scholarly journals Organ-Preserving Surgery for Penile Carcinoma

2008 ◽  
Vol 2008 ◽  
pp. 1-7 ◽  
Author(s):  
Francisco E. Martins ◽  
Raul N. Rodrigues ◽  
Tomé M. Lopes

Introduction. Penile carcinoma has traditionally been treated by either surgical amputation or radical radiotherapy, both associated with devastating anatomical, functional, and psychological impact on the patient's life. Innovative surgical techniques have focused on penile preservation in well-selected patients to minimize physical disfigurement and consequently maximize quality of life. The objective of this article is to define the current status of these organ-preserving surgical options for penile carcinoma.Materials and Methods. An extensive review of the Pubmed literature was performed to find articles discussing only reconstructive surgery which have contributed significantly to change traditional, frequently mutilating treatments, to develop less disfiguring surgery, and to improve patients' quality of life over the last two decades.Results. Several articles were included in this analysis in which a major contribution to the change in therapy was thought to have occurred and was documented as beneficial. Some articles reported novel techniques of less-mutilating surgery involving different forms of glans reconstruction with the use of flaps or grafts. The issue of safe surgical margins was also addressed.Conclusion. The development of less-disfiguring techniques allowing phallus preservation has reduced the negative impact on functional and cosmetic outcomes of amputation without sacrificing oncological objectives in appropriately selected patients based on stage, grade, and location of the tumour. Until more prospective studies are available and solid evidence is documented, organ preservation should be offered with caution.

2020 ◽  
pp. 254-259
Author(s):  
A. A. Gorpenko ◽  
V. D. Chuprinin ◽  
N. A. Buralkin ◽  
A. S. Safronova

Introduction. Adenomyosis has a significantly negative impact on women’s quality of life, causing abnormal uterine bleeding, dysmenorrhea, and chronic pelvic pain and low quality of life. There are no single theory of pathogenesis, unique prognosis and diagnostic markers for adenomyosis. The definitive treatment for adenomyosis is hysterectomy but is not appropriate for patients who wish to preserve their fertility. In this article presents data about etiology, classification, pathogenesis, clinical manifestation and surgical techniques for the treatment of adenomyosis published in medical–scientific databases.Materials and methods. The review includes data from foreign and Russian articles published in the Pubmed journals on this topic.Results. There are a lot of surgical approaches for adenomyosis; however, there is no any universal approach and management guideline for these patients.Conclusion. Adenomyosis – if multifactorial disease. There is no single pathogenesis theory. The clinical picture of adenomyosis varies from asymptomatic to severe pain. The management of adenomyosis is complex and should guide personally for each patient. All techniques and options should be considered and discussed with the patient.


2021 ◽  
Vol 12 (1) ◽  

Background: Acne Vulgaris is a rife and chronic dermal disorder, which commonly occurs in pubescent. This disease is characterized by the emergence of comedones, papules, pustules, nodules, or cysts which results from obstruction and inflammation of pilosebaceous units. Objective: To finding out the prevalence and psychological impact of acne on the quality of life in undergraduate medical students of Lahore, Pakistan. Methodology: A cross-sectional study was conducted during the month of October 2020, 291 among undergraduate medical students from eight medical colleges of Lahore, selected through simple random sampling, on both male and female undergraduate medical students. To assist them; they were given a simple grading criterion to self-diagnose their current acne severity and quality of life was evaluated by Cardiff Acne Disability Index. Data were analyzed by using SPSS version 22. Results: A total of 213 (73.2%) prevalence of acne was found among the participants who responded (291). No significant relation between acne severity and gender was found (p=0.151). There was no association between CADI score and gender (p=0.366). However, a significant correlation was found between CADI score and acne severity (p=0.000). In the population studied, 4.7% showed their acne severely impacting their quality of life, 27.7% have moderate, 58.7% have mild and 8.9% have no impact at all. Conclusion: High Prevalence rate of acne and its significant negative impact on QOL indicates that it is a very common dermatological disorder. Effective interventions can make substantial contributions to derogate the impact of acne severity on QOL.


