scholarly journals Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma

2007 ◽  
Vol 2007 ◽  
pp. 1-3 ◽  
Author(s):  
A. Işın Doğan-Ekici ◽  
Alp Usubütün ◽  
Türkan Küçükali ◽  
Ali Ayhan
Keyword(s):  
Endometrial Carcinoma ◽  
Genital Tract ◽  
Plasma Cells ◽  
Histopathological Examination ◽  
Female Genital Tract ◽  
Giant Cells ◽  
Polymorphonuclear Leucocytes ◽  
Xanthogranulomatous Inflammation ◽  
Post Menopausal ◽  
Female Genital

Xanthogranulomatous inflammation is a distinguished histopathological entity affecting several organs, predominantly the kidney and gallbladder. So far, only a small number of cases of xanthogranulomatous inflammation occurring in female genital tract have been described, most frequently affecting the endometrium and histologically characterized by replacement of endometrium by xanthogranulomatous inflammation composed of abundant foamy histiocytes, siderophages, giant cells, fibrosis, calcification and accompanying polymorphonuclear leucocytes, plasma cells and lymphocytes of polyclonal origin. We present a case of a 69-year-old female complained of post menopausal bleeding and weight loss. Clinical preliminary diagnoses were endometrial carcinoma or hyperplasia and ultrasound was supposed to be endometrial malignancy, hyperplasia or pyometra by radiologist. Histopathological examination of uterus revealed xanthogranulomatous endometritis. Since xanthogranulomatous endometritis may mimic endometrial malignancy clinically and pathologically as a result of the replacement of the endometrium and occasionally invasion of the myometrium by friable yellowish tissue composed of histiocytes, knowledge of this unusual inflammatory disease is needed for both clinicians and pathologists.

scholarly journals Controversies in the Management of Endometrial Carcinoma: An Update

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Mohamed K. Mehasseb ◽  
John A. Latimer
Keyword(s):  
Radiation Therapy ◽  
Endometrial Cancer ◽  
Early Detection ◽  
Endometrial Carcinoma ◽  
Genital Tract ◽  
Female Genital Tract ◽  
Developed Countries ◽  
Changing Roles ◽  
The Developed Countries ◽  
Female Genital

Endometrial carcinoma is the commonest type of female genital tract malignancy in the developed countries. Endometrial carcinoma is usually confined to the uterus at the time of diagnosis and as such usually carries an excellent prognosis with high curability. Our understanding and management of endometrial cancer have continuously developed. Current controversies focus on screening and early detection, the extent of nodal surgery, and the changing roles of radiation therapy and chemotherapy and will be discussed in this paper.

scholarly journals Spectrum of histopathological lesions in the fallopian tubes

2013 ◽  
Vol 3 (5) ◽  
pp. 356-360 ◽  
Author(s):  
S Gon ◽  
A Basu ◽  
B Majumdar ◽  
TK Das ◽  
M Sengupta ◽  
...  
Keyword(s):  
Genital Tract ◽  
Histopathological Examination ◽  
Female Genital Tract ◽  
Secondary Malignancies ◽  
Fallopian Tubes ◽  
Serial Sections ◽  
Pathology Laboratory ◽  
Surgical Specimen ◽  
Neoplastic Lesions ◽  
Female Genital

Background: Fallopian tubes are common surgical specimen in the pathology laboratory; still there is a lack of data to describe the frequency of various histological fi ndings. The aim and objectives of this study was to describe the various histopathological fi ndings of fallopian tubes. Materials and Methods: Two thousand fi ve hundred and seventy fi ve cases where fallopian tubes were removed either separately or along with other female genital tract organs were studied retrospectively and their histopathological fi ndings documented. Results: Ectopic pregnancy comprised maximum number of cases closely followed by salpingitis. Primary neoplastic lesions were rare as compared to secondary malignancies. Serial sections of fallopian tube and sections from representative areas are essential for a pathologist so that the diagnosis of these pathological entities is not missed. Conclusion: Though the fallopian tubes remain unremarkable in majority of the surgical pathological specimens, it must be subjected for histopathological examination to demonstrate the pathological lesions. Journal of Pathology of Nepal (2013) Vol. 3, No.1, Issue 5, 356-360 DOI: http://dx.doi.org/10.3126/jpn.v3i5.7858

Atypical xanthogranulomatous inflammation of the female genital tract

2018 ◽  
Vol 222 ◽  
pp. 186-187
Author(s):  
Sunil Jaiman ◽  
Sirisha R. Gundabattula ◽  
Shashikala Dasari ◽  
Manjula Pochiraju
Keyword(s):  
Genital Tract ◽  
Female Genital Tract ◽  
Xanthogranulomatous Inflammation ◽  
Female Genital

scholarly journals Xanthogranulomatous Inflammation of the Female Genital Tract: Report of Three Cases

