scholarly journals Primary Cardiac Angiosarcoma: A Fatal Disease

2009 ◽  
Vol 2009 ◽  
pp. 1-4 ◽  
Author(s):  
L. Antonuzzo ◽  
V. Rotella ◽  
F. Mazzoni ◽  
L. Doni ◽  
D. Bianchini ◽  
...  
Keyword(s):  
Cardiac Tamponade ◽  
Cardiac Mri ◽  
Right Atrium ◽  
Partial Remission ◽  
Fatal Disease ◽  
Cardiac Angiosarcoma ◽  
Progression Of Disease ◽  
The Right ◽  
Oncology Unit ◽  
Work Up

A 42-year-old man with a cardiac tamponade underwent an urgent pericardiotomy that showed tumoral tissue, covering the surface of the right atrium. The tumor was then partially excised, and the histological examination revealed the presence of a moderately-differentiated angiosarcoma. The patient was then referred to the oncology unit and scheduled for a chemotherapy schedule including Epirubicin (60 mg/m2, on days 1 and 2) plus Ifosfamide (2000 mg/m2, on days 1 to 3) and Uromitexan (2000 mg/m2at hours 0, 4, 8 after IFO). All drugs were administered every three weeks. After two cycles, a restaging work-up revealed a partial remission. The treatment was continued for another two cycles. A new evaluation by cardiac MRI evidenced a local and distant (lung) progression of disease. The patient died after three months. This paper confirms that cardiac angiosarcoma is a fatal disease, and the prognosis is usually 6–11 months from time of diagnosis.

Cardiac Angiosarcoma of the Right Atrium with Cardiac Tamponade

2016 ◽  
Vol 12 (5) ◽  
pp. 1-5
Author(s):  
Hirotaka Sato ◽  
Kei Aizawa ◽  
Arata Muraoka ◽  
Hirohiko Akutsu ◽  
Yoshio Misawa
Keyword(s):  
Cardiac Tamponade ◽  
Right Atrium ◽  
Cardiac Angiosarcoma ◽  
The Right

scholarly journals Resection of primary cardiac angiosarcoma infiltrating the right atrioventricular junction and tricuspid valve: a case report

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Lubna Bakr ◽  
Hussam AlKhalaf ◽  
Ahmad Takriti
Keyword(s):  
Surgical Resection ◽  
Tricuspid Valve ◽  
Right Atrium ◽  
Large Mass ◽  
Small Mass ◽  
Malignant Tumours ◽  
Atrioventricular Junction ◽  
Cardiac Angiosarcoma ◽  
Complete Surgical Resection ◽  
The Right

Abstract Background Primary cardiac tumours are extremely rare. Most of them are benign. Sarcomas account for 95% of the malignant tumours. Prognosis of primary cardiac angiosarcoma remains poor. Complete surgical resection is oftentimes hampered when there is extensive tumour involvement into important cardiac apparatus. We report a case of cardiac angiosarcoma of the right atrium and ventricle, infiltrating the right atrioventricular junction and tricuspid valve. Case presentation Initially, a 22-year-old man presented with dyspnoea. One year later, he had recurrent pericardial effusion. Afterwards, echocardiography revealed a large mass in the right atrium, expanding from the roof of the right atrium to the tricuspid valve. The mass was causing compression on the tricuspid valve, and another mass was seen in the right ventricle. Complete resection of the tumour was impossible. The mass was resected with the biggest possible margins. The right atrium was reconstructed using heterologous pericardium. The patient’s postoperative course was uneventful. Postoperative echocardiography showed a small mass remaining in the right side of the heart. Histopathology and immunohistochemistry confirmed the diagnosis of angiosarcoma. The patient underwent adjuvant chemotherapy and radiotherapy later on. He survived for 1 year and 5 days after the surgery. After a diagnosis of lung and brain metastases, he ended up on mechanical ventilation for 48 h and died. Conclusions Surgical resection combined with postoperative chemotherapy and radiotherapy is feasible even in patients with an advanced stage of cardiac angiosarcoma when it is impossible to perform complete surgical resection.

scholarly journals Cardiac Angiosarcoma on the Right Atrium: Two Cases

2012 ◽  
Vol 45 (2) ◽  
pp. 120-123 ◽  
Author(s):  
Won Kyoun Park ◽  
Sung-Ho Jung ◽  
Ju Yong Lim
Keyword(s):  
Right Atrium ◽  
Cardiac Angiosarcoma ◽  
The Right

scholarly journals Hydrodynamic compression of the right atrium: a new echocardiographic sign of cardiac tamponade.

