scholarly journals EEG/MEG Source Imaging: Methods, Challenges, and Open Issues

2009 ◽  
Vol 2009 ◽  
pp. 1-12 ◽  
Author(s):  
Katrina Wendel ◽  
Outi Väisänen ◽  
Jaakko Malmivuo ◽  
Nevzat G. Gencer ◽  
Bart Vanrumste ◽  
...  

We present the four key areas of research—preprocessing, the volume conductor, the forward problem, and the inverse problem—that affect the performance of EEG and MEG source imaging. In each key area we identify prominent approaches and methodologies that have open issues warranting further investigation within the community, challenges associated with certain techniques, and algorithms necessitating clarification of their implications. More than providing definitive answers we aim to identify important open issues in the quest of source localization.

2013 ◽  
Vol 62 (3) ◽  
Author(s):  
Leila SaeidiAsl ◽  
Tahir Ahmad

The ideas underlying the quantitative localization of the sources of the EEG review within the brain along with the current and emerging approaches to the problem. The ideas mentioned consist of distributed and dipolar source models and head models ranging from the spherical to the more realistic based on the boundary and finite elements. The forward and inverse problems in electroencephalography will debate. The inverse problem has non-uniqueness property in nature. More precisely, different combinations of sources can produce similar potential fields occur on the head. In contrast, the forward problem does have a unique solution. The forward problem calculates the potential field at the scalp from known source locations, source strengths and conductivity in the head, and it can be used to solve the inverse problem. In the final part of this paper, we compare the performance of three well–known EEG source localization techniques which applied to the underdetermined (distributed) source localization of the inverse problem. These techniques consist of LORETA, WMN and MN, which comparing by testing localization error.


Author(s):  
Munsif Ali Jatoi ◽  
Nidal Kamel ◽  
Sayed Hyder Abbas Musavi ◽  
José David López

Background: Electrical signals are generated inside human brain due to any mental or physical task. This causes activation of several sources inside brain which are localized using various optimization algorithms. Methods: Such activity is recorded through various neuroimaging techniques like fMRI, EEG, MEG etc. EEG signals based localization is termed as EEG source localization. The source localization problem is defined by two complementary problems; the forward problem and the inverse problem. The forward problem involves the modeling how the electromagnetic sources cause measurement in sensor space, while the inverse problem refers to the estimation of the sources (causes) from observed data (consequences). Usually, this inverse problem is ill-posed. In other words, there are many solutions to the inverse problem that explains the same data. This ill-posed problem can be finessed by using prior information within a Bayesian framework. This research work discusses source reconstruction for EEG data using a Bayesian framework. In particular, MSP, LORETA and MNE are compared. Results: The results are compared in terms of variational free energy approximation to model evidence and in terms of variance accounted for in the sensor space. The results are taken for real time EEG data and synthetically generated EEG data at an SNR level of 10dB. Conclusion: In brief, it was seen that MSP has the highest evidence and lowest localization error when compared to classical models. Furthermore, the plausibility and consistency of the source reconstruction speaks to the ability of MSP technique to localize active brain sources.


Author(s):  
Daniel Rabinovich ◽  
Dan Givoli ◽  
Shmuel Vigdergauz

A computational framework is developed for the detection of flaws in flexible structures. The framework is based on posing the detection problem as an inverse problem, which requires the solution of many forward problems. Each forward problem is associated with a known flaw; an appropriate cost functional evaluates the quality of each candidate flaw based on the solution of the corresponding forward problem. On the higher level, the inverse problem is solved by a global optimization algorithm. The performance of the computational framework is evaluated by considering the detectability of various types of flaws. In the present context detectability is defined by introducing a measure of the distance between the sought flaw and trial flaws in the space of the parameters characterizing the configuration of the flaw. The framework is applied to crack detection in flat membranes subjected to time-harmonic and transient excitations. The detectability of cracks is compared for these two cases.


