additional validity and reliability data were obtained from a larger sample (n = 295). The alpha coefficient (internal consistency) for the FACT-B total score was high (alpha = .90), with subscale alpha coefficients ranging from .63 to .86. Evidence supported test-retest reliability, as well as convergent, divergent, and known groups validity. CONCLUSION The FACT-B is appropriate for use in oncology clinical trials, as well as in clinical practice. It demonstrates ease of administration, brevity, reliability, validity, and sensitivity to change.

Investigation of the validity and reliability of the Turkish version of the Functional Assessment of Cancer Therapy—Cognitive Function in cancer patients

2021 ◽  
pp. 1-7
Author(s):  
Songül Atasavun Uysal ◽  
Vesile Yildiz Kabak ◽  
Yusuf Karakas ◽  
Erdem Karabulut ◽  
Deniz Erdan Kocamaz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Function ◽  
Cancer Therapy ◽  
Cancer Patients ◽  
Functional Assessment ◽  
Cognitive Functions ◽  
Validity And Reliability ◽  
Turkish Version ◽  
Eortc Qlq

Abstract Objective The Functional Assessment of Cancer Therapy—Cognitive Function (FACT-Cog) is a questionnaire that is used to evaluate the quality of life and cognitive functions according to individual self-reports. The aim of this study was to investigate the validity and reliability of the Turkish version of the FACT-Cog. Methods Cancer patients who were treated with chemo or radiotherapy and had a score of 24/30 and more in Mini-Mental State Examination (MMSE) were included in this study. Cognitive functions assessed with the FACT-Cog and the European Organization of Research and Treatment of Cancer Quality of Life Core Questionnaire Core 30: Cognitive Function subscale (EORTC QLQ-CF). Results One hundred and forty cancer patients [female = 87 (62.1%), male = 53 (37.9%)] were included. The mean age of the participants was 47.93 ± 11.90 years. The Cronbach's α of the FACT-Cog scale was 0.82. Test–retest intraclass correlation coefficient values of the FACT-Cog questionnaire were varied from 0.855 to 0.954. There were found low correlations between the total score of the FACT-Cog and the MMSE (r = 0.26, p = 0.002), and moderate correlations between the EORTC QLQ-CF subscale and the FACT-Cog (r = −0.43; p < 0.001). Significance of results It showed the validity and reliability of the Turkish version of the FACT-Cog questionnaire for cancer patients. It may be beneficial to use this questionnaire for the effects of cancer treatment.

Validation of the Functional Assessment of Multiple Sclerosis quality of life instrument

Neurology ◽  
1996 ◽  
Vol 47 (1) ◽  
pp. 129-139 ◽  
Author(s):  
D. F. Cella ◽  
K. Dineen ◽  
B. Arnason ◽  
A. Reder ◽  
K. A. Webster ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Functional Assessment ◽  
Life Instrument
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