Circulation ◽  
1983 ◽  
Vol 68 (2) ◽  
pp. 294-301 ◽  
Author(s):  
L D Gillam ◽  
D E Guyer ◽  
T C Gibson ◽  
M E King ◽  
J E Marshall ◽  
...  
Keyword(s):  
Cardiac Tamponade ◽  
Right Atrium ◽  
The Right

scholarly journals 479 When 2 rights make a wrong

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
J Tong ◽  
P Joseph Francis ◽  
E Lee
Keyword(s):  
Right Ventricle ◽  
Tricuspid Valve ◽  
Cardiac Mri ◽  
Right Atrium ◽  
Cardiac Myxoma ◽  
Left Ventricular Ejection ◽  
Definitive Treatment ◽  
Transthoracic Echocardiogram ◽  
First Case ◽  
The Right

Abstract Background The presence of an intra-cardiac mass is always a cause for concern, with regards to not only aetiology, but also treatment of complications. We describe a case series of 2 right sided cardiac myxomas, where the first case described an unusual location for tumour occurrence, while the second case provided insights into complications of a cardiac myxoma. Methods The first case involved a 70 year old asymptomatic lady who was referred for an additional heart sound. A transthoracic echocardiogram (TTE) showed a large, mobile 1.5 X 1.2 cm mass, attached to the atrial surface of septal tricuspid valve leaflet, prolapsing in and out of the right sided chambers. This was confirmed on transoesophageal echocardiogram (TEE). Cardiac MRI (magnetic resonance imaging) showed a similar mass attached to the septal tricuspid leaflet with features consistent with a myxoma. She was referred to cardiothoracic surgery, and 2 lobulated tumours arising the septal tricuspid valve and adjacent posterior leaflet were seen. The tumours were resected and a bio-prosthetic tricuspid valve replacement implanted. Histology of the tumours showed myxomatous degeneration of tricuspid valve, consistent with cardiac myxoma. The second case was a 56 year old lady who had dyspnoea, pedal oedema and an elevated jugular venous pulse on examination. A TTE done showed a large 7 X 4 cm mass extending from the right atrium (RA) into the right ventricle (RV). The left ventricular ejection fraction was 35%. Cardiac MRI confirmed the presence of a large mass in the right ventricle that exerted pressure effects on the ventricular septum and RV anterior free wall. Intra-operatively, a large RA mass attached by a stalk to the fossa ovalis was seen. The mass was excised and histology was consistent with cardiac myxoma. A repeat transthoracic echocardiogram done 2 weeks later showed normalisation of the LVEF. See images below for more information. Conclusion While myxomas are the most common benign cardiac tumours, they occur less commonly in the right atrium, and much less so on the tricuspid valve. Clinical manifestations range from being completely asymptomatic, as in the 1st case, to non-specific constitutional symptoms such as fever or general malaise, and to life-threatening complications. These include embolism to the pulmonary circulation, causing sudden death, or to the systemic circulation through an intra-cardiac shunt, causing strokes. This risk is increased if the tumour is large, polypoidal and friable. Large tumours can also cause obstructive symptoms and heart failure. Thus timely diagnosis with multi-modality imaging tools, and definitive treatment with complete resection of the tumour are essential. Continued monitoring for recurrences of the tumour, which can occur in 1-5% of all cases, should be performed as well. Abstract 479 Figure. Right sided cardiac masses

A ticking time bomb: Death caused by acute cardiac tamponade as a result of ruptured aberrant vascular tissue between the right atrium and left lung.

