scholarly journals Clinical Relevance of Transjugular Liver Biopsy in Comparison with Percutaneous and Laparoscopic Liver Biopsy

2009 ◽  
Vol 2009 ◽  
pp. 1-7 ◽  
Author(s):  
Max G. Beckmann ◽  
Matthias J. Bahr ◽  
Johannes Hadem ◽  
Martin Bredt ◽  
Heiner Wedemeyer ◽  
...  
Keyword(s):  
Liver Biopsy ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Clinical Relevance ◽  
Clinical Decision ◽  
Hepatocellular Necrosis ◽  
Transjugular Liver Biopsy ◽  
Risk Patients ◽  
Liver Biopsies ◽  
The Impact

Background. Transjugular liver biopsy (TJLB) is frequently used to obtain liver specimens in high-risk patients. However, TJLB sample size possibly limits their clinical relevance.Methods. 102 patients that underwent TJLB were included. Clinical parameters and outcome of TJLB were analyzed. Control samples consisted of 112 minilaparoscopic liver biopsies (mLLBs) and 100 percutaneous liver biopsies (PLBs).Results. Fewer portal tracts were detected in TJLB (4.3±0.3) in comparison with PLB (11.7±0.5) and mLLB (11.0±0.6). No difference regarding the specification of indeterminate liver disease and staging/grading of chronic hepatitis was observed. In acute liver failure (n=32), a proportion of hepatocellular necrosis beyond 25% was associated with a higher rate of death or liver transplantation.Conclusions. Despite smaller biopsy samples the impact on the clinical decision process was found to be comparable to PLB and mLLB. TJLB represents a helpful tool to determine hepatocellular necrosis rates in patients with acute liver failure.

Contribution of Transjugular Liver Biopsy in Patients with the Clinical Presentation of Acute Liver Failure

2006 ◽  
Vol 29 (6) ◽  
pp. 1008-1010 ◽  
Author(s):  
Roberto Miraglia ◽  
Angelo Luca ◽  
Salvatore Gruttadauria ◽  
Marta Ida Minervini ◽  
Giovanni Vizzini ◽  
...  
Keyword(s):  
Liver Biopsy ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Clinical Presentation ◽  
Transjugular Liver Biopsy

Liver Biopsy Can Be Safely Performed in Pediatric Acute Liver Failure to Aid in Diagnosis and Management

2018 ◽  
Vol 67 (4) ◽  
pp. 441-445 ◽  
Author(s):  
Catherine A. Chapin ◽  
Saeed Mohammad ◽  
Lee M. Bass ◽  
Sarah A. Taylor ◽  
Susan Kelly ◽  
...  
Keyword(s):  
Liver Biopsy ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Diagnosis And Management ◽  
Pediatric Acute Liver Failure

Transjugular liver biopsy in high-risk patients with hepatic disease.

Radiology ◽  
1984 ◽  
Vol 153 (1) ◽  
pp. 91-93 ◽  
Author(s):  
P M Velt ◽  
O G Choy ◽  
P M Shimkin ◽  
R J Link
Keyword(s):  
High Risk ◽  
Liver Biopsy ◽  
Hepatic Disease ◽  
High Risk Patients ◽  
Transjugular Liver Biopsy ◽  
Risk Patients

461: The Impact of Body Mass Index on Acute Liver Failure Patient Outcomes

2020 ◽  
Vol 49 (1) ◽  
pp. 221-221
Author(s):  
Julianne Kleitsch ◽  
Neha Dangayach ◽  
Thomas Schiano ◽  
Alexandra Reynolds
Keyword(s):  
Body Mass Index ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Body Mass ◽  
Patient Outcomes ◽  
The Impact

scholarly journals Transjugular Liver Biopsy Following Orthotopic Whole Liver Transplantation: Challenges and Solutions. A Pictorial Essay

