scholarly journals Integrated MEMS/NEMS Resonant Cantilevers for Ultrasensitive Biological Detection

2009 ◽  
Vol 2009 ◽  
pp. 1-10 ◽  
Author(s):  
Xinxin Li ◽  
Haitao Yu ◽  
Xiaohua Gan ◽  
Xiaoyuan Xia ◽  
Pengcheng Xu ◽  
...  

The paper reviews the recent researches implemented in Chinese Academy of Sciences, with achievements on integrated resonant microcantilever sensors. In the resonant cantilevers, the self-sensing elements and resonance exciting elements are both top-down integrated with silicon micromachining techniques. Quite a lot of effort is focused on optimization of the resonance mode and sensing structure for improvement of sensitivity. On the other hand, to enable the micro-cantilevers specifically sensitive to bio/chemical molecules, sensing materials are developed and modified on the cantilever surface with a self-assembled monolayer (SAM) based bottom-up construction and surface functionalization. To improve the selectivity of the sensors and depress environmental noise, multiple and localized surface modifications are developed. The achieved volume production capability and satisfactory detecting resolution to trace-level biological antigen of alpha-fetoprotein (AFP) give the micro-cantilever sensors a great promise for rapid and high-resoluble detection.

Sensors ◽  
2021 ◽  
Vol 21 (18) ◽  
pp. 6041
Author(s):  
Daniel Mamou ◽  
Lawrence Nsubuga ◽  
Tatiana Lisboa Marcondes ◽  
Simon Overgaard Høegh ◽  
Jeanette Hvam ◽  
...  

Micro-cantilever sensors are a known reliable tool for gas sensing in industrial applications. We have demonstrated the application of cantilever sensors on the detection of a meat freshness volatile biomarker (cadaverine), for determination of meat and fish precise expiration dates. For achieving correct target selectivity, the cantilevers need to be functionalized with a cadaverine-selective binder, based on a cyclam-derivative. Cantilever surface properties such as surface energy strongly influence the binder morphology and material clustering and, therefore, target binding. In this paper, we explore how chemical and physical surface treatments influence cantilever surface, binder morphology/clustering and binding capabilities. Sensor measurements with non-controlled surface properties are presented, followed by investigations on the binder morphology versus surface energy and cadaverine capture. We demonstrated a method for hindering binder crystallization on functionalized surfaces, leading to reproducible target capture. The results show that cantilever surface treatment is a promising method for achieving a high degree of functionalization reproducibility for industrial cantilever sensors, by controlling binder morphology and uniformity.


Langmuir ◽  
2020 ◽  
Vol 36 (41) ◽  
pp. 12087-12087 ◽  
Author(s):  
Yilin Wang ◽  
Shaoyi Jiang ◽  
Zhan Chen ◽  
Shu-Hong Yu ◽  
Gilbert Walker

Zootaxa ◽  
2020 ◽  
Vol 4820 (1) ◽  
pp. 177-185
Author(s):  
TIANQI LAN ◽  
ZHIYUAN YAO ◽  
ABID ALI ◽  
GUO ZHENG ◽  
SHUQIANG LI

The genus Pholcus Walckenaer, 1805 is reported from Pakistan for the first time. Two new species of the Pholcus nenjukovi species-group are described: Pholcus hamuchal Yao & Li sp. nov. (Gilgit Baltistan, male and female) and Pholcus kalam Yao & Li sp. nov. (Khyber Pakhtunkhwa, male and female). Type material is deposited in the Institute of Zoology, Chinese Academy of Sciences (IZCAS) in Beijing, China.


2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
Juntong Qi ◽  
Dalei Song ◽  
Lei Dai ◽  
Jianda Han ◽  
Yuechao Wang

This paper describes recent research on the design, implement, and testing of a new small-scaled rotorcraft Unmanned Aerial Vehicle (RUAV) system—ServoHeli-40. A turbine-powered UAV weighted less than 15 kg was designed, and its major components were tested at the Shenyang Institute of Automation, Chinese Academy of Sciences in Shenyang, China. The aircraft was designed to reach a top speed of more than 20 mps, flying a distance of more than 10 kilometers, and it is going to be used as a test-bed for experimentally evaluating advanced control methodologies dedicated on improving the maneuverability, reliability, as well as autonomy of RUAV. Sensors and controller are all onboard. The full system has been tested successfully in the autonomous mode using the multichannel active modeling controller. The results show that in a real windy environment the rotorcraft UAV can follow the trajectory which was assigned by the ground control station exactly, and the new control method is obviously more effective than the one in the past year's research.


2007 ◽  
Vol 11 (22) ◽  
pp. 1468-1482

Arana Therapeutics Completes Project with CSL. Biotech Capital to Invest $2.2 Million in Generic Health Pty Ltd. Phase III Clinical Trial for “Dual Opioid” Therapy. Beijing Med-Pharm Announces Exclusive Agreement to Market Enablex in China. Genesis Pharmaceuticals Collaborates with the Institute of Microbiology, Chinese Academy of Sciences. NPIL and Merck Collaborate on Cancer Drugs. LifeCell Launches First Stem Cell Center in Tamil Nadu. Japan's Bioventures Today — BCS, Inc. Bio-Rad Launches In2it A1C Analyzer for Point-Of-Care Diabetes Testing.


2018 ◽  
Vol 8 (1) ◽  
pp. 52-56
Author(s):  
Vimlesh Patel

The paper presents a Scientometrics mapping of papers published inJournal of Computer Science and Technology, during 2012 to 2016 as reflected in Web of Science database. It attempts to analyze the growth and development of publications output of Journal of Computer Science and Technologyas reflected. Data for a total of 485 have been downloaded and analysed according to objectives. The study reveals thatThe year wise growth rate revel that highest no. papers published in 2015, No. of Papers: 106 (21.86%) Authorship pattern data reveals that most of the authors like to publish papers in collaborations and most preferred authorship pattern was four author i.e. no. publications for four authors were 125 (25.77 %). The Degree of Collaboration (DC) revel that DC is found highest in 0.95 Co-Authored Publication. The highly prolific authors and their publications revel that Zhang L, published highest numbers of papers (11 nos.), the geographical distribution contributions (International) is revel that Peoples R China is in the top with no. of publications is 371 (76.50%), it is found from institution-wise distribution of papers that highest contributed institutions was Chinese Academy of Sciences with 93 Publications (19.18%) is placed at 1st rank and the average of citations per year (2012-2016) were 205.


Zootaxa ◽  
2012 ◽  
Vol 3267 (1) ◽  
pp. 55
Author(s):  
ZE-QING NIU ◽  
YAN-RU WU ◽  
CHAO-DONG ZHU

The Chinese species of Megachile (Chelostomoda) Michener, 1962, are treated in this paper. Megachile (C.) guangxiensesp. nov. is described and illustrated. A checklist of the known Chinese species, distribution records, and an updated iden-tification key are provided. The type specimens of M. guangxiense are deposited in the Insect Collection of the Institute of Zoology, Chinese Academy of Sciences, Beijing, China (IZCAS, Beijing).


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