scholarly journals Pancreatic Neuroendocrine Tumours: Established Role of Endoscopic Ultrasound in High-Risk Populations

2008 ◽  
Vol 22 (10) ◽  
pp. 809-809
Author(s):  
Eric C Lam
Keyword(s):  
High Risk ◽  
Endoscopic Ultrasound ◽  
Neuroendocrine Tumours ◽  
High Risk Populations ◽  
Pancreatic Neuroendocrine Tumours ◽  
Established Role

The role of endoscopic ultrasound in diagnosing pancreatic neuroendocrine tumours

Oncoreview ◽  
2018 ◽  
Vol 8 (1) ◽  
pp. 19-23
Author(s):  
Przemysław Dyrla ◽  
Magdalena Chmielewska ◽  
Marta Mazur ◽  
Przemysław Witek
Keyword(s):  
Endoscopic Ultrasound ◽  
Neuroendocrine Tumours ◽  
Pancreatic Neuroendocrine Tumours

Pancreatic Neuroendocrine Tumours: The Role of Endoscopic Ultrasound Biopsy in Diagnosis and Grading Based on the WHO 2017 Classification

2019 ◽  
Vol 37 (4) ◽  
pp. 325-333 ◽  
Author(s):  
Milena Di Leo ◽  
Laura Poliani ◽  
Daoud Rahal ◽  
Francesco Auriemma ◽  
Andrea Anderloni ◽  
...  
Keyword(s):  
Endoscopic Ultrasound ◽  
Neuroendocrine Tumours ◽  
Histological Grade ◽  
Accurate Method ◽  
Biopsy Material ◽  
Ki 67 ◽  
Surgical Specimen ◽  
Study Population ◽  
Pancreatic Neuroendocrine Tumours

Background: One of the controversial issues in the diagnosis of pancreatic neuroendocrine tumours (pNETs) is the accurate prediction of their clinical behaviour. Objectives: The aim of the study was to evaluate the role of endoscopic ultrasound (EUS) biopsy in the diagnosis and grading of pNETs in a certified ENETS Center. Methods: A prospectively maintained database of EUS biopsy procedures was retrospectively reviewed to identify all consecutive patients referred to a certified ENETS Center with a suspicion of pNET between June 2014 and April 2017. The cytological and/or histological specimens were stained and the Ki-67 labeling index was evaluated. In patients undergoing surgery, the grade obtained with EUS-guided biopsy was compared with the final histological grade. The grade was evaluated according to the 2017 WHO classifications and grading. Results: The study population included 59 patients. EUS biopsy material reached an adequacy of 98.3% and was adequate for Ki-67 evaluation in 84.7% of cases. Twenty-nine patients (49.2%) underwent surgery. Of these, 25 patients had Ki-67 evaluated on EUS biopsy: the agreement between EUS biopsy grading and surgical specimen grading was 84%. Conclusion: EUS biopsy is an accurate method for the diagnosis and grading of pNETs based on the WHO 2017 Ki-67 labelling scheme.

Imaging of Pancreatic-Neuroendocrine Tumours: An Outline of Conventional Radiological Techniques

2019 ◽  
Vol 12 (2) ◽  
pp. 135-155 ◽  
Author(s):  
Muhammad Affan Zamir ◽  
Wasim Hakim ◽  
Siraj Yusuf ◽  
Robert Thomas
Keyword(s):  
Neuroendocrine Tumours ◽  
Treatment Options ◽  
Advantages And Disadvantages ◽  
Imaging Characteristics ◽  
Fundamental Understanding ◽  
Pancreatic Neuroendocrine Tumours ◽  
Direct Management ◽  
Important Disease ◽  
Similar Imaging