Author(s):  
Lukas Hecker ◽  
Rebekka Rupprecht ◽  
Ludger Tebartz van Elst ◽  
Juergen Kornmeier

AbstractEEG and MEG are well-established non-invasive methods in neuroscientific research and clinical diagnostics. Both methods provide a high temporal but low spatial resolution of brain activity. In order to gain insight about the spatial dynamics of the M/EEG one has to solve the inverse problem, which means that more than one configuration of neural sources can evoke one and the same distribution of EEG activity on the scalp. Artificial neural networks have been previously used successfully to find either one or two dipoles sources. These approaches, however, have never solved the inverse problem in a distributed dipole model with more than two dipole sources. We present ConvDip, a novel convolutional neural network (CNN) architecture that solves the EEG inverse problem in a distributed dipole model based on simulated EEG data. We show that (1) ConvDip learned to produce inverse solutions from a single time point of EEG data and (2) outperforms state-of-the-art methods (eLORETA and LCMV beamforming) on all focused performance measures. (3) It is more flexible when dealing with varying number of sources, produces less ghost sources and misses less real sources than the comparison methods. (4) It produces plausible inverse solutions for real-world EEG recordings and needs less than 40 ms for a single forward pass. Our results qualify ConvDip as an efficient and easy-to-apply novel method for source localization in EEG and MEG data, with high relevance for clinical applications, e.g. in epileptology and real time applications.


2021 ◽  
Vol 2090 (1) ◽  
pp. 012139
Author(s):  
OA Shishkina ◽  
I M Indrupskiy

Abstract Inverse problem solution is an integral part of data interpretation for well testing in petroleum reservoirs. In case of two-phase well tests with water injection, forward problem is based on the multiphase flow model in porous media and solved numerically. The inverse problem is based on a misfit or likelihood objective function. Adjoint methods have proved robust and efficient for gradient calculation of the objective function in this type of problems. However, if time-lapse electrical resistivity measurements during the well test are included in the objective function, both the forward and inverse problems become multiphysical, and straightforward application of the adjoint method is problematic. In this paper we present a novel adjoint algorithm for the inverse problems considered. It takes into account the structure of cross dependencies between flow and electrical equations and variables, as well as specifics of the equations (mixed parabolic-hyperbolic for flow and elliptic for electricity), numerical discretizations and grids, and measurements in the inverse problem. Decomposition is proposed for the adjoint problem which makes possible step-wise solution of the electric adjoint equations, like in the forward problem, after which a cross-term is computed and added to the right-hand side of the flow adjoint equations at this timestep. The overall procedure provides accurate gradient calculation for the multiphysical objective function while preserving robustness and efficiency of the adjoint methods. Example cases of the adjoint gradient calculation are presented and compared to straightforward difference-based gradient calculation in terms of accuracy and efficiency.


2001 ◽  
Vol 09 (02) ◽  
pp. 359-365 ◽  
Author(s):  
E. C. SHANG ◽  
Y. Y. WANG ◽  
T. F. GAO

To assess the adiabaticity of sound propagation in the ocean is very important for acoustic field calculating (forward problem) and tomographic retrieving(inverse problem). Most of the criterion in the literature is too restrictive, specially for the nongradual ocean structures. A new criterion of adiabaticity is suggested in this paper. It works for nongradual ocean structures such as front and internal solitary waves in shallow-water.


2003 ◽  
Vol 125 (3) ◽  
pp. 609-616 ◽  
Author(s):  
Rodrigo A. Marin ◽  
Placid M. Ferreira

A machining fixture controls position and orientation of datum references (used to define important functional features of the geometry of a mechanical part) relative the reference frame for an NC program. Inaccuracies in fixture’s location scheme result in a deviation of the work part from its nominal specified geometry. For a part to be acceptable this deviation must be within the limits allowed by the geometric tolerances specified. This paper addresses the problem of characterizing the acceptable level of inaccuracy in the location scheme so that the features machined on the part comply with the limits associated with its geometric tolerances. First we solve the “forward problem” that involves predicting the tolerance deviation resulting at a feature from a known set of errors on the locators. However, the paper concentrates on solving the “inverse” problem that involves establishing bounds on the errors of the locators to ensure that the limits specified by geometric tolerances at a feature are not violated.


2005 ◽  
Author(s):  
Olivier Bernus ◽  
Vadim D. Khait ◽  
Marcel Wellner ◽  
Sergey F. Mironov ◽  
Arkady M. Pertsov

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