scholarly journals Herpes Simplex Esophagitis in Immunocompetent Host: A Case Report

2009 ◽  
Vol 2009 ◽  
pp. 1-3 ◽  
Author(s):  
G. Geraci ◽  
F. Pisello ◽  
G. Modica ◽  
F. Li Volsi ◽  
M. Cajozzo ◽  
...  
Keyword(s):  
Herpes Simplex ◽  
Herpes Simplex Virus Infection ◽  
Acute Onset ◽  
High Dose ◽  
Type I ◽  
Immunocompetent Host ◽  
Immune Disorder ◽  
Viral Culture ◽  
Simplex Virus ◽  
Immunocompetent Patients

Introduction. Herpes simplex esophagitis is well recognized in immunosuppressed subjects, but it is infrequent in immunocompetent patients. We present a case of HSE in a 53-year-old healthy man. Materials and Methods. The patient was admitted with dysphagia, odynophagia, and retrosternal chest pain. An esophagogastroduodenoscopy revealed minute erosive area in distal esophagus and biopsies confirmed esophagitis and findings characteristic of Herpes Simplex Virus infection. Results. The patients was treated with high dose of protonpump inhibitor, sucralfate, and acyclovir, orally, with rapid resolution of symptoms. Discussion. HSV type I is the second most common cause of infectious esophagitis. The majority of symptomatic immunocompetent patients with HSE will present with an acute onset of esophagitis. Endoscopic biopsies from the ulcer edges should be obtained for both histopathology and viral culture. In immunocompetent host, HSE is generally a self-limited condition. Conclusions. HSE should be suspected in case of esophagitis without evident cause, even if the patient is immunocompetent. When the diagnosis of HSE is confirmed, careful history and assessment for an immune disorder such as HIV infection is crucial, to look for underlying immune deficiency.

Acute Monarticular Arthritis Caused by Herpes Simplex Virus Type I

PEDIATRICS ◽  
1983 ◽  
Vol 72 (6) ◽  
pp. 882-883
Author(s):  
GARY RAMAFEDI ◽  
ROBERT L. MULDOON
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Acute Onset ◽  
Etiologic Agent ◽  
Mexican Descent ◽  
Type I ◽  
Oral Lesions ◽  
Acute Arthritis ◽  
Simplex Virus

Numerous viruses have been described as potential causes of acute arthritides.1-3 Recently, herpes simplex virus (HSV) type I has been implicated as a possible etiologic agent in acute arthritis in adults.4-6 The purpose here is to review evidence of the role of herpes viruses in acute arthritis and to report the isolation of HSV from the synovial fluid of a child with arthritis. CASE REPORT A 6-year-old of Mexican descent was admitted to the hospital because of the acute onset of pain and swelling in her light knee. The patients had been well until four days prior to admission when she developed fever and painful oral lesions.

scholarly journals Acute retinal necrosis in a patient with remote severe herpes simplex encephalitis

2019 ◽  
Vol 12 (5) ◽  
pp. e229137 ◽  
Author(s):  
Takaaki Kobayashi ◽  
Poorani Sekar ◽  
Jeffery Meier ◽  
Judy Streit
Keyword(s):  
Herpes Simplex ◽  
Visual Loss ◽  
Acute Onset ◽  
Acute Retinal Necrosis ◽  
High Dose ◽  
Acute Visual Loss ◽  
Intravenous Acyclovir ◽  
Dose Oral ◽  
Simplex Virus ◽  
Hsv 1

A 60-year-old man with a history of severe herpes simplex virus type 1 (HSV-1) encephalitis 2 years prior presented with acute onset of visual loss in the left eye. Dilated funduscopic examination showed retinitis and occlusive vasculitis with retinal necrosis. PCR of the vitreous fluid was positive for HSV-1, and he was diagnosed with acute retinal necrosis (ARN) due to HSV-1. The patient was treated with intravenous acyclovir and intravitreous foscarnet for 2 weeks, followed by high dose oral valacyclovir for 2 weeks. He was subsequently placed on planned life-long suppressive valacyclovir. His case demonstrates that acute visual loss concomitant with or subsequent to HSV-1 encephalitis warrants suspicion of ARN. Prompt therapy with effective antiviral medication is necessary to reduce the risk of sight-threatening complications. Chronic suppression with oral antiviral therapy after ARN is recommended to prevent involvement of the contralateral eye, though there is no consensus on the duration and dosage of antivirals.

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