scholarly journals Folgoration as an Example of Pathergy in a Patient Affected by Pyoderma Gangrenosum and Takayasu's Arteritis

2009 ◽  
Vol 2009 ◽  
pp. 1-3 ◽  
Author(s):  
A. G. Richetta ◽  
S. D'Epiro ◽  
C. Mattozzi ◽  
S. Giancristoforo ◽  
S. Calvieri
Keyword(s):  
Rheumatoid Arthritis ◽  
Ulcerative Colitis ◽  
Pyoderma Gangrenosum ◽  
Monoclonal Gammopathy ◽  
Takayasu’S Arteritis ◽  
Clinical Manifestations ◽  
Neutrophilic Dermatosis ◽  
Minor Trauma ◽  
Takayasu's Arteritis ◽  
Unknown Aetiology

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis of unknown aetiology. Clinical manifestations of PG are characterized by destructive, necrotizing, and noninfective ulceration of the skin. 20–30% of cases are initiated and aggravated by minor trauma or surgery, a phenomenon named pathergy. PG is related to several autoimmune diseases including ulcerative colitis, Crohn's disease, rheumatoid arthritis, and monoclonal gammopathy. The association with Takayasu's arteritis (TA), a chronic inflammatory and stenotic disease of large and medium-sized arteries, is instead less common. We report a case of PG associated with TA that was induced by an accident with folgoration of the skin; in this case the folgoration can be considered as an exemple of Pathergy, that is, a characteristic feature of PG.

scholarly journals Pyoderma Gangrenosum and Erythema Nodosum Revealing Takayasu’s Arteritis

2016 ◽  
Vol 8 (3) ◽  
pp. 354-357 ◽  
Author(s):  
Jonas Loetscher ◽  
Susanna Fistarol ◽  
Ulrich A. Walker
Keyword(s):  
Pyoderma Gangrenosum ◽  
Erythema Nodosum ◽  
Takayasu’S Arteritis ◽  
Skin Lesions ◽  
Takayasu's Arteritis ◽  
Young Females ◽  
Worldwide Distribution ◽  
Asian Populations ◽  
Asian Patients ◽  
Caucasian Female

We report a Caucasian female who presented with simultaneous erythema nodosum and pyoderma gangrenosum due to underlying Takayasu’s arteritis. Takayasu’s arteritis is a chronic large vessel vasculitis of unknown cause. The disease has a worldwide distribution but is most commonly seen in Asian populations. There is a strong predilection for young females. The clinical presentation is variable, but mostly derives from stenosis or occlusion of affected arteries, resulting in claudication and ischemia. Skin manifestations are observed in up to 28% of patients with Takayasu’s arteritis, with erythema nodosum reported more frequently in Caucasians. Pyoderma gangrenosum is more common in Asian patients. This report demonstrates the importance to exclude Takayasu’s arteritis in patients with such skin lesions.

Coexisting Rheumatoid Arthritis and Takayasu's Arteritis: a Case Report and Review of the Literature

2014 ◽  
Vol 21 (6) ◽  
pp. 331
Author(s):  
Hyun-young Kim ◽  
In Suk Min ◽  
Ji Eun Yoo ◽  
Yeonmi Ju ◽  
Pil Hun Song ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Case Report ◽  
Takayasu’S Arteritis ◽  
Takayasu's Arteritis ◽  
Review Of The Literature

scholarly journals Pyoderma gangrenosum and ulcerative colitis in the tropics

2008 ◽  
Vol 41 (6) ◽  
pp. 664-667 ◽  
Author(s):  
Olatunji B. Alese ◽  
David O. Irabor
Keyword(s):  
Rheumatoid Arthritis ◽  
Ulcerative Colitis ◽  
Pyoderma Gangrenosum ◽  
Myeloproliferative Disorders ◽  
Skin Lesions ◽  
Skin Condition ◽  
Wound Dressings ◽  
Systemic Disorder ◽  
Inflammatory Bowel ◽  
The Tropics

Pyoderma gangrenosum is a rare inflammatory skin condition, characterized by progressive and recurrent skin ulceration. There may be rapidly enlarging, painful ulcers with undermined edges and a necrotic, hemorrhagic base. Disorders classically associated with pyoderma gangrenosum include rheumatoid arthritis, inflammatory bowel disease, paraproteinemia and myeloproliferative disorders. There have been some reports of the occurrence of pyoderma gangrenosum in Africa, and in Nigeria, but only one specifically reported pyoderma gangrenosum in association with ulcerative colitis. We report on a 45-year-old man who presented with pyoderma gangrenosum associated with ulcerative colitis; the second report in Nigeria. The skin lesions were managed with daily honey wound dressings. Oral dapsone and prednisolone were started. The frequency of the bloody diarrhea decreased, and was completely resolved by the second week after admission. The ulcers also showed accelerated healing. The goal of therapy is directed towards the associated systemic disorder, if present.

scholarly journals Takayasu's arteritis associated with idiopathic ulcerative colitis.

Gut ◽  
1990 ◽  
Vol 31 (7) ◽  
pp. 831-833 ◽  
Author(s):  
V Sakhuja ◽  
K L Gupta ◽  
D K Bhasin ◽  
N Malik ◽  
K S Chugh
Keyword(s):  
Ulcerative Colitis ◽  
Takayasu’S Arteritis ◽  
Takayasu's Arteritis ◽  
Idiopathic Ulcerative Colitis

scholarly journals Concurrent monoclonal gammopathy and systemic lupus erythematosus in a known case of ulcerative colitis: a case report

2021 ◽  
Author(s):  
mahan shafie ◽  
Alireza hadizadeh ◽  
soheil khalaji ◽  
samaneh parsa
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Ulcerative Colitis ◽  
Case Report ◽  
Clinical Manifestation ◽  
Lupus Erythematosus ◽  
Monoclonal Gammopathy ◽  
Laboratory Tests ◽  
Clinical Manifestations ◽  
Systemic Lupus ◽  
Work Up

Our patient had previously been diagnosed with Ulcerative colitis. the clinical manifestations of the patient along with laboratory tests such as anti-dsDNA and proteinuria were also positive. Therefore, the clinical manifestation was consistent with SLE. in the following work up monoclonal gammopathy in serum electrophoresis was also detected.

Takayasu’s arteritis and ulcerative colitis in a young non-Asian woman: A rare association

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 272-274 ◽  
Author(s):  
Katsinelos ◽  
Tsolkas ◽  
Beltsis ◽  
Chatzimavroudis ◽  
Papaziogas ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Takayasu’S Arteritis ◽  
English Literature ◽  
Asian Woman ◽  
Takayasu's Arteritis ◽  
Asian Ethnicity ◽  
Inflammatory Conditions ◽  
Steroid Dependent ◽  
History Of ◽  
Human Leucocyte Antigens

The association between ulcerative colitis and Takayasu’s arteritis has been well described in patients of Asian ethnicity. We present the third non-Asian case reported in the English literature, of a 37-year-old woman with a 4-year history of Takayasu’s arteritis, who developed idiopathic ulcerative colitis. She was found to carry the human leucocyte antigens HLA-B52 and DR2, which have been previously noted to be associated with these inflammatory conditions, mainly in the Japanese population. Ulcerative colitis was steroid-dependent despite simultaneous administration of mesalazine. Azathioprime achieved remission of both diseases. The possible pathogenic association of the disorders is discussed.

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