scholarly journals Fosfluconazole for Antifungal Prophylaxis in Very Low Birth Weight Infants

2009 ◽  
Vol 2009 ◽  
pp. 1-3
Author(s):  
Daijiro Takahashi ◽  
Tomohiko Nakamura ◽  
Reiko Shigematsu ◽  
Miyu Matsui ◽  
Shunsuke Araki ◽  
...  
Keyword(s):  
Central Venous Catheter ◽  
Fungal Infection ◽  
Invasive Fungal Infection ◽  
Very Low Birth Weight ◽  
Case Series ◽  
Venous Catheter ◽  
Antifungal Prophylaxis ◽  
Central Venous ◽  
Vlbw Infants ◽  
Case Series Study

We conducted a retrospective case series study to evaluate the safety of fosfluconazole prophylaxis for preventing invasive fungal infection in VLBW infants with a central vascular access. Fosfluconazole was administered intravenously at a dose of 6 mg/kg everyday during which time a central venous catheter was placed. A total of 23 infants met the criteria for enrollment in our study. No cases of fungal infection were detected during the central venous catheter placement in the group. None of the infants had an elevatedβ-D-glucan, and all of them were still alive at discharge. Regarding the liver and renal function, no statistically significant differences were observed before and at the end of fosfluconazole prophylaxis. The results of this study demonstrate that fosfluconazole prophylaxis in preventing invasive fungal infection was well tolerated by VLBW infants. This is a first report to describe antifungal prophylaxis using fosfluconazole for VLBW infants.

Use of Central Venous Catheter and Peripheral Venous Catheter as Risk Factors for Nosocomial Bloodstream Infection in Very-Low-Birth-Weight Infants

2010 ◽  
Vol 31 (4) ◽  
pp. 395-401 ◽  
Author(s):  
Christine Geffers ◽  
Anne Gastmeier ◽  
Frank Schwab ◽  
Katrin Groneberg ◽  
Henning Rüden ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Central Venous Catheter ◽  
Bloodstream Infection ◽  
Very Low Birth Weight ◽  
Venous Catheter ◽  
Central Venous ◽  
Vlbw Infants ◽  
Peripheral Venous Catheter

Objective.To describe the relationship between the use of central and peripheral venous catheters and the risk of nosocomial, primary, laboratory-confirmed bloodstream infection (BSI) for neonates with a birth weight less than 1,500 g (very-low-birth-weight [VLBW] infants).Methods.Cox proportional hazard regression analysis with time-dependent variable was used to determine the risk factors for the occurrence of BSI in a cohort of VLBW infants. We analyzed previously collected surveillance data from the German national nosocomial surveillance system for VLBW infants. All VLBW infants in 22 participating neonatal departments who had a complete daily record of patient information were included.Results.Of 2,126 VLBW infants, 261 (12.3%) developed a BSI. The incidence density for BSI was 3.3 per 1,000 patient-days. The multivariate analysis identified the following significant independent risk factors for BSI: lower birth weight (hazard ratio [HR], 1.1–2.2), vaginal delivery (HR, 1.5), central venous catheter use (HR, 6.2) or peripheral venous catheter use (HR, 6.0) within 2 days before developing BSI, and the individual departments (HR, 0.0–4.6).Conclusions.After adjusting for other risk factors, use of peripheral venous catheter and use of central venous catheter were significantly related to occurrence of BSI in VLBW infants.

scholarly journals Guide-wire replacement of a mini-midline catheter with a central venous catheter: A retrospective study on 63 cases

2020 ◽  
pp. 112972982094406
Author(s):  
Lucio Brugioni ◽  
Elisabetta Bertellini ◽  
Mirco Ravazzini ◽  
Marco Barchetti ◽  
Andrea Borsatti ◽  
...  
Keyword(s):  
Central Venous Catheter ◽  
Guide Wire ◽  
Case Series ◽  
Venous Catheter ◽  
Venous Access ◽  
Late Complications ◽  
Central Catheter ◽  
Central Venous ◽  
Single Lumen ◽  
Thrombotic Complications

Background: Achieving a reliable venous access in a particular subset of patients and/or in emergency settings can be challenging and time-consuming. Furthermore, many hospitalized patients do not meet the criteria for central venous catheter positioning, unless an upgrade of the treatment is further needed. The mini-midline catheter has already showed to be reliable and safe as a stand-alone device, since it is easily and rapidly inserted and can indwell up to 1 month. Methods: In this further case series, we retrospectively evaluated data from 63 patients where a previously inserted mini-midline catheter was upgraded to a central venous catheter (the devices inserted in the arm replaced by peripherally inserted central catheter and others inserted “off-label” in the internal jugular replaced by single lumen centrally inserted central catheter), being used as introducer for the Seldinger guidewire. Results: The guidewire replacement was been made even early (after 1 day) or late (more than 10 days), usually following a need for an upgrade in treatment. No early or late complications were reported. Conclusion: According to the preliminary data we collected, this converting procedure seems to be feasible and risk-free, since neither infectious nor thrombotic complications were reported.

scholarly journals USE OF CLINICAL INDICATORS IN THE EVALUATION OF PREVENTION AND CONTROL PRACTICES FOR BLOODSTREAM INFECTION

