scholarly journals Two Cases of Small Cell Carcinoma of the Gallbladder

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Peter Nau ◽  
James Liu ◽  
Mary Dillhoff ◽  
Meghan Forster ◽  
Jeffrey Hazey ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Disease Process ◽  
Standard Of Care ◽  
Radical Resection ◽  
Medical Intervention ◽  
Small Cell ◽  
Current Standard ◽  
Female Population ◽  
Carcinoma Of The Gallbladder

Small cell carcinoma of the gallbladder is a rare disease process with approximately 40 cases reported in the literature. It is most often found in elderly female population and is associated with cholelithiasis and cigarette smoking. A multidisciplinary approach to treatment with wide surgical resection and adjuvant chemotherapy is the current standard of care. Notwithstanding prompt medical intervention, it is a disease with a poor prognosis. The pathology is characterized by early metastases and extensive local invasion. Herein, we report two cases of small cell carcinoma addressed at our institution. In both cases, a radical resection was performed with subsequent referral to oncology for additional therapy.

scholarly journals Small Cell Ovarian Cancer in Adolescents: Report of Two Cases and Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
M. Rovithi ◽  
A. G. Pallis ◽  
A. Kalykaki ◽  
E. Lagoudaki ◽  
L. Giannikaki ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Combination Chemotherapy ◽  
Poor Prognosis ◽  
Relevant Literature ◽  
Malignant Neoplasm ◽  
Standard Of Care ◽  
Small Cell ◽  
Review Of The Literature

Ovarian small cell carcinoma is a rare and highly malignant neoplasm carrying a poor prognosis. Although combination chemotherapy remains the cornerstone of treatment due to the rarity of these tumors, no regimen can be recommended as standard of care although in the majority of cases platinum-based regimens are used. Herein, we report two cases of small cell carcinoma of the ovaries along with a review of the relevant literature.

scholarly journals A case of primary small cell carcinoma of the gallbladder.

1989 ◽  
Vol 22 (7) ◽  
pp. 1887-1890
Author(s):  
Koichi MOTOSHIMA ◽  
Sigeto MAEDA ◽  
Takafumi URAKAWA ◽  
Yuji KAJIYAMA ◽  
Yoshihiko SAKAMOTO ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Carcinoma Of The Gallbladder

scholarly journals A dural metastatic small cell carcinoma of the gallbladder as the first manifestation: a case report

2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Shuichi Tonomura ◽  
Tomoko Kitaichi ◽  
Rina Onishi ◽  
Yoshiaki Kakehi ◽  
Hisao Shimizu ◽  
...  
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Carcinoma Of The Gallbladder

Small Cell Carcinoma of the Gallbladder: Clinical Course and Response to Chemotherapy

1992 ◽  
Vol 78 (3) ◽  
pp. 207-210 ◽  
Author(s):  
Ilan-Gil Ron ◽  
Nelly Wigler ◽  
Bianca Ilie ◽  
Samario Chaitchik
Keyword(s):  
Partial Response ◽  
Gall Bladder ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Clinical Course ◽  
Small Cell ◽  
Rare Tumor ◽  
Carcinoma Of The Gallbladder ◽  
Response To Chemotherapy ◽  
Oat Cell Carcinoma

Small cell carcinoma of the gall bladder is a rare tumor. The neoplasm is highly lethal, metastasizes early, and may cause death shortly after diagnosis. An oat cell carcinoma of the gallbladder metastatic to the liver and adjacent lymph nodes is described in a 60-year-old male. Partial cholecystectomy was performed followed by aggressive chemotherapy with etoposide and cisplatinum. An 80 % reduction in the size of the unexcised tumor was noted over a period of 6 months. The partial response and the relatively long survival of the patient suggest the use of the above protocol for these rare cases.

scholarly journals Small Cell Carcinoma of the Gallbladder: Case Report and Comprehensive Analysis of Published Cases

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Carolyn Carrera ◽  
Paul Kunk ◽  
Osama Rahma
Keyword(s):  
Overall Survival ◽  
Case Report ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Metastatic Disease ◽  
Median Overall Survival ◽  
Case Reports ◽  
Small Cell ◽  
Carcinoma Of The Gallbladder ◽  
Local Disease

Background. Gallbladder small cell carcinoma is a rare and highly aggressive malignancy with no established standard of care treatment. We described here a case report of small cell gallbladder cancer and we then performed a comprehensive review of 72 case reports of this disease.Methods. Published case reports of small cell carcinoma of the gallbladder between 1983 and 2014 were reviewed. Treatment modalities and survival were analyzed for metastatic and localized disease.Results. Median overall survival for all patients was 13 months. Metastatic disease was identified in 72% of cases. Treatment of metastatic disease with chemotherapy showed a significant survival benefit (p<0.001) compared to no chemotherapy, and the use of platinum doublet with etoposide showed a nonsignificant 4-month improvement in survival compared to other chemotherapy regimens (p=0.13). Adjuvant therapy did not demonstrate an improvement of median overall survival in local disease (p=0.78).Conclusion. Given the limited available data, systemic therapy with platinum and etoposide should be considered for patients with metastatic small cell carcinoma of the gallbladder. Adjuvant chemoradiation or chemotherapy for treatment of local disease warrants further investigation.

Small cell carcinoma of the gallbladder

1999 ◽  
Vol 70 (1) ◽  
pp. 54-59 ◽  
Author(s):  
Thomas L. Moskal ◽  
Paul J. Zhang ◽  
Hector R. Nava
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Carcinoma Of The Gallbladder

scholarly journals A CASE OF SMALL CELL CARCINOMA OF THE GALLBLADDER

2010 ◽  
Vol 71 (8) ◽  
pp. 2129-2133 ◽  
Author(s):  
Takahiro SASAKI ◽  
Shinjiro KOBAYASHI ◽  
Satoshi KOIZUMI ◽  
Takeshi ASAKURA ◽  
Hiroshi NAKANO ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Carcinoma Of The Gallbladder

Small Cell Carcinoma of the Gallbladder

1998 ◽  
Vol 98 (3) ◽  
pp. 110-112
Author(s):  
J. M. Debois ◽  
P. De Vriendt ◽  
K. Charels
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Carcinoma Of The Gallbladder
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