IIntroduction: Pancreatic Neuroendocrine Tumours (p-NETs) are an important disease entity and comprise of peptide-secreting tumours often with a functional syndrome. : Accounting for a small percentage of all pancreatic tumours, they have a good overall survival rate when diagnosed early, with surgery being curative. The role of nuclear medicine in the diagnosis and treatment of these tumours is evident. However, the vast majority of patients will require extensive imaging in the form of conventional radiological techniques. It is important for clinicians to have a fundamental understanding of the p-NET appearances to aid prompt identification and to help direct management through neoplastic staging. Methods: This article will review the advantages and disadvantages of conventional radiological techniques in the context of p-NETs and highlight features that these tumours exhibit. Conclusion: Pancreatic neuroendocrine tumours are a unique collection of neoplasms that have markedly disparate clinical features but similar imaging characteristics. Most p-NETs are small and welldefined with homogenous enhancement following contrast administration, although larger and less welldifferentiated tumours can demonstrate areas of necrosis and cystic architecture with heterogeneous enhancement characteristics. : Prognosis is generally favourable for these tumours with various treatment options available. However, conventional radiological techniques will remain the foundation for the initial diagnosis and staging of these tumours, and a grasp of these modalities is extremely important for physicians.

Role of 68Ga-DOTATOC PET-CT in the diagnosis and staging of pancreatic neuroendocrine tumours

2011 ◽  
Vol 21 (11) ◽  
pp. 2408-2416 ◽  
Author(s):  
Rakesh Kumar ◽  
Punit Sharma ◽  
Pramod Garg ◽  
Sellam Karunanithi ◽  
Niraj Naswa ◽  
...  
Keyword(s):  
Neuroendocrine Tumours ◽  
Pet Ct ◽  
Pancreatic Neuroendocrine Tumours

Current Status of Breast Ultrasound

2011 ◽  
Vol 62 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Anat Kornecki
Keyword(s):  
High Risk ◽  
Breast Imaging ◽  
Breast Ultrasound ◽  
Current Status ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Tumour Extension ◽  
The Status ◽  
High Risk Populations

Ultrasound (US) has a significant role in diagnostic breast imaging. It is most commonly used as an adjunctive test in characterizing lesions detected by other imaging modalities or by clinical examination. US is recognized as the modality of choice in the evaluation of women who are symptomatic and younger than 30 years of age, pregnant, or lactating. Combined mammography and US appear to have a role in screening high-risk populations. The use of standard Breast Imaging Reporting and Data System US lexicon is helpful in guiding the differentiation between benign and malignant sonographic signs. Biopsy is warranted when benign features are absent or for any feature consistent with malignancy, despite other benign findings. Whole breast and axillary US are useful in assessing tumour extension, multifocality, and the status of axillary lymph nodes. US is the modality of choice for guiding interventional breast procedures. The role of US as a guidance tool for nonoperative breast treatment is being investigated.

Delivering Prevention: The Role of Public Programs in Delivering Care to High-Risk Populations

Medical Care ◽  
1999 ◽  
Vol 37 (SUPPLEMENT) ◽  
pp. JS264-JS278 ◽  
Author(s):  
Leslie L. Roos ◽  
Dawn Traverse ◽  
Donna Turner
Keyword(s):  
High Risk ◽  
Public Programs ◽  
High Risk Populations

scholarly journals The Historical Role of the Plastic Surgeon in Spine Reconstruction

2021 ◽  
Vol 35 (01) ◽  
pp. 003-009
Author(s):  
Annie Do ◽  
Matthew J. Davis ◽  
Amjed Abu-Ghname ◽  
Sebastian J. Winocour ◽  
Edward M. Reece ◽  
...  
Keyword(s):  
High Risk ◽  
Spine Surgery ◽  
Plastic Surgeon ◽  
Wound Complications ◽  
Muscle Flaps ◽  
Postoperative Wound ◽  
High Risk Populations ◽  
Historical Role ◽  
Posterior Trunk

AbstractWound complications occur in up to 19% of patients undergoing complex spine surgery. The role of the plastic surgeon in complex and redo spine surgery is important and evolving. Classically, plastic surgeons have been involved in the management of patients who develop wound complications following surgery. This involves reconstruction of posterior trunk defects with locoregional fasciocutaneous, muscle, and free tissue transfers. There has also been an increasing role for plastic surgeons to become involved in prophylactic closures of complex and/or redo spine surgeries for high-risk populations. Identification of patients with comorbidities and likelihood for multiple reoperations who are prophylactically treated with complex closure with or without local muscle flaps could significantly decrease the postoperative wound complications.

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