2015 ◽  
Vol 24 (4) ◽  
pp. 1018-1026 ◽  
Author(s):  
Francisca Jane Gomes de Oliveira ◽  
Joselany Afio Caetano ◽  
Viviane Martins da Silva ◽  
Paulo César de Almeida ◽  
Andrea Bezerra Rodrigues ◽  
...  
Keyword(s):  
Central Venous Catheter ◽  
Bloodstream Infection ◽  
Prevention And Control ◽  
Compliance Rate ◽  
Case Series ◽  
Venous Catheter ◽  
Central Venous ◽  
Clinical Indicators ◽  
And Control ◽  
Catheter Related Bloodstream Infection

ABSTRACT The aim of this study was to evaluate the compliance of the implemented prevention and control practices for central venous catheter-related bloodstream infection, through clinical indicators. An observational study, with a quantitative approach, was conducted. The case series was based on 2064 evaluations, conducted through direct observation and medical records, using a manual for evaluating the quality of cross-infection control practices. The results showed that the indicator for the registrations of the insertion and dwell time of the catheter had the highest overall compliance rate (62.5%). The indicator related to hand hygiene, on the other hand, showed a null overall compliance rate. Strategies must be developed to ensure adherence to the prevention and control practices for central venous catheter-related bloodstream infection and periodic evaluations of working conditions must be implemented, in order to raise compliance rates.

scholarly journals The Use Of Polyurethane Transparent Film In Indwelling Central Venous Catheter

2010 ◽  
Vol 18 (6) ◽  
pp. 1212-1220 ◽  
Author(s):  
Renata Cristina de Campos Pereira Silveira ◽  
Fernanda Titareli Merizio Martins Braga ◽  
Livia Maria Garbin ◽  
Cristina Maria Galvão
Keyword(s):  
Central Venous Catheter ◽  
Case Series ◽  
Venous Catheter ◽  
Skin Toxicity ◽  
Transparent Film ◽  
Exit Site ◽  
Central Venous ◽  
Hematopoietic Stem ◽  
Gauze Dressing ◽  
Sterile Gauze

Dressing is an intervention aimed to prevent infection in central venous catheter. This study aimed to analyze the frequency of catheter-related infection and skin toxicity in the use of transparent film in Hickman’s catheter in patients who underwent allogeneic hematopoietic stem cell transplantation. A case series with 10 cases was carried out. Due to the presence of exudate on the average for 12 days, sterile gauze dressing was used for 12.9 days (average). Transparent film was used, on average, for 15.1 days. Catheters were precociously removed due to infection in four cases. The highest degree of skin toxicity occurred in a case that used gauze dressing and in three cases with film. The transparent film permitted visualization of the exit site of the catheter and changes with longer intervals.

Percutaneous central venous catheter use in the very low birth weight neonate

1995 ◽  
Vol 154 (2) ◽  
pp. 145-147
Author(s):  
P. A. Cairns ◽  
D. C. Wilson ◽  
B. G. McClure ◽  
H. L. Halliday ◽  
M. McReid
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Central Venous Catheter ◽  
Very Low Birth Weight ◽  
Venous Catheter ◽  
Central Venous ◽  
Birth Weight Neonate ◽  
Percutaneous Central Venous Catheter

scholarly journals Late onset sepsis and intestinal bacterial colonization in very low birth weight infants receiving long-term parenteral nutrition

2011 ◽  
Vol 44 (4) ◽  
pp. 447-450 ◽  
Author(s):  
Priscila Castro Cordeiro Fernandes ◽  
Elias Jose Oliveira von Dolinger ◽  
Vânia Olivetti Steffen Abdallah ◽  
Daiane Silva Resende ◽  
Paulo Pinto Gontijo Filho ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Central Venous Catheter ◽  
Parenteral Nutrition ◽  
Very Low Birth Weight ◽  
Late Onset ◽  
Venous Catheter ◽  
Central Venous ◽  
Low Birth Weight Infants ◽  
Late Onset Sepsis

INTRODUCTION: The purpose of this study was to establish the late onset sepsis (LOS) rate of our service, characterize the intestinal microbiota and evaluate a possible association between gut flora and sepsis in surgical infants who were receiving parenteral nutrition (PN). METHODS: Surveillance cultures of the gut were taken at the start of PN and thereafter once a week. Specimens for blood culture were collected based on clinical criteria established by the medical staff. The central venous catheter (CVC) tip was removed under aseptic conditions. Standard laboratory methods were used to identify the microorganisms that grew on cultures of gut, blood and CVC tip. RESULTS: 74 very low birth weight infants were analyzed. All the infants were receiving PN and antibiotics when the gut culture was started. In total, 21 (28.4%) infants experienced 28 episodes of LOS with no identified source. Coagulase negative staphylococci were the most common bacteria identified, both in the intestine (74.2%) and blood (67.8%). All infections occurred in patients who received PN through a central venous catheter. Six infants experienced episodes of microbial translocation. CONCLUSIONS: In this study, LOS was the most frequent episode in neonates receiving parenteral nutrition who had been submitted to surgery; 28.6% of this infection was probably a gut-derived phenomenon and requires novel strategies for prevention.

scholarly journals Central Venous Catheter–Related Bacteremia Due toTsukamurellaSpecies in the Immunocompromised Host: A Case Series and Review of the Literature

2002 ◽  
Vol 35 (7) ◽  
pp. e72-e77 ◽  
Author(s):  
M. A. Schwartz ◽  
S. R. Tabet ◽  
A. C. Collier ◽  
C. K. Wallis ◽  
L. C. Carlson ◽  
...  
Keyword(s):  
Central Venous Catheter ◽  
Case Series ◽  
Venous Catheter ◽  
Immunocompromised Host ◽  
Review Of The Literature ◽  
Central Venous
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