scholarly journals Isolation, Synthesis and Characterization of Rosiglitazone Maleate Impurities

2008 ◽  
Vol 5 (3) ◽  
pp. 562-566
Author(s):  
Singamsetty Radha Krishna ◽  
Mandava Venkata Naga Brahmeshwar Rao ◽  
Tirmalaraju Satyanaryana Raju ◽  
Vurimidi Himabindu ◽  
Ghanta Mahesh Reddy
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Mass Number ◽  
Synthesis And Characterization ◽  
Reverse Phase ◽  
Bulk Drug

Three unknown impurities in rosiglitazone maleate 1 bulk drug at level below 0.1% (ranging from 0.05 to 0.1%) were detected by simple reverse phase high performance liquid chromatography. These impurities were preliminarily identified with LC-MS and characterized by the mass number of the impurities. Different experiments were conducted and finally synthesized and characterized the unknown impurities.

scholarly journals Synthesis, Isolation and Characterization of Process-Related Impurities in Oseltamivir Phosphate

2012 ◽  
Vol 9 (1) ◽  
pp. 113-120 ◽  
Author(s):  
Yogesh Kumar Sharma ◽  
Dau Dayal Agarwal ◽  
Sudesh Bhure ◽  
Sanjay Singh Rathore ◽  
Chakravir Rawat ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Mass Number ◽  
Reverse Phase ◽  
Related Impurities ◽  
Isolation And Characterization ◽  
Bulk Drug ◽  
Oseltamivir Phosphate

Three known impurities in oseltamivir phosphate bulk drug at level 0.1% (ranging from 0.05-0.1%) were detected by gradient reverse phase high performance liquid chromatography. These impurities were preliminarily identified by the mass number of the impurities. Different experiments were conducted and finally the known impurities were synthesized and characterized.

scholarly journals Synthesis, Isolation and Characterization of Process-Related Impurities in Salbutamol Sulphate

2011 ◽  
Vol 8 (4) ◽  
pp. 1720-1727 ◽  
Author(s):  
Yogesh Kumar Sharma ◽  
Dau Dayal Agarwal ◽  
Sudesh Bhure ◽  
Rajendra Nath Mukharjee ◽  
Pramod Kumar Sahu ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Mass Number ◽  
Reverse Phase ◽  
Salbutamol Sulphate ◽  
Related Impurities ◽  
Isolation And Characterization ◽  
Bulk Drug

Three known and one unknown impurities in salbutamol sulphate bulk drug at level 0.1% (ranging from 0.05-0.1%) were detected by gradient reverse phase high performance liquid chromatography. These impurities were preliminarily identified by the mass number of the impurities. Different experiments were conducted and finally synthesized and characterized the known and unknown imputities.

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