2021 ◽  
pp. 000348942110506
Author(s):  
Gemma M. Clunie ◽  
Catherine Anderson ◽  
Matthew Savage ◽  
Catherine Hughes ◽  
Justin W. G. Roe ◽  
...  

Objectives: To investigate how the symptoms of mucus and cough impact adults living with laryngotracheal stenosis, and to use this information to guide future research and treatment plans. Methods: A survey was developed with the support of patient advisors and distributed to people suffering with laryngotracheal stenosis. The survey comprised 15 closed and open questions relating to mucus and cough and included the Leicester Cough Questionnaire (LCQ). Descriptive statistics, X2 and thematic analyses were completed. Results: In total, 641 participants completed the survey, with 83.62% (n = 536) reporting problems with mucus; 79% having daily issues of varying severity that led to difficulties with cough (46.18%) and breathing (20.90%). Mucus affected voice and swallowing to a lesser degree. Respondents described a range of triggers; they identified smoky air as the worst environmental trigger. Strategies to manage mucus varied widely with drinking water (72.26%), increasing liquid intake in general (49.35%) and avoiding or reducing dairy (45.32%) the most common approaches to control symptoms. The LCQ showed a median total score of 14 (interquartile range 11-17) indicative of cough negatively affecting quality of life. Thematic analysis of free text responses identified 4 key themes—the Mucus Cycle, Social impact, Psychological impact, and Physical impact. Conclusion: This study shows the relevance of research focusing on mucus and cough and its negative impact on quality of life, among adults with laryngotracheal stenosis. It demonstrates the inconsistent advice and management strategies provided by clinicians for this issue. Further research is required to identify clearer treatment options and pathways.


2015 ◽  
Vol 62 (3) ◽  
pp. 294-297
Author(s):  
A. Zamfir-Chiru-Anton ◽  
◽  
D.C. Gheorghe ◽  

The authors review the techniques described for the surgical treatment of the tonsils. Each new method has its own advantages and disadvantages. The difference can be evaluated by studying the intraoperative blood loss and safety of the procedure. Also, the postoperative complications and quality of life can be used as an adjunct to objectively appreciate the different surgical techniques. There is no literature consensus about the superiority of one technique over the other. Multiple studies brought multiple significant results. It is also hard to evaluate the entire panel of surgical methods described concomitantly. The experience of one surgeon and his/her mastering of a certain technique is the actual cause of so many surgical options still in use for tonsil treatment in children.


2020 ◽  
Vol 18 (1) ◽  
pp. 33-39
Author(s):  
Mohammad Golam Mowla Chowdhury ◽  
Isteaq Ahmed Shameem ◽  
Md Sajid Hasan

Objective: The objective of this article is to provide an overview of the current concepts of organ-preserving procedures for penile cancer, and describe some of their indications, results and associated complications. Methods: An extensive search of review articles of the Pubmed literature was performed to find articles discussing only organ sparing reconstructive surgery which have contributed significantly to change traditional, frequently mutilating treatments, to develop less disfiguring surgery, and to improve patients’ quality of life over the last two decades. Results: A large number of articles were included in this study in which a major contribution to the change in the treatment was thought to have occurred and was documented as beneficial. Some articles reported novel techniques of less-mutilating surgery involving different forms of glans reconstruction with the use of flaps or grafts. The issue of safe surgical margins was also addressed. Conclusion: In highly selected cases of penile carcinoma, organ preserving techniques allowing phallus preservation has reduced the negative impact on functional and cosmetic outcomes of amputation without sacrificing oncological objectives based on stage, grade, and location of the tumour. Until more prospective studies are available and strong evidence is documented, organ preservation should be offered with caution. Bangladesh Journal of Urology, Vol. 18, No. 1, Jan 2015 p.33-39


BMJ Leader ◽  
2020 ◽  
pp. leader-2019-000199
Author(s):  
Charleen Singh ◽  
Caitlin Loseth ◽  
Noordeen Shoqirat

