scholarly journals Comparative Clinical Study of Two Tooth Bleaching Protocols with 6% Hydrogen Peroxide

2009 ◽  
Vol 2009 ◽  
pp. 1-5 ◽  
Author(s):  
Jesús Oteo Calatayud ◽  
Paloma Mateos de la Varga ◽  
Carlos Oteo Calatayud ◽  
María José Calvo Box
Keyword(s):  
Hydrogen Peroxide ◽  
Clinical Efficacy ◽  
Repeated Measures ◽  
Tooth Bleaching ◽  
Over The Counter ◽  
Group I ◽  
Repeated Measures Analysis ◽  
Comparative Clinical Study ◽  
Shade Guide ◽  
Single Blind

Objective.The objective was to compare the clinical efficacy of two different tooth bleaching protocols after 1 and 2 weeks of treatment with an over-the-counter paint-on gel containing 6% hydrogen peroxide.Material and methods.Sixteen volunteer patients (minimum shade A2 or darker on maxillary teeth) were selected to participate in this randomized, single-blind (examiner-blinded), single-center, 2-group clinical trial using a divided mouth model. The product was applied in our clinic to one hemi-arch (Group I) in each patient at two sessions one week apart, making five applications at each session (separated by 10 min intervals). The patients themselves applied the product once a day for 10 days in the other hemiarch (Group II). Efficacy was measured according to the Vita Classical shade guide at baseline and at one and two weeks. Differences between groups (office-treated vs. home-treated hemiarches) were tested by repeated-measures analysis of variance.Results.Significant () differences in shade values were detected between pre- and post-bleaching in both groups. The two groups did not significantly differ in tooth shade at the end of the treatment.Conclusions.Treatment with 6% hydrogen peroxide gel using the paint-on system shows significant clinical efficacy whether applied by clinicians or by the patients themselves.

scholarly journals Combination of at-home and in-office bleaching techniques: case series

2021 ◽  
Vol 69 ◽  
Author(s):  
Marcela Alvarez FERRETTI ◽  
Matheus KURY ◽  
Beatriz Curvello de MENDONÇA ◽  
Marcelo GIANNINI ◽  
Vanessa CAVALLI ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Case Series ◽  
Tooth Bleaching ◽  
Central Incisor ◽  
Carbamide Peroxide ◽  
Tooth Sensitivity ◽  
Tooth Color ◽  
Shade Guide ◽  
At Home

ABSTRACT Tooth bleaching is one of the most conservative aesthetic techniques. At-home and in-office bleaching may be performed, as well as the combination of both techniques. As this combination may be done in different manners, distinct orders of combinations were proposed in this report. A 24 years-old man, whose upper central incisor and canine shades were A2 and A3 respectively, was initially treated by chair-side with 40-min application of 40% hydrogen peroxide (HP) for two sessions. Afterwards, an two-week overnight at-home bleaching was performed with 10% carbamide peroxide (CP). The shade of upper central incisors changed to 1M1 and canine was B1. Conversely, a 30 years-old woman was firstly conducted with at-home bleaching (overnight 4-weeks 10% CP) and, subsequently, with a single appointment of in-office bleaching for 45 minutes (35% HP). The shade of her upper central incisor changed from A1 to 0.5M1 and the upper canine from A3 to B1. The VITA classical (A1-D4) shade guide and VITA Bleached guide 3D-MASTER were used to determine the tooth color during the treatments. In both bleaching treatments, patients reported no significant tooth sensitivity and the final outcomes met their expectation.

Evaluation of Genotoxicity and Efficacy of At-home Bleaching in Smokers: A Single-blind Controlled Clinical Trial

2015 ◽  
Vol 40 (2) ◽  
pp. E47-E55 ◽  
Author(s):  
JL de Geus ◽  
M Rezende ◽  
LS Margraf ◽  
MC Bortoluzzi ◽  
E Fernández ◽  
...  
Keyword(s):  
Repeated Measures ◽  
Smoking Habit ◽  
Gingival Tissue ◽  
Controlled Study ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Shade Guide ◽  
Experimental Group ◽  
Single Blind ◽  
At Home