2017 ◽  
Vol 01 (02) ◽  
pp. 107-112 ◽  
Author(s):  
Claire Kaufman ◽  
Jordana Gaumond ◽  
John Kaufman
Keyword(s):  
Liver Biopsy ◽  
Rapid Diagnosis ◽  
Liver Transplants ◽  
Venous Anatomy ◽  
Venous Anastomosis ◽  
Transjugular Liver Biopsy ◽  
Different Types ◽  
Pictorial Essay ◽  
Liver Biopsies ◽  
Diagnosis Of Rejection

AbstractRejection is a common problem after orthotopic liver transplant. The tissue is required for the rapid diagnosis of rejection. Many of these patients have contraindications to percutaneous liver biopsies. Transjugular liver biopsies in patients with liver transplants can be very challenging due to the modified venous anatomy. This article will review the different types of surgical venous anastomosis in patients with whole liver transplants as well as the challenges and techniques to overcome these and successfully perform a transjugular liver biopsy.

scholarly journals Diffuse Liver Metastasis of Small-Cell Lung Cancer Presenting as Acute Liver Failure and Diagnosed by Transjugular Liver Biopsy: A Rare Case in Whom Nodular Lesions Were Detected by Enhanced CT Examination

2015 ◽  
Vol 9 (1) ◽  
pp. 81-87 ◽  
Author(s):  
S. Mishima ◽  
Y. Nozaki ◽  
S. Mikami ◽  
E. Kihira ◽  
M. Iikura ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Liver Metastasis ◽  
Liver Biopsy ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Liver Metastases ◽  
Small Cell ◽  
Small Cell Lung ◽  
Enhanced Ct ◽  
Nodular Lesions

Small-cell lung cancer (SCLC) is a subgroup of lung cancer with a high frequency of liver metastasis, which is a predictor of poor prognosis. Diffuse liver metastases of SCLC with no visible nodular lesions in the liver when examined using computed tomography (CT) are relatively rare; however, a few cases with rapid progression to acute liver failure that were diagnosed after death have been reported. In this paper, we report a 63-year-old man with diffuse liver metastases of SCLC that were histologically diagnosed using a transjugular liver biopsy while the patient was alive, even though no lesions were visible during a contrast-enhanced CT examination.

Expanding the Boundaries of Combined Renal Replacement Therapy for Non-Renal Indications

2018 ◽  
Vol 47 (1-3) ◽  
pp. 69-72 ◽  
Author(s):  
Mayanka Kamboj ◽  
Amir Kazory
Keyword(s):  
Hepatic Encephalopathy ◽  
Renal Replacement Therapy ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Replacement Therapy ◽  
Ammonia Level ◽  
Clinical Aspects ◽  
Optimal Timing ◽  
The Impact

Over the last decades, there have been major advancements in the field of renal replacement therapy (RRT) with utilization of newer technologies and advent of various modalities. Once exclusively used for treatment of renal failure and its metabolic consequences, the science of RRT has expanded to include non-renal indications such as treatment of fluid overload in patients with refractory heart failure. Hepatic encephalopathy due to sudden rise in serum ammonia level in the setting of acute liver failure represents an underexplored area in which RRT can potentially be helpful. While the key role of hyperammonemia in the pathogenesis of hepatic encephalopathy in patients with liver failure is well established, emerging data points to distinct pathophysiologic mechanisms underlying chronic alterations in neural metabolic functions and acute changes in cerebral perfusion. In the acute setting, ammonia can cross the blood–brain barrier at high levels leading to sudden formation of strong osmolytes, significant transcellular shift of water, and cerebral edema. Herein, we provide a brief overview of the role of RRT in management of acute hyperammonemia in the setting of acute liver failure and discuss the practical aspects of the available therapeutic modalities. Larger studies are needed to shed light on a number of clinical aspects such as the impact on the outcomes, criteria for selection of the patients that would benefit most from this therapeutic approach, optimal timing of initiation of RRT, and the most appropriate modality.

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