The number of women entering medicine significantly increased over the last decades. Currently, over half of the medical students are women but less than half are applying to surgery and even less go on to surgical specialties. Even fewer women are seen in leadership roles throughout the profession of surgery and surgical residency. Our purpose of the literature review is to identify any themes, which would provide insight to the current phenomenon. We used the Preferred Reporting Items for Systemic Reviews and Meta-Analyses method for a systematic review of the literature over a 20-year period (1998–2018). Five broad themes were identified: education and recruitment, career development, impact of/on life around the globe and surgical subspecialties as areas of barriers for women entering or considering surgery. The systematic review suggests there are opportunities to improve and encourage women entering the profession of surgery as well as the quality of life for surgeons. Creating systems for mentorship across programmes, having policies to support work–life balance and recognising surgical training overlaps with childbearing years are key opportunities for improvement. Improving the current status in surgery will require direction from leadership.


Author(s):  
Germina-Alina Cosma ◽  
Alina Chiracu ◽  
Amalia Raluca Stepan ◽  
Marian Alexandru Cosma ◽  
Marian Costin Nanu ◽  
...  

The aim of this study was to analyze athletes’ quality of life during the COVID-19 pandemic. The study involved 249 athletes between 15 and 35 of age, M = 21.22, SD = 5.12. The sample was composed of eight Olympic Games medalists, three European medalists, 67 international medalists, and 63 national medalists. The instruments used were: (1) COVID-19 Anxiety Scale, (2) Athlete Quality of Life Scale, (3) Impact of Pandemic on Athletes Questionnaire, and (4) International Personality Item Pool (IPIP Anxiety, Depression, and Vulnerability Scales). The results indicate significant differences in COVID-19 anxiety depending on the sport practiced, F (9239) = 3.81, p < 0.01, showing that there were significant differences between sports. The negative impact of the COVID-19 pandemic mediates the relationship between trait anxiety and the athletes’ quality of life. The percentage of mediation was 33.9%, and the indirect effect was −0.11, CI 95% (−0.18, −0.03), Z = −2.82, p < 0.01. Trait anxiety has an increasing effect on the intensity of the negative impact of the COVID-19 pandemic, 0.23, CI 95% (.10, 0.35), Z = 3.56, p < 0.01, and the negative impact of the COVID-19 pandemic has a decreasing effect on quality of life, −0.47, CI 95% (−0.67, −0.27), Z = −4.62, p < 0.01. Gender and age did not moderate the relationship between the negative impact of COVID-19 and athletes’ quality of life. The results of the study highlighted the impact that social isolation and quarantine have on athletes’ affective well-being.


2021 ◽  
pp. 136749352110129
Author(s):  
Alice S Schamong ◽  
Hannah Liebermann-Jordanidis ◽  
Konrad Brockmeier ◽  
Elisabeth Sticker ◽  
Elke Kalbe

Congenital heart disease (CHD) is a major global health problem. Until recently, the siblings of this group did not receive much attention. This review, conducted from November 2019 to October 2020, aims to summarize knowledge about psychosocial well-being and quality of life (QoL), associated factors, and interventions for siblings of children with CHD. Systematic searches were conducted in PubMed, PsycINFO, PsycARTICLES, Web of Science via EBSCOhost, and CENTRAL. Twelve articles were included. Results showed that psychosocial well-being was impaired in 14% to 40% of siblings. Negative impact of illness was highest for CHD siblings compared to siblings of children with cancer, cystic fibrosis, or diabetes. QoL was impaired in up to one-third. Siblings of children with CHD and cancer rated their QoL lower than those of siblings of children with cystic fibrosis or type-1 diabetes. Associated factors were sibling age, gender, socioeconomic status, miscarriage, previous sibling death, visibility of illness, and severity of condition. Only one of two interventions focused on siblings of CHD children. Although data are scarce and inhomogeneous, it indicates that siblings of CHD children suffer from lower psychosocial well-being and QoL than siblings of children with other chronic conditions. Interventions to improve their situation should be developed.


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