SUMMARY Objective This single-blind controlled study evaluated the genotoxicity and efficacy of at-home bleaching in smokers and nonsmokers. Methods We selected 60 patients with central incisors A2 or darker: 30 smokers (experimental group) and 30 nonsmokers (control group). The bleaching was carried out with 10% carbamide peroxide for three hours a day for three weeks. The color was evaluated using a shade guide, Vita Bleachedguide 3D-Master, at baseline, during bleaching (first, second, and third weeks), and one week and one month after bleaching. Smears were obtained with a moistened wooden spatula from marginal gingiva. All the cytologic smears were stained with Giemsa solution. From each slide, 1000 cells were examined under 40× magnification and where micronuclei (MN) were located, they were examined under 100× magnification. The change in shade guide units at the different assessment periods and the frequency of MN were subjected to a two-way repeated measures analysis of variance and Tukey test (α=0.05). Results In both groups we detected a whitening of approximately 4 to 5 shade guide units, without color rebound after one month (p>0.05). The frequency of MN was significantly higher in the experimental group than in the control group, regardless of the bleaching treatment (p>0.001). Conclusion The efficacy of bleaching does not appear to be affected by the smoking habit. Additionally, at-home bleaching did not induce DNA damage to the gingival tissue during the bleaching period.

scholarly journals In-Office Tooth Bleaching for Adolescents Using Hydrogen Peroxide-Based Gels: Clinical Trial

2017 ◽  
Vol 28 (6) ◽  
pp. 720-725 ◽  
Author(s):  
Marcela Leticia Leal Gonçalves ◽  
Antonio Carlos da Silva Tavares ◽  
Ana Carolina Costa da Mota ◽  
Luiz Alberto Plácido Penna ◽  
Alessandro Melo Deana ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Hydrogen Peroxide ◽  
Statistical Significance ◽  
Young Patients ◽  
Tooth Bleaching ◽  
Controlled Clinical Trial ◽  
Tooth Sensitivity ◽  
Tooth Color ◽  
Bleaching Procedure ◽  
Shade Guide

Abstract The aim of the present study was to evaluate colorimetric changes and tooth sensitivity in adolescents and young patients submitted to tooth bleaching with 20% and 35% hydrogen peroxide. A randomized, controlled, clinical trial was conducted with 53 patients aged 11 to 24 years who were allocated to groups based on the use of the following commercial products: Whiteness HP - FGM® (35% hydrogen peroxide); Whiteness HP Blue Calcium - FGM® (35% hydrogen peroxide); and Whiteness HP Blue Calcium - FGM® (20% hydrogen peroxide). After the bleaching procedure, the visual analog scale was used to measure tooth sensitivity and the Vita Classical Shade guide was used to determine changes in tooth color. Statistical analysis involved the Friedman, Kruskal-Wallis and Student-Newman-Keuls tests, with p≤0.05 considered indicative of statistical significance. The addition of calcium contributed to a reduction in tooth sensitivity, especially when the lower concentration of hydrogen peroxide (20%) was used. Tooth sensitivity occurred in a transitory way and did not influence the tooth bleaching process. Significant differences in color were found after each of the two bleaching sessions. In-office tooth bleaching was considered an effective method for adolescents and young adults. Further studies in this population are necessary in order to fully evaluate the effects of bleaching in young teeth.

scholarly journals Effects of At-home Bleaching in Smokers: 30-month Follow-up

2017 ◽  
Vol 42 (6) ◽  
pp. 572-580 ◽  
Author(s):  
JL de Geus ◽  
E Fernández ◽  
S Kossatz ◽  
AD Loguercio ◽  
A Reis
Keyword(s):  
Repeated Measures ◽  
Dental Bleaching ◽  
Dental Prophylaxis ◽  
Daily Food ◽  
Repeated Measures Analysis ◽  
Before And After ◽  
Assessment Time ◽  
Shade Guide ◽  
At Home

