scholarly journals A Complex of the Electromagnetic Biosensors with a Nanowired Pickup

2009 ◽  
Vol 2009 ◽  
pp. 1-20 ◽  
Author(s):  
Rostyslav Sklyar
Keyword(s):  
Magnetic Moment ◽  
Magnetic Beads ◽  
Haemoglobin Concentration ◽  
Ionic Channels ◽  
Full Scale ◽  
Passive Mode ◽  
First Order ◽  
Electromagnetic Quantities ◽  
Different Origins ◽  
Additional Excitation

The proposal to measure the biosignal values of different origins with advanced nanosensors of electromagnetic quantities is justified when allowing for superconducting abilities of the devices. They are composed in full-scale arrays. The said arrays can be both implantable into ionic channels of an organism and sheathed on the sources of the electromagnetic emanation. Nanowired head sensors function both in passive mode for picking up the biosignals and with additional excitation of a defined biomedium through the same head (in reverse). The designed variety of bio-nanosensors allow interfacing a variety of biosignals with the external systems, also with a possibility to control the exposure on an organism by artificially created signals. The calculated signals lies in the range of to 5 V, molecules or magnetic beads,  pH, and stream speed  m/s, flow  m/s, and haemoglobin concentration of  . The sensitivity of this micro- or nanoscope can be estimated as (/√Hz) with SNR equal to . The sensitivity of an advanced first-order biogradiometer is equal to 3 fT/√Hz. The smallest resolvable change in magnetic moment detected by this system in the band 10 Hz is 1 fJ/T.

Prediction of First-Order Vessel Responses with Applications to Decision Support Systems

2015 ◽  
Author(s):  
Ulrik D. Nielsen ◽  
Toshio Iseki
Keyword(s):  
Decision Support ◽  
Decision Support Systems ◽  
Support Systems ◽  
Simple Approach ◽  
Full Scale ◽  
Uncertainty Measure ◽  
First Order ◽  
Future Developments ◽  
Vessel Response ◽  
Scale Data

The paper presents a practical and simple approach for making vessel response predictions. Features of the procedure include a) predictions which are scaled so to better agree with corresponding true, future values to be measured at the time the predictions apply at; and b) predictions that are assigned an uncertainty measure to reflect a level of confidence. The approach is tested with full-scale data and the obtained results/predictions agree well with measured values. Potentially, the procedure is therefore very useful in future developments of general decision support systems.

scholarly journals Ubiquitous first-order transitions and site-selective vanishing of the magnetic moment in giant magnetocaloric MnFeSiP alloys detected by Mn55 NMR

2019 ◽  
Vol 100 (10) ◽  
Author(s):  
R. Hussain ◽  
F. Cugini ◽  
S. Baldini ◽  
G. Porcari ◽  
N. Sarzi Amadè ◽  
...  
Keyword(s):  
Magnetic Moment ◽  
First Order ◽  
Site Selective

Spectrochemical Behavior of Carcinogenic Polynuclear Aromatic Hydrocarbons in Biological Systems. Part I: Steady-State Fluorometry of BaP and BeP in Living Cells

1996 ◽  
Vol 50 (11) ◽  
pp. 1345-1351 ◽  
Author(s):  
Ping Chiang ◽  
Kuang-Pang Li ◽  
Tong-Ming Hseu
Keyword(s):  
Aromatic Hydrocarbons ◽  
Normal Liver ◽  
Liver Cells ◽  
Polynuclear Aromatic Hydrocarbons ◽  
Kidney Cells ◽  
Excimer Emission ◽  
First Order ◽  
Polycyclic Aromatic ◽  
Different Origins ◽  
Time Plot

The rates of interactions of polycyclic aromatic hydrocarbons (PAHs) with biological cells studied with fluorescence appear to be different for cells from different origins. The monomer emission of benzo[ a]pyrene (BaP) is enhanced as in liposomes, but more significantly in normal liver cells than in liver cancer cells or kidney cells, and that enhancement is proportional to the amount of cells added. When PAHs are allowed to interact with cells for a certain period of time, metabolism appears to occur. The excimer emission is seen to dissipate continuously as reactions proceed, whereas the monomer emission increases, passes through a maximum, then starts to decrease when excimer emission becomes exhausted. The time plot of the BaP excimer emission in semilogarithmic coordinates indicates that the decrease or the mass transfer of microcrystalline BaP to the cell membrane is a first-order process. Metabolism has been investigated by monitoring the monomer emission. Liver cells have higher monomer emission than the kidney cells in the early stages of interaction, indicating that these cell membranes are more amenable to PAH absorption. Effects of vitamin K3 and radiation have also been investigated.