2016 ◽  
Vol 3 (2) ◽  
pp. 55
Author(s):  
Mustafa Demirer ◽  
Ahmet Kupeli ◽  
Cetin Baydar ◽  
Kadir Ceviker ◽  
Abdulkadir Yildiz ◽  
...  
Keyword(s):  
Cardiac Tamponade ◽  
Right Atrium ◽  
Vascular Tissue ◽  
Left Lung ◽  
The Right

scholarly journals Rapidly progressive respiratory failure with multiple halo signs on computed tomography in a patient with primary cardiac angiosarcoma derived from the right atrium: a case report

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Masaoki Saito ◽  
Takeshi Saraya ◽  
Miku Oda ◽  
Toshinori Minamishima ◽  
Ken Kongoji ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cardiac Output ◽  
Respiratory Failure ◽  
Lung Tissue ◽  
Right Atrium ◽  
Cardiac Ct ◽  
Loss Of Consciousness ◽  
Cardiac Angiosarcoma ◽  
Thoracic Ct ◽  
The Right

Abstract Background Primary cardiac neoplasms are extremely rare, with an autopsy incidence of 0.0001–0.003%. Primary cardiac sarcoma is usually derived from the right atrium and it manifests as chest pain, arrhythmia, hemoptysis, dyspnea, and fatigue. The most common target organ for metastasis of primary angiosarcoma is the lungs, but the radiological-pathological correlation has been rarely reported. Case presentation A 38-year-old healthy Japanese man was admitted to our hospital with persistent hemoptysis, exaggerated dyspnea, and two episodes of loss of consciousness in the past 3 months. Non-enhanced thoracic computed tomography (CT) revealed multiple scattered nodules with halo signs. Contrast-enhanced thoracic CT revealed a filling defect in the right atrium, which corresponded to the inhomogeneously enhancing tumor in the right atrium on enhanced electrocardiogram-gated cardiac CT. On day 2, acute respiratory failure occurred, and the patient was placed on mechanical ventilation. The patient was diagnosed with primary cardiac angiosarcoma based on the urgent transcatheter biopsied specimen of the right atrium mass and was treated with intravenous administration of doxorubicin. However, his respiratory status rapidly deteriorated, and he died on day 20. Postmortem biopsy showed that the multiple lung nodules with the halo signs corresponded to the intratumoral hemorrhagic necrosis and peripheral parenchymal hemorrhage in their background, suggesting the fragility of the lung tissue where the tumor had invaded, which caused hemoptysis. Furthermore, two episodes of loss of consciousness occurred probably due to a decreased cardiac output because of a massive tumor occupying the right atrium, recognized as an inhomogeneous centripetal enhancement on enhanced electrocardiogram-gated cardiac CT. Conclusions This case clearly demonstrated that primary cardiac angiosarcoma could expand in the right atrial cavity, which led to a decreased cardiac output resulting in repeated syncope, together with the fragility of lung tissue by tumor invasion, thereby generating a halo sign on thoracic CT.

Cardiac tamponade secondary to Dressler’s syndrome

2021 ◽  
Vol 14 (8) ◽  
pp. e243577
Author(s):  
Stephanie Connaire ◽  
Elena Elchinova ◽  
Chiara Bucciarelli-Ducci ◽  
Philip Campbell
Keyword(s):  
Pericardial Effusion ◽  
Cardiac Tamponade ◽  
Cardiac Mri ◽  
Kidney Injury ◽  
Medical Assessment ◽  
Large Pericardial Effusion ◽  
Assessment Unit ◽  
Loin Pain ◽  
The Right ◽  
High Lactate

A 56-year-old woman presented to hospital with chest pain. Following review and investigations in the medical assessment unit, she was diagnosed with costochondritis and discharged home. She represented 10 days later and was mottled and hypotensive with a high lactate, raised inflammatory markers, an acute kidney injury and bilateral loin pain. A CT of the thorax, abdomen and pelvis showed pleural effusions and a large pericardial effusion with features of cardiac tamponade on subsequent echocardiography. A pericardiocentesis was performed and she was admitted to intensive care for haemofiltration. Once the patient was stable, an inpatient cardiac MRI was requested to further investigate an enhancing pericardium and echo-bright areas in the inferior, inferoseptal and inferolateral walls of the left ventricle demonstrated on echocardiography. The cardiac MRI showed evidence of a recent infarction in the right coronary artery (RCA) territory with pericardial inflammation and a resolved pericardial effusion. Overall, the findings were in keeping with Dressler’s syndrome.

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