SUMMARY Objective: This clinical study evaluated the color longevity after 30 months of at-home bleaching with 10% carbamide peroxide (CP) in smokers and nonsmokers. Methods: Sixty patients, 30 smokers and 30 nonsmokers, were subjected to bleaching with 10% CP (Whiteness Perfect–FGM) for three hours daily for three weeks. The color was measured at baseline and at one month and 30 months after the completion of dental bleaching using the shade guide Vita classical organized by value (ΔSGU) and the shade guide Vita Bleachedguide 3D-MASTER. At the 30-month recall, the color was assessed before and after dental prophylaxis. Data from color evaluation were analyzed by two-way repeated-measures analysis of variance and Tukey test for the contrast of means (α=0.05). Results: Twenty-one smokers and 22 nonsmokers attended the 30 month recall. For both shade guides, only the main factor of assessment time was statistically significant (p<0.001). Effective whitening was observed in both groups at the baseline, which was stable at one month. However, color rebound was observed after 30 months for both groups of participants when color was measured before and after dental prophylaxis. Conclusion: Thirty months after at-home bleaching with 10% CP gel, dental darkening was detected in both groups, which cannot be solely attributed to stains caused by extrinsic staining from daily food, drinks, and smoke (in smokers).

Correlation Among Methods to Measure Tooth Color in Clinical Trials Evaluating Tooth Bleaching

2019 ◽  
Vol 1 (1) ◽  
pp. 46-52 ◽  
Author(s):  
André Luis Faria-e-Silva
Keyword(s):  
Repeated Measures ◽  
Color Change ◽  
Correlation Coefficients ◽  
Wilcoxon Test ◽  
Tooth Bleaching ◽  
Color Measurement ◽  
Tooth Color ◽  
Color Changes ◽  
Assessment Time ◽  
Shade Guide

<P>Objective: This study aimed to assess possible differences in results provided by two shade guides and a spectrophotometer used to measure the color changes during tooth bleaching. </P><P> Methods: Fifty-six patients underwent two sessions of in-office tooth bleaching with a 35% hydrogen peroxide with a week of an interval between them. The color evaluation was performed using shade match with two guide scales (Vita Classical, and Vita Bleach Guide) and a spectrophotometer providing CieLab data. The color was assessed at baseline and 7 days after each session, and 30 days after the last session. Data from scales were arranged in scores according to lightness (lowest to highest) and the color changes were calculated based on baseline data. For CieLab data, &#916;L, &#916;a, &#916;b, and &#916;E were calculated for each assessment time. Differences between the color changes observed in each session were assessed by Wilcoxon test (&#945; = 0.05). Friedman`s test and One-way repeated measures ANOVA were used to analyze color changes among the assessment times. Spearman`s test was used to evaluate the correlation between the shade guide scores and data from Cielab. </P><P> Results: All methods of color measurement demonstrated any additional effect of second bleaching session on color change, and stable color after 30 days (p < 0.001 for all methods). Both shade guide scales presented low correlation coefficients with &#916;L, and moderate coefficients with &#916;b, Δa, and &#916;E. </P><P> Conclusion: Despite the weak/ moderate correlation among the methods used to measure tooth color, all methods showed similar results of tooth bleaching effectiveness.</P>

scholarly journals Evaluation of post-bleaching hypersensitivity using desensitizing agent before and /or after in-office bleaching: A randomized clinical trial.

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1762
Author(s):  
Silvia Sabry Tawfik ◽  
Mohamed Adel Ezzat Khairy ◽  
Maha Abd Elsalam ElBaz ◽  
Maha Ebrahim Mohamed El korashy
Keyword(s):  
Clinical Trial ◽  
Hydrogen Peroxide ◽  
Secondary Outcome ◽  
Outcome Variable ◽  
Control Group ◽  
Median Score ◽  
Peroxide Bleaching ◽  
Group I ◽  
Before And After ◽  
Shade Guide

Background: Dental bleaching has become one of the most demanded aesthetic procedures as it is very simple and gives fast results that satisfy the patient’s wishes. However, unfortunately, it has the annoying side effect of tooth sensitivity. This clinical trial was designed to evaluate the efficacy of using a desensitizing agent, which was applied during in-office bleaching with 30% HP (hydrogen peroxide). Methods: 36 participants were divided into four groups (N = 9). According to the intended intervention as follows: Group I:—Application of Relief ®Amorphous Calcium Phosphate (ACP) before in-office bleaching; Group II—Application of Relief ®ACP before and after in-office bleaching; Group III—Application of Relief ®ACP after in-office bleaching; and Group IV: placebo was applied before and after in-office bleaching.  Then, three hydrogen peroxide bleaching applications for a total of 45 minutes were performed. The primary outcome variable was hypersensitivity, assessed with (VAS) scale immediately and 24h, 1 week and 1 month after the procedure; while the secondary outcome was teeth shade assessed using the VITAPAN ® classical shade guide. Results: Statistical analysis was done using Kolmogorov-Smirnov, Shapiro-Wilk tests, Kruskal-Wallis test and Dunn’s test. Immediately after bleaching, there was statistically significant distinction in the median pain score between the groups. After 1 day, the ACP gel before and after bleaching group showed the lowest median score, while, the control group confirmed the highest median score. After 2 days, no statistically sizable difference was observed between all groups. The group receiving ACP gel before and after showed the highest change in median of classical shade guide scores while, (ACP gel after) and control group; showed the lowest change. Conclusion: The application of the desensitizing agent prior to and after in–office bleaching was successful in lowering post-bleaching hypersensitivity. Trail Registration: Clinical trial.gov NCT02942082 21/10/2016

