scholarly journals Three-Component One-Pot Synthesis of Novel Benzo[b]1,8-naphthyridines Catalyzed by Bismuth(III) Chloride

2008 ◽  
Vol 2008 ◽  
pp. 1-4
Author(s):  
Tangali R. Ravikumar Naik ◽  
Halehatty S. Bhojya Naik ◽  
Halehatty R. Prakasha Naik ◽  
P. J. Bindu
Keyword(s):  
Room Temperature ◽  
Environmentally Friendly ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
One Pot Synthesis ◽  
High Yields

A novel and efficient three-component one-pot synthesis of benzo[b]1,8-naphthyridines by 2-amino-4-methylquinoline, aromatic aldehydes, and malononitrile was done. The reaction was catalyzed by an acidic Bismuth(III) chloride, functionalized Bismuth(III) chloride, at room temperature to give various benzo[b]1,8-naphthyridines in high yields. The Bismuth(III) chloride is an environmentally friendly catalyst.

scholarly journals A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction

2012 ◽  
Vol 9 (4) ◽  
pp. 2239-2244 ◽  
Author(s):  
Hossein Anaraki-Ardakani ◽  
Maziar Noei ◽  
Mina Karbalaei-Harofteh ◽  
Shahab Zomorodbakhsh
Keyword(s):  
Room Temperature ◽  
Facile Synthesis ◽  
One Pot ◽  
Pyrrole Derivatives ◽  
Dialkyl Acetylenedicarboxylates ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields ◽  
Neutral Conditions

A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.

Efficient One-Pot Synthesis of 12-Aryl-8,9,10,12-Tetrahydrobenzo[a]Xanthen-11-one Derivatives Using NaHSO4 as Catalyst in Ionic Liquid

2010 ◽  
Vol 113-116 ◽  
pp. 1993-1996 ◽  
Author(s):  
Hong Jun Zang ◽  
Yong Zhang ◽  
Bo Wen Cheng
Keyword(s):  
Ionic Liquid ◽  
Reaction Time ◽  
Environmentally Friendly ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
Short Reaction Time ◽  
One Pot Synthesis ◽  
Three Component Coupling

A series of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one derivatives were synthesized via the three-component coupling from aromatic aldehydes, 2-naphthol and 5,5–dimethylcyclohexane -1,3-dione catalyzed by NaHSO4 in ionic liquid, 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM]BF4). The reaction proceeded with good yields under short reaction time. The NaHSO4 was not expensive and the ionic liquid could be reused. The proposed method is efficient and environmentally friendly.

scholarly journals Microwave-assisted efficient one-pot synthesis of N 2-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines

2020 ◽  
Vol 16 ◽  
pp. 1706-1712
Author(s):  
Moustafa Sherief Moustafa ◽  
Ramadan Ahmed Mekheimer ◽  
Saleh Mohammed Al-Mousawi ◽  
Mohamed Abd-Elmonem ◽  
Hesham El-Zorba ◽  
...  
Keyword(s):  
Microwave Heating ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
X Ray ◽  
X Ray Crystallography ◽  
Microwave Assisted ◽  
One Pot Synthesis ◽  
High Yields

An efficient one-pot synthesis of N 2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of the obtained products.

An Efficient and Simple One-Pot Synthesis of ?-Acetamido Ketones Catalyzed by Ytterbium Triflate in Ionic Liquid

2009 ◽  
Vol 62 (4) ◽  
pp. 322 ◽  
Author(s):  
Anil Kumar ◽  
M. Sudershan Rao ◽  
Israr Ahmad ◽  
Bharti Khungar
Keyword(s):  
Ionic Liquid ◽  
Room Temperature ◽  
Acetyl Chloride ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
One Pot Synthesis ◽  
Ytterbium Triflate ◽  
Three Component Coupling

Ytterbium triflate immobilized in the ionic liquid [bmim][BF4] catalyzes the three-component coupling of aromatic aldehydes, enolizable ketones, and acetonitrile in the presence of acetyl chloride at room temperature to afford β-acetamido ketones in good yields. The catalyst can be recovered and recycled for subsequent reactions without any appreciable loss of efficiency.