scholarly journals Rapid detection of cocaine using aptamer-based biosensor on an evanescent wave fibre platform

2018 ◽  
Vol 5 (10) ◽  
pp. 180821 ◽  
Author(s):  
Yong Qiu ◽  
Yunfei Tang ◽  
Bing Li ◽  
Miao He
Keyword(s):  
Evanescent Wave ◽  
Rapid Detection ◽  
Magnetic Beads ◽  
Feasible Solution ◽  
Limit Of Detection ◽  
Significant Loss ◽  
Saturation Model ◽  
First Order ◽  
First Order Kinetics ◽  
Cocaine Detection

The rapid detection of cocaine has received considerable attention because of the instantaneous and adverse effects of cocaine overdose on human health. Aptamer-based biosensors for cocaine detection have been well established for research and application. However, reducing the analytic duration without deteriorating the sensitivity still remains as a challenge. Here, we proposed an aptamer-based evanescent wave fibre (EWF) biosensor to rapidly detect cocaine in a wide working range. At first, the aptamers were conjugated to complementary DNA with fluorescence tag and such conjugants were then immobilized on magnetic beads. After cocaine was introduced to compete against the aptamer-DNA conjugants, the released DNA in supernatant was detected on the EWF platform. The dynamic curves of EWF signals could be interpreted by the first-order kinetics and saturation model. The semi-log calibration curve covered a working range of 10–5000 µM of cocaine, and the limit of detection was approximately 10.5 µM. The duration of the full procedure was 990 s (16.5 min), and the detection interval was 390 s (6.5 min). The specified detection of cocaine was confirmed from four typical pharmaceutic agents. The analysis was repeated for 50 cycles without significant loss of sensitivity. Therefore, the aptamer-based EWF biosensor is a feasible solution to rapidly detect cocaine.

SEMICLASSICAL DESCRIPTION OF ANOMALOUS MAGNETIC MOMENT AND CHIRAL ANOMALY

1992 ◽  
Vol 07 (24) ◽  
pp. 2211-2214
Author(s):  
A. DELLA SELVA ◽  
L. MASPERI
Keyword(s):  
Radiative Correction ◽  
Magnetic Moment ◽  
Anomalous Magnetic Moment ◽  
Chiral Anomaly ◽  
First Order ◽  
Telegdi Equation

It is shown that the same term of a modified Bargmann-Michel-Telegdi equation which explains the first order radiative correction to the electronic magnetic moment accounts for the helicity variation in the infinite momentum limit.

A prediction–evaluation approach to the full-scale emplacement experiment (FE) in Mont Terri

2018 ◽  
Vol 482 (1) ◽  
pp. 39-73 ◽  
Author(s):  
A. Papafotiou ◽  
R. Senger ◽  
C. Li ◽  
A. Singh ◽  
B. Garitte ◽  
...  
Keyword(s):  
Near Field ◽  
Full Scale ◽  
Maximum Temperature ◽  
First Order ◽  
Evaluation Approach ◽  
Hydraulic Behaviour ◽  
Reliability Method ◽  
Term Evaluation ◽  
Mont Terri ◽  
Prediction Evaluation

AbstractA prediction–evaluation approach is developed to assess the propagation of parameter, conceptual and scenario uncertainties in the estimated near-field temperatures of the full-scale emplacement experiment at the Mont Terri rock laboratory. The uncertainty assessment is performed using a three-dimensional thermo-hydraulic numerical model of the full-scale emplacement experiment that represents the emplaced materials and surrounding Opalinus Clay and accounts for heat generation at the heaters. The propagation of parametric uncertainties is assessed using a first-order second-moment method supplemented by Monte Carlo simulations sampling the uncertain parameter space. The risk of uncertain parameters resulting in the failure of the maximum temperature criteria is evaluated with a first-order reliability method. Conceptual and scenario uncertainties are evaluated with deterministic simulation variants. After the conclusion of predictive modelling, a mid-term evaluation of the temperature predictions is performed through a comparison with measurements after 2.5 years of heating. The comparison indicates that the best estimates of temperature agree well with the measurements and that the 95% error bands assessed with parametric uncertainty envelope the measured values in almost all locations. Additional comparison with the measured degree of water saturation and the relative humidity is performed to assess the hydraulic behaviour and set the ground for the long-term evaluation, which will include predictions of the near-field pore pressures.

