scholarly journals Long-Term Outcomes Following Hepatic Resection and Radiofrequency Ablation of Colorectal Liver Metastases

HPB Surgery ◽  
2009 ◽  
Vol 2009 ◽  
pp. 1-8 ◽  
Author(s):  
Andrew McKay ◽  
Katherine Fradette ◽  
Jeremy Lipschitz
Keyword(s):  
Radiofrequency Ablation ◽  
Local Recurrence ◽  
Liver Metastases ◽  
Hepatic Resection ◽  
Colorectal Liver Metastases ◽  
Controlled Trials ◽  
Long Term Outcomes ◽  
Randomized Controlled ◽  
Study Support

Recently some have called for randomized controlled trials comparing RFA to hepatic resection, particularly for patients with only a few small metastases. The objectives were to compare local recurrence and survival following RFA and hepatic resection for colorectal liver metastases. This was a retrospective review of open RFA and hepatic resection for colorectal liver metastases between January 1998 and May 2007. All patients who had RFA were considered to have unresectable disease. 58 patients had hepatic resection and 43 had RFA. A 5-year survival after resection was 43% compared to 23% after RFA. For patients with solitary lesions, a 5-year survival was 48% after resection and 15% after RFA. Sixty percent of patients suffered local recurrences after RFA compared to 7% after hepatic resection. RFA is inferior to resection. The results observed in this study support the consensus that RFA cannot be considered an equivalent procedure to hepatic resection.

Meta-Analysis of Long-Term Outcomes in Patients with Colorectal Liver Metastases Undergoing Hepatectomy with or without Radiofrequency Ablation

2018 ◽  
Vol 84 (12) ◽  
pp. 1913-1923
Author(s):  
Li Long ◽  
Li Wei ◽  
Wu Hong
Keyword(s):  
Radiofrequency Ablation ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Meta Analysis ◽  
Disease Free Survival ◽  
Medical Subject Headings ◽  
Long Term Outcomes ◽  
Hazard Ratios ◽  
Long Term Prognosis

This meta-analysis aimed to compare the long-term prognosis of patients with colorectal liver metastases undergoing liver resection (LR) with or without radiofrequency ablation (RFA). A systematic search was performed using both medical subject headings and truncated word searches to identify all comparative studies published on this topic. The primary outcomes were postoperative overall survival (OS) and disease-free survival (DFS). Pooled hazard ratios (HR) with 95 per cent confidence intervals (95% CI) were calculated. A total of 10 studies which included 3900 patients were finally enrolled in the meta-analysis. Patients treated by LR gained better OS (HR: 2.07, 95% CI: 1.82–2.37) and DFS (HR: 1.91, 95% CI: 1.70–2.15) than those patients treated by LR 1 RFA, after pooling unadjusted HRs from the 10 studies. Five studies provided the data of adjusted HR. The pooled results showed that patients in the LR 1 RFA group had shorter OS (HR: 1.66, 95% CI: 1.18–2.32, P = 0.004) but similar DFS (HR: 1.36, 95% CI: 0.99–1.88) compared with patients in the LR group. Our meta-analysis showed that colorectal liver metastases patients who underwent LR gained better long-term outcomes compared with patients undergoing LR 1 RFA. However, after adjusting confounders, LR 1 RFA achieved comparable DFS with LR alone.

Impact of the C-reactive protein to albumin ratio on long-term outcomes after hepatic resection for colorectal liver metastases

2017 ◽  
Vol 214 (4) ◽  
pp. 752-756 ◽  
Author(s):  
Koichiro Haruki ◽  
Hiroaki Shiba ◽  
Takashi Horiuchi ◽  
Taro Sakamoto ◽  
Takeshi Gocho ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Hepatic Resection ◽  
Colorectal Liver Metastases ◽  
C Reactive Protein ◽  
Long Term Outcomes ◽  
Albumin Ratio ◽  
Reactive Protein

scholarly journals Preoperative peripheral blood neutrophil count predicts long-term outcomes following hepatic resection for colorectal liver metastases

2017 ◽  
Vol 13 (5) ◽  
pp. 3688-3694 ◽  
Author(s):  
Koichiro Haruki ◽  
Hiroaki Shiba ◽  
Yuki Fujiwara ◽  
Kenei Furukawa ◽  
Tomonori Iida ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Hepatic Resection ◽  
Neutrophil Count ◽  
Peripheral Blood ◽  
Colorectal Liver Metastases ◽  
Blood Neutrophil ◽  
Long Term Outcomes ◽  
Peripheral Blood Neutrophil

scholarly journals A comparison of long-term outcomes in patients with colorectal liver metastases undergoing complete(R0) and microscopically incomplete(R1) hepatic resection

HPB ◽  
2016 ◽  
Vol 18 ◽  
pp. e737-e738
Author(s):  
J. Skipworth ◽  
A. Haswell ◽  
D. Raptis ◽  
P. Athanasopolous ◽  
B. Davidson ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Hepatic Resection ◽  
Colorectal Liver Metastases ◽  
Long Term Outcomes
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