Eco-Friendly Synthesis of 2-Substituted Benzimidazoles Using Air as the Oxidant

2013 ◽  
Vol 66 (2) ◽  
pp. 262 ◽  
Author(s):  
Guo-Feng Chen ◽  
Hai-Dong Shen ◽  
Hui-Ming Jia ◽  
Li-Yan Zhang ◽  
Hong-Yan Kang ◽  
...  
Keyword(s):  
Room Temperature ◽  
Environmentally Friendly ◽  
Aromatic Aldehydes ◽  
Absolute Ethanol ◽  
One Pot ◽  
Mild Conditions ◽  
One Pot Condensation ◽  
The One

A simple, environmentally friendly procedure for the synthesis of 2-substituted benzimidazoles by the one-pot condensation of o-phenylenediamines with aromatic aldehydes using continuous bubbling of air in absolute ethanol at room temperature is described. The simplicity of the system, mild conditions, involvement of a non-toxic and practically inexhaustible oxidant, easy and quick isolation of the products, and moderate to good yields are the main advantages of this procedure.

scholarly journals An efficient green synthesis of novel 1H-imidazo[1,2-a]imidazole-3-amine and imidazo[2,1-c][1,2,4]triazole-5-amine derivatives via Strecker reaction under controlled microwave heating

2019 ◽  
Vol 8 (1) ◽  
pp. 297-301 ◽  
Author(s):  
Kamal Usef Sadek ◽  
Afaf Mohamed Abdel-Hameed ◽  
Hisham A. Abdelnabi ◽  
Yasser Meleigy
Keyword(s):  
Reaction Time ◽  
Green Synthesis ◽  
Microwave Heating ◽  
Environmentally Friendly ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
Short Reaction Time ◽  
Strecker Reaction ◽  
Benzoyl Cyanide ◽  
High Yields

Abstract A highly efficient multi-component one-pot synthesis of novel 1H-imidazo[1,2-a]imidazole-3-amine and imidazo[2,1-c][1,2,4]triazole-5-amine derivatives has been developed through the reaction of easily available aromatic aldehydes, benzoyl cyanide and either 2-aminoimidazole-4,5-dicarbonitrile or 3-amino-1,2,4-triazole in pyridine under controlled microwave heating. The process is environmentally friendly, is operationally simple, with short reaction time and with high yields.

scholarly journals Environmental-friendly one-pot cascade synthesis of 3-cyanopiperidin-2,6-diones

2019 ◽  
Vol 18 (1) ◽  
pp. 165-170 ◽  
Author(s):  
Daniel Paprocki ◽  
Stanisław Berłożecki ◽  
Ryszard Ostaszewski
Keyword(s):  
Natural Products ◽  
Silica Gel ◽  
Knoevenagel Condensation ◽  
Environmentally Friendly ◽  
Aromatic Aldehydes ◽  
Cyanoacetic Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Environmental Friendly ◽  
Wide Range

Abstract 3-Cyanopiperidin-2,6-diones are key intermediates in the synthesis of several drugs and natural products. We developed  one-pot synthesis of 3-cyanopiperidin-2,6-diones by Knoevenagel condensation of cyanoacetic acid and aldehydes, followed by addition of cyanoacetic acid, Achmatowicz reaction and decarboxylation. We tested a wide range of aliphatic and aromatic aldehydes. Products were obtained under simple, environmentally friendly conditions and in yields up to 99%. Substrates were stirred in toluene at reflux, and filtered through short pad of silica gel, and the product was purified by recrystallization.

scholarly journals Microwave-assisted efficient one-pot synthesis of N 2-(tetrazol-5-yl)-6-aryl/heteroaryl-2,3-dihydro-1,3,5-triazine-2,4-diamines

2020 ◽  
Author(s):  
Moustafa Moustafa ◽  
Ramadan Mekheimer ◽  
Saleh Al-Mousawi ◽  
Mohamed Abd-Elmonem ◽  
Hesham El-Zorba ◽  
...  
Keyword(s):  
Microwave Heating ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
X Ray ◽  
X Ray Crystallography ◽  
Microwave Assisted ◽  
One Pot Synthesis ◽  
High Yields

An efficient one-pot synthesis of N 2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of obtained products.  

scholarly journals A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines

SynOpen ◽  
2018 ◽  
Vol 02 (02) ◽  
pp. 0207-0212 ◽  
Author(s):  
Feize Liu ◽  
Xueling Hou ◽  
Li Nie ◽  
Khurshed Bozorov ◽  
Michael Decker ◽  
...  
Keyword(s):  
Aromatic Aldehydes ◽  
One Pot ◽  
One Pot Synthesis ◽  
Convenient Synthesis ◽  
Three Component Reaction ◽  
Simple Protocol ◽  
High Yields

An efficient, simple protocol has been established for convenient synthesis of novel 2,3-disubstituted thieno[2,3-d]pyrimidin-4(3H)-one derivatives in good to high yields through a one-pot, two-step and three-component reaction from 2H-thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, aromatic aldehydes, and amines.

Sign in / Sign up

Export Citation Format

Share Document