scholarly journals Comparative Clinical Study of the Effectiveness of Three Different Bleaching Methods

2009 ◽  
Vol 34 (6) ◽  
pp. 635-641 ◽  
Author(s):  
M. Bizhang ◽  
Y-H. P. Chun ◽  
K. Damerau ◽  
P. Singh ◽  
W. H-M. Raab ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Clinical Study ◽  
Clinical Relevance ◽  
In Vivo Study ◽  
Bleaching Agent ◽  
Carbamide Peroxide ◽  
Over The Counter ◽  
Comparative Clinical Study ◽  
Bleaching Treatment

Clinical Relevance The efficacy of vital bleaching depends on the two aspects—viz, bleaching agent and the bleaching method. Results from this in vivo study show that 10% carbamide peroxide home-bleaching and 15% hydrogen peroxide in-office bleaching were more effective than a 6% hydrogen peroxide home-bleaching over-the-counter product up to three months after completion of the bleaching treatment.

An Incentivized, Workplace Physical Activity Intervention Preferentially Increases Daily Steps in Inactive Employees

2017 ◽  
Vol 32 (3) ◽  
pp. 638-645 ◽  
Author(s):  
M. Ryan Mason ◽  
Melinda J. Ickes ◽  
Marilyn S. Campbell ◽  
Lance M. Bollinger
Keyword(s):  
Physical Activity ◽  
Repeated Measures ◽  
Sedentary Time ◽  
Physical Activity Intervention ◽  
Cost Effective ◽  
Group Iv ◽  
University Employees ◽  
Cohort Design ◽  
Group I ◽  
Repeated Measures Analysis

Although physical activity (PA) is associated with decreased risk of chronic diseases, fewer than half of American adults meet the recommendations for daily PA, in part, due to large amounts of sedentary time in the workplace. Purpose: To determine the efficacy of an incentivized workplace PA intervention. Design: Retrospective cohort design. Setting: Large southeastern university. Participants: Of the 16 588 eligible employees working ≥8 h/wk, 6246 (37.6%) participated and 2206 (13.3%) were included in data analysis. Intervention: Six-week PA intervention with tiered incentives (value: $10.50-$29.00). Measures: Steps/day measured via consumer-grade PA monitors for 1-week pre-, 6-weeks during, and 1-week postintervention. Analysis: Participants were grouped by preintervention PA into 4 groups: <6000 (I); 6000 to 7999 (II); 8000 to 9999 (III); and ≥10 000 (IV) steps/d ( n = 481, 540, 485, and 700, respectively) in accordance with the tiered incentive schedule. Statistical comparisons were made by repeated-measures analysis of variance. Results: During the intervention, participants achieving ≥10 000 steps/d increased by 60%. Groups I, II, and III significantly increased steps/day during the intervention (46%, 24%, and 11%, respectively), which was partially maintained in groups I and II 1-week postintervention. Group IV did not increase steps/day during the intervention and significantly decreased steps/day 1-week postintervention. The estimated cost per participant of this intervention increased with from group I ($55.41) to IV ($71.90). Conclusion: An incentivized, workplace PA intervention preferentially increases PA and is most cost-effective among university employees with low initial PA who may benefit substantially from increased levels of PA.

