scholarly journals Leiomyosarcoma Arising in the Pancreatic Duct: A Case Report and Review of the Current Literature

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Nicole D. Riddle ◽  
Brian C. Quigley ◽  
Irwin Browarsky ◽  
Marilyn M. Bui
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Pancreatic Duct ◽  
World Literature ◽  
Smooth Muscle Actin ◽  
Care Center ◽  
Tertiary Care ◽  
Immunohistochemical Markers ◽  
Large Tertiary Care ◽  
Rare Malignancy

Context. Leiomyosarcomas are rare malignant smooth muscle tumors that may arise in any organ or tissue that contains smooth muscle, commonly within the gastrointestinal tract. They are most often found in the stomach, large and small intestines, and retroperitoneum. Primary pancreatic leiomyosarcoma is extremely rare, and to the best of our knowledge only 30 cases have been reported in the world literature since 1951. Our case represents the first to have a clear origin from the main pancreatic duct.Case Report. This case was diagnosed in a large, tertiary care center in Tampa, Florida. Pertinent information was obtained from chart review and interdepartmental collaboration. A mass in the tail of the pancreas was identified with large pleomorphic and spindle-shaped cells. Immunohistochemistry for vimentin, smooth muscle actin, and desmin was positive. All remaining immunohistochemical markers performed were negative. The tumor clearly originated from the pancreatic duct wall, filled and expanded the duct lumen, and was covered with a layer of benign biliary epithelium.Conclusion. Leiomyosarcoma of the pancreas is an extremely rare malignancy with few reported cases in the literature. The prognosis is poor, and treatment consists of alleviating symptoms and pain management. To our knowledge, this represents the first reported case demonstrating clear origin of a leiomyosarcoma from the pancreatic duct.

MESENCHYMAL TUMOR LEIOMYOSARCOMA OF PROSTATE, A RARE CASE REPORT

2021 ◽  
pp. 21-22
Author(s):  
Ekta Rani ◽  
Sarita Nibhoria ◽  
Bikramjit Singh ◽  
Aradhana Singh Hada ◽  
Parminderjeet Singh Sandhu
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Tumor Cells ◽  
Poor Prognosis ◽  
Rare Case ◽  
Smooth Muscle Actin ◽  
Mesenchymal Tumor ◽  
Muscle Actin ◽  
Rare Case Report ◽  
Rare Malignancy

Primary prostate sarcoma is a rare malignancy of the prostate with poor prognosis. It accounts for <1% of the tumors of the prostate. Leiomyosarcoma is the most common sarcoma involving the prostate in adults affecting men between the ages of 40 and 78 years. Tumor cells commonly express vimentin, smooth muscle actin and desmin, and up to 25% express cytokeratins.

ID: 3523845 THE USE OF EUS AND ERCP IN THE DIAGNOSIS OF EXTRAHEPATIC BILIARY CHOLANGIOCARCINOMA. EXPERIENCE FROM A LARGE TERTIARY CARE CENTER

2021 ◽  
Vol 93 (6) ◽  
pp. AB139-AB140
Author(s):  
Martin Coronel ◽  
Firas Bahdi ◽  
Disha Kumar ◽  
Shria Kumar ◽  
Phillip Lum ◽  
...  
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Large Tertiary Care

scholarly journals Large intraperitoneal lipoleiomyoma in a pre-menopausal woman: a case report

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Sara L. Schaefer ◽  
Amy L. Strong ◽  
Sheena Bahroloomi ◽  
Jichang Han ◽  
Michella K. Whisman ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Case Report ◽  
Smooth Muscle Actin ◽  
Abdominal Mass ◽  
Histopathological Analysis ◽  
Menopausal Woman ◽  
En Bloc ◽  
Cross Sectional

Abstract Background Lipoleiomyoma is a rare, benign variant of the commonplace uterine leiomyoma. Unlike leiomyoma, these tumors are composed of smooth muscle cells admixed with mature adipose tissue. While rare, they are most frequently identified in the uterus, but even more infrequently have been described in extrauterine locations. Case presentation We describe a case report of a 45-year-old woman with a history of in vitro fertilization pregnancy presenting 6 years later with abdominal distention and weight loss found to have a 30-cm intra-abdominal lipoleiomyoma. While cross-sectional imaging can narrow the differential diagnosis, histopathological analysis with stains positive for smooth muscle actin, desmin, and estrogen receptor, but negative for HMB-45 confirms the diagnosis of lipoleiomyoma. The large encapsulated tumor was resected en bloc. The patients post-operative course was uneventful and her symptoms resolved. Conclusions Lipoleiomyoma should be considered on the differential diagnosis in a woman with a large intra-abdominal mass. While considered benign, resection should be considered if the mass is symptomatic, and the diagnosis is unclear or there is a concern for malignancy.