scholarly journals CD44v6 Defines a New Population of Circulating Tumor Cells Not Expressing EpCAM

Cancers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 4966
Author(s):  
Guillaume Belthier ◽  
Zeinab Homayed ◽  
Fanny Grillet ◽  
Christophe Duperray ◽  
Julie Vendrell ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Cell Sorting ◽  
Magnetic Beads ◽  
Therapeutic Response ◽  
Breast Cancer Patients ◽  
Blood Samples ◽  
Different Origins ◽  
Immune Detection

Circulating tumor cells (CTCs) are promising diagnostic and prognostic tools for clinical use. In several cancers, including colorectal and breast, the CTC load has been associated with a therapeutic response as well as progression-free and overall survival. However, counting and isolating CTCs remains sub-optimal because they are currently largely identified by epithelial markers such as EpCAM. New, complementary CTC surface markers are therefore urgently needed. We previously demonstrated that a splice variant of CD44, CD44 variable alternative exon 6 (CD44v6), is highly and specifically expressed by CTC cell lines derived from blood samples in colorectal cancer (CRC) patients. Two different approaches—immune detection coupled with magnetic beads and fluorescence-activated cell sorting—were optimized to purify CTCs from patient blood samples based on high expressions of CD44v6. We revealed the potential of the CD44v6 as a complementary marker to EpCAM to detect and purify CTCs in colorectal cancer blood samples. Furthermore, this marker is not restricted to colorectal cancer since CD44v6 is also expressed on CTCs from breast cancer patients. Overall, these results strongly suggest that CD44v6 could be useful to enumerate and purify CTCs from cancers of different origins, paving the way to more efficacious combined markers that encompass CTC heterogeneity.

scholarly journals First Order Logic with Inductive Definitions for Model-Based Problem Solving

AI Magazine ◽  
2016 ◽  
Vol 37 (3) ◽  
pp. 69-80 ◽  
Author(s):  
Maurice Bruynooghe ◽  
Marc Denecker ◽  
Miroslaw Truszczynski
Keyword(s):  
Problem Solving ◽  
Answer Set Programming ◽  
Order Logic ◽  
First Order Logic ◽  
Declarative Programming ◽  
First Order ◽  
Inductive Definitions ◽  
Trace Back ◽  
Programming Systems ◽  
Different Origins

In answer-set programming (ASP), programs can be viewed as specifications of finite Herbrand structures. Other logics can be (and, in fact, were) used towards the same end and can be taken as the basis of declarative programming systems of similar functionality as ASP. We discuss here one such logic, the logic FO(ID), and its implementation IDP3. The choice is motivated by notable similarities between ASP and FO(ID), even if both approaches trace back to different origins

Tunable first order transition in La(Fe,Cr,Si)13 compounds: Retaining magnetocaloric response despite a magnetic moment reduction

2019 ◽  
Vol 175 ◽  
pp. 406-414 ◽  
Author(s):  
Luis M. Moreno-Ramírez ◽  
Carlos Romero-Muñiz ◽  
Jia Yan Law ◽  
Victorino Franco ◽  
Alejandro Conde ◽  
...  
Keyword(s):  
Magnetic Moment ◽  
Order Transition ◽  
First Order ◽  
First Order Transition

First-Order Removal Rates for Organic Matter in Full-Scale Waste Stabilization Pond Systems in Northeastern Brazil

2020 ◽  
Vol 231 (10) ◽  
Author(s):  
Matheus Sales Alves ◽  
Fernando José Araújo da Silva ◽  
André Luís Calado Araújo ◽  
Erlon Lopes Pereira
Keyword(s):  
Organic Matter ◽  
Full Scale ◽  
Northeastern Brazil ◽  
Removal Rates ◽  
Stabilization Pond ◽  
First Order ◽  
Waste Stabilization Pond ◽  
Waste Stabilization
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