Effect of Light Activation on Tooth Sensitivity After In-Office Bleaching

2011 ◽  
Vol 36 (3) ◽  
pp. 251-257 ◽  
Author(s):  
S Kossatz ◽  
AP Dalanhol ◽  
T Cunha ◽  
A Loguercio ◽  
A Reis
Keyword(s):  
Analysis Of Variance ◽  
Repeated Measures ◽  
Laser Energy ◽  
Light Emitting Diode ◽  
Light Activation ◽  
Tooth Sensitivity ◽  
Light Emitting ◽  
Repeated Measures Analysis ◽  
Shade Guide ◽  
Effect Of Light

SUMMARY This clinical study evaluated the effects of light-emitting diode (LED)/laser activation on bleaching effectiveness (BE) and tooth sensitivity (TS) during in-office bleaching. Thirty caries-free patients were divided into two groups: light-activated (LA) and non-activated (NA) groups. A 35% hydrogen peroxide gel (Whiteness HP Maxx, FGM Dental Products, Joinville SC, Brazil) was used in three 15-minute applications for both groups. For the LA group, LED/laser energy (Whitening Lase Light Plus, DMC Odontológica, São Carlos SP, Brazil) was used, in accordance with the manufacturer's directions. Two sessions of bleaching were performed at one-week intervals. Color was registered at baseline and after the first and second bleaching sessions using a Vita shade guide. Patients recorded TS on a 0 to 4 scale during bleaching and within the next 24 and 48 hours of each session. BE at recall each week and intensity of TS were evaluated by repeated measures analysis of variance (ANOVA) and Tukey tests (α=0.05). Tooth sensitivity was compared using the Friedman repeated measures analysis of variance by rank and the Wilcoxon sign-ranked test. Faster bleaching was observed for the LA group than for the NA group after the first session (4.8 and 3.8 shade guide units [SGUs]; p=0.0001). However, both techniques were capable of bleaching the same number of SGUs after the second bleaching session (p=0.52). Most of the LA group (53.3%) had sensitivity even 24 hours after each bleaching session, but only 26.6% from the NA group reported TS. The intensity of TS was similar for both groups immediately after bleaching but significantly higher for the LA group 24 hours after each bleaching session (p=0.001). After two bleaching sessions, the use of LED/laser light activation did not improve bleaching speed. Persistent tooth sensitivity and higher tooth sensitivity after 24 hours of bleaching were observed when light activation was used.

scholarly journals Combined Bleaching Technique Using Low and High Hydrogen Peroxide In-Office Bleaching Gel

2016 ◽  
Vol 41 (4) ◽  
pp. 388-396 ◽  
Author(s):  
M Rezende ◽  
L Ferri ◽  
S Kossatz ◽  
AD Loguercio ◽  
A Reis
Keyword(s):  
Hydrogen Peroxide ◽  
Repeated Measures ◽  
Color Change ◽  
Absolute Risk ◽  
Color Stability ◽  
Fisher Exact Test ◽  
High Hydrogen ◽  
Significant Difference ◽  
Shade Guide ◽  
At Home

SUMMARY Objectives: The aim of this study was to evaluate the efficacy, color stability, risk, and intensity of tooth sensitivity (TS) of combined bleaching techniques performed with 20% or 35% hydrogen peroxide for an in-office protocol. Methods: Thirty patients were randomly divided into two groups and submitted to a single 45-minute in-office bleaching session with 35% hydrogen peroxide or 20% hydrogen peroxide. At-home bleaching was performed with 10% carbamide peroxide for two hours daily over the course of two weeks. The color was evaluated with the value-oriented shade guide Vita Classical at different periods up to 12 months after bleaching. Patients recorded the intensity of TS using a five-point verbal scale. Color change data were submitted to a two-way repeated-measures analysis of variance and Tukey test (α=0.05). The absolute risk and intensity of TS were compared with the Fisher exact test and Mann-Whitney test, respectively (α=0.05). Results: On average, an effective and similar whitening of three units in shade guide was observed for both groups, which remained stable for 12 months. When both protocols were compared, the one with hydrogen peroxide 35% showed a higher risk (p=0.02) and intensity of TS (p=0.04). In regard to the TS intensity, no significant difference was observed up to 48 hours after in-office bleaching (p=0.09) and during the at-home bleaching phase of the study (p=0.71). Conclusion: The combined bleaching technique using at-home bleaching associated with in-office bleaching was effective and stable over the course of 12 months, regardless of the concentration of the hydrogen peroxide used for in-office bleaching. However, the protocol with 20% hydrogen peroxide produced lower risk and intensity of TS.

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