scholarly journals Neurological manifestations of COVID-19 in confirmed and probable cases: A descriptive study from a large tertiary care center

2021 ◽  
Vol 86 ◽  
pp. 97-102
Author(s):  
Hatice Yuksel ◽  
Gorkem Tutal Gursoy ◽  
Ebru Bilge Dirik ◽  
Safiye Gul Kenar ◽  
Hesna Bektas ◽  
...  
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Tertiary Care Center ◽  
Neurological Manifestations ◽  
Large Tertiary Care

scholarly journals Metastatic Parotid Myoepithelial Carcinoma in a 7-Year-Old Boy

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Issam Saliba ◽  
Nazir El Khatib ◽  
Antoine Nehme ◽  
Selim Nasser ◽  
Nabil Moukarzel
Keyword(s):  
Parotid Gland ◽  
Facial Nerve ◽  
Smooth Muscle Actin ◽  
Postoperative Radiotherapy ◽  
Lumbar Vertebra ◽  
Myoepithelial Carcinoma ◽  
Cervical Lymph Nodes ◽  
Immunohistochemical Markers ◽  
First Case ◽  
Rare Malignancy

Myoepithelial carcinoma is a rare malignancy of the parotid gland that is usually seen in adults. We report the first case in children of myoepithelial carcinoma of the parotid gland with massive invasion of the facial nerve and metastasis to cervical lymph nodes. Due to its rarity, the treatment and the clinical course of this tumor are not well defined yet. We performed a total parotidectomy, a modified neck dissection, and a postoperative radiotherapy in 7-year-old boy. Sparing of the facial nerve was impossible; it was sacrificed and grafted with a sural nerve. Histopathology confirmed the diagnosis of a parotid gland carcinoma and immunohistochemical markers showed that the tumor cells express cytokeratin, epithelial membrane antigen, cytokeratin 7, smooth muscle actin, P63, CEA, and S100. This pattern of immunostaining is consistent with the diagnosis of myoepithelial carcinoma. On the postoperative tenth month he presented with a pulmonary and lumbar vertebra metastasis.

Analyzing Atypical Urine Cytology Specimens with the Paris Criteria in a Large Tertiary Care Center

2016 ◽  
Vol 5 (5) ◽  
pp. S22-S23
Author(s):  
Linette Mejias ◽  
Elly Landolfi ◽  
Tatyana Kalinicheva ◽  
Dongping Shi ◽  
Sudeshna Bandyopadhyay ◽  
...  
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Urine Cytology ◽  
Tertiary Care Center ◽  
Large Tertiary Care

scholarly journals Prevalence of pathological myopia among patients in a large tertiary care center in Egypt

2018 ◽  
Vol 4 (5) ◽  
Author(s):  
Ayman Gehad Elnahry ◽  
Mohamed Mahmoud Khafagy ◽  
Soheir Mohamed Esmat ◽  
Hassan Aly Mortada
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Pathological Myopia ◽  
Large Tertiary Care

scholarly journals Case Report: A giant myopericytoma involving the occipital region of the scalp - a rare entity

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 2905 ◽  
Author(s):  
Sunil Munakomi ◽  
Pramod Chaudhary
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Histological Examination ◽  
Rare Case ◽  
Smooth Muscle Actin ◽  
Positive Staining ◽  
Occipital Region ◽  
Rare Entity ◽  
Muscle Actin ◽  
Complete Excision

Herein we report a rare case of a giant myopericytoma presenting in a 16-year-old girl as a slowly progressive swelling involving the scalp in the occipital region. It was managed by complete excision. Histological examination of the lesion revealed  spindle-shaped cells forming characteristic rosettes around the blood vessels, and positive staining with smooth muscle actin.

scholarly journals Clinical and Microbiological Characteristics of Colistin-Resistant Enterobacteriaceae at a Large Tertiary Care Center in Michigan

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S149-S149
Author(s):  
John P Mills ◽  
Oryan Henig ◽  
Twisha Patel ◽  
Laraine L Washer ◽  
Michael A Bachman ◽  
...  
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Microbiological Characteristics ◽  
Large Tertiary Care
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