scholarly journals Latent Lymphocytic Enterocolitis Associated with Celiac Disease Manifesting after Resection for Colon Cancer: Case Report and Review of the Literature

2008 ◽  
Vol 22 (9) ◽  
pp. 771-773 ◽  
Author(s):  
Vikram Tangri ◽  
David K Driman ◽  
Nilesh Chande

Lymphocytic colitis, a cause of chronic watery diarrhea, is histologically characterized by increased intraepithelial lymphocytosis. Studies have associated this disorder with celiac disease, although there are no reports of patients with both lymphocytic colitis and colon cancer. The present case report describes a patient with lymphocytic colitis, which manifested five years after he presented with a cecal adenocarcinoma, and three years following a diagnosis of celiac disease. Pathological review of his initial resection specimen demonstrated lymphocytic enterocolitis, indicating a five-year latency in the presentation of this disease.

2005 ◽  
Vol 66 (2) ◽  
pp. 86-87
Author(s):  
Keizo Yoneda ◽  
Keiji Suzuki ◽  
Kenji Katumata ◽  
Tatehiko Wada ◽  
Fumiaki Katou ◽  
...  

2014 ◽  
Vol 03 (12) ◽  
pp. 669-673
Author(s):  
Helena Devesa ◽  
Luísa Pereira ◽  
Álvaro Gonçalves ◽  
Telma Brito ◽  
Teresa Almeida ◽  
...  

1996 ◽  
Vol 10 (7) ◽  
pp. 436-439 ◽  
Author(s):  
Hugh James Freeman

Lymphocytic colitis is a form of microscopic colitis usually characterized by watery diarrhea and often associated with biopsy-defined celiac disease. Two patients with lymphocytic colitis and normal small intestinal biopsies who were administered 40 g of added dietary gluten for four consecutive weeks are presented. Small intestinal biopsies from multiple sites in the proximal small bowel were done after three and four weeks to determine whether pathological changes in latent celiac disease could be induced in these patients with a high gluten-containing diet. In addition, colorectal biopsies were done to determine whether the colitis was sensitive to oral gluten. No alterations in the small intestinal biopsies were detected in either patient and no changes occurred in colitis severity. Although microscopic forms of colitis have been linked to celiac disease, this study indicates that lymphocytic colitis is a heterogeneous clinicopathological disorder that, in some patients, is independent of any gluten-induced intestinal pathological changes.


1999 ◽  
Vol 13 (4) ◽  
pp. 347-350 ◽  
Author(s):  
Hugh J Freeman

A 66-year-old woman was seen repeatedly over a decade to remove recurrent colonic adenomas and investigate episodes of watery diarrhea. Although the diarrhea was believed to be due to lymphocytic colitis, she developed weight loss, hypoproteinemia and hyposplenism that resulted in further studies, specifically to exclude celiac disease. Small intestinal biopsies, however, showed severely ‘flattened’ villous architecture with trichrome-positive subepithelial collagenous deposits, characteristic of collagenous sprue. Antiendomysial antibodies, known serological markers of celiac disease, were also detected. While collagenous sprue has been considered a distinct small intestinal disorder, the constellation of clinical and pathological findings in this patient suggests a close link with adult celiac disease.


2012 ◽  
Vol 81 (2) ◽  
pp. 112-113
Author(s):  
Chika Kusano ◽  
Takuji Gotoda ◽  
Syuntaro Mukai ◽  
Yasuo Yamanaka ◽  
Akio Sugita ◽  
...  

2015 ◽  
Vol 5 (3) ◽  
pp. 38
Author(s):  
M. H. Fridman ◽  
V. I. Gilinskiy ◽  
E. Yu. Klimov ◽  
E. Yu. Zorina ◽  
G. N. Khrykov

In Vivo ◽  
2020 ◽  
Vol 34 (6) ◽  
pp. 3413-3419
Author(s):  
SAWAKO HIROI ◽  
MASASHI MIGUCHI ◽  
SATOSHI IKEDA ◽  
HIDEKI NAKAHARA ◽  
KATSUNORI SHINOZAKI ◽  
...  

2013 ◽  
Vol 33 (3) ◽  
pp. 894-897
Author(s):  
Mehmet Güney ŞENOL ◽  
Serkan DEMİR ◽  
Mustafa Tansel KENDİRLİ ◽  
Bora GÜLAY ◽  
Fatih ÖZDAĞ

2013 ◽  
pp. 254-258
Author(s):  
Antonio Carroccio ◽  
Tiziana Catalano ◽  
Marilena Fiorino ◽  
Accursia Bongiovì ◽  
Giuseppe Napoli ◽  
...  

Introduction: Collagenous colitis (CC) is a rare condition that is known to complicate inflammatory bowel diseases, but its relationship with celiac disease (CD) is more controversial. Aims: To report a case of CC that developed in a patient with CD and was manifested by rectal erosions at onset. Case report: A 46-year-old woman was diagnosed with CD and placed on a gluten-free diet. After an initial phase of improvement, her diarrhea resumed, and she began to lose weight. Despite strict adherence to the diet, the patient's diarrhea worsened. One year after diagnosis, colonoscopy was performed and mucosal biopsies were collected, but the findings were inconclusive. Two months later, the previously watery diarrhea became bloody, and a second colonoscopy was performed. Histological examination of the biopsy specimens revealed rectal erosions and CC. The patient was treated with oral prednisone plus mesalazine for 6 weeks, and her symptoms immediately disappeared. Mesalazine was continued, and the prednisone was then gradually replaced with budesonide. Six months after the CC diagnosis, the patient was asymptomatic, and a second colonoscopy revealed no macroscopic or microscopic signs of CC. She continues to take mesalazine and budesonide. An attempt to taper the dosage of the latter drug from 6 to 3 mg/day caused the reappearance of the diarrhea. Conclusion: CC is rarely associated to CD and can cause bloody diarrhea. Excellent results were obtained in this case with prednisone plus mesalazine followed by maintenance therapy with budesonide plus mesalazine.


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