2012 ◽  
Vol 3 ◽  
pp. 100-106 ◽  
Author(s):  
Xiang-sheng Zhang ◽  
Hong-yan Dong ◽  
Lei-lei Zhang ◽  
Mohamed Mokhtar Desouki ◽  
Chengquan Zhao
Keyword(s):  
Genital Tract ◽  
Female Genital Tract ◽  
Xanthogranulomatous Inflammation ◽  
Female Genital

scholarly journals Hydatid cyst of broad ligament: a rare case report

2020 ◽  
Vol 7 (4) ◽  
pp. 1298
Author(s):  
Ajay Gujar ◽  
Jayant Pednekar ◽  
Nida Khan ◽  
Anurag Tiwary ◽  
Rohith Pillai ◽  
...  
Keyword(s):  
Hydatid Cyst ◽  
Genital Tract ◽  
Histopathological Examination ◽  
Broad Ligament ◽  
Female Genital Tract ◽  
Surgical Excision ◽  
Cystic Mass ◽  
Rare Case Report ◽  
Peculiar Case ◽  
Female Genital

Hydatid cyst is a parasitic disease caused by tapeworm Echinococcus. It affects the liver and lung most commonly, but may rarely affect fallopian tube, broad ligament and other structures. One such peculiar case is where a 17 years old female presented with a rapidly growing cystic mass in lower abdomen, clinically suspicious of ovarian mass or mesentric cyst. Investigations failed to identify the nature. On laparotomy, excision of the mass was done. Suprisingly histopathological examination identified the lesion as hydatid cyst arising from the broad ligament. Patient responded well to surgical excision followed by albendazole administration. Female genital tract hydatidosis is a rare entity and in most cases the involvement is secondary. Primary hydatid disease of female genital tract is even very rarer and generates considerable diagnostic difficulty.

scholarly journals Ovarian enterobiasis: a case report

2018 ◽  
Vol 6 (3) ◽  
pp. 1055 ◽  
Author(s):  
Geethu G. Nair ◽  
Prejisha Balan
Keyword(s):  
Gastrointestinal Tract ◽  
Cross Section ◽  
Genital Tract ◽  
Histopathological Examination ◽  
Incidental Finding ◽  
Female Genital Tract ◽  
Inflammatory Cells ◽  
Enterobius Vermicularis ◽  
Intestinal Nematode ◽  
Female Genital

Enterobius vermicularis (the pinworm) is the most common intestinal nematode in gastrointestinal tract of humans. It commonly infests the lumen of the intestine but on rare occasions has been found in the wall or in the tissues outside the gastrointestinal tract; female genital tract and peritoneum being the commonest sites. It is usually seen as an incidental finding. This is a case of 29-year-old female presented for elective sterilization. A tiny nodule was noted on the surface of ovary during procedure which was sent for histopathological examination. Lesion was composed of necrotic areas and inflammatory cells with cross section of a degenerated worm. The features of the eggs were diagnostic of Enterobius vermicularis. Multiple histologic sections may be required to establish diagnosis in older lesions as in this case.

scholarly journals Cervical superficial myofibroblastoma: Case report and review of the literature

2017 ◽  
Vol 5 ◽  
pp. 2050313X1772693
Author(s):  
Mohamed Abdelaziz ◽  
Noura Eziba ◽  
Suash Sharma ◽  
Daniel Kleven ◽  
Ayman Al-Hendy
Keyword(s):  
Genital Tract ◽  
Histopathological Examination ◽  
Smooth Muscle Actin ◽  
Female Genital Tract ◽  
Uterine Fibroids ◽  
Review Of The Literature ◽  
Cervical Mass ◽  
Submucosal Mass ◽  
Mass Lesions ◽  
Female Genital

Superficial myofibroblastoma of the lower female genital tract is a rare benign, recently recognized neoplasm that mostly affects the vulvovaginal area. Our report discusses a case of cervical superficial myofibroblastoma of the lower female genital tract in a 45-year-old patient who is presented with menometrorrhagia. On examination, she had multiple uterine fibroids and a circumscribed submucosal mass lesion involving the anterior lip of cervix. At hysterectomy, histopathological examination of the cervical mass revealed a relatively hypocellular tumor consisted of bland spindled and stellate cells. An immunohistochemistry evaluation revealed reactivity for CD34, desmin, and smooth muscle actin. This neoplasm should be included in the differential diagnosis of cervical mass lesions. This tumor also needs to be differentiated from other mesenchymal lesions of lower female genital tract.

scholarly journals Cervical Angiomyolipoma Coexisting with Endometrial Carcinoma in the Absence of Tuberous Sclerosis: A Rare Case Report

2021 ◽  
Vol 42 (03) ◽  
pp. 305-308
Author(s):  
Femela Muniraj ◽  
C Divyapriya ◽  
Vijayashree Raghavan ◽  
Rajesh Kanna Nandhagopal Radha ◽  
Sailatha Ramanujam ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Smooth Muscle ◽  
Endometrial Carcinoma ◽  
Tuberous Sclerosis ◽  
Blood Vessels ◽  
Genital Tract ◽  
Female Genital Tract ◽  
World Health ◽  
Hmb 45 ◽  
Female Genital

AbstractAngiomyolipoma (AML) is a rare benign mesenchymal neoplasm composed of variable admixture of blood vessels, smooth muscle, and adipose tissue; most commonly located in kidney, and is usually associated with tuberous sclerosis. Extrarenal AML has been reported in various sites, although infrequently in female genital tract (FGT). AML in cervix is extremely rare and only six cases have been reported so far. A 46-year-old postmenopausal female presented with lower abdominal pain, bleeding for 4 days and a polypoidal mass protruding through the cervical os. Endometrial curettings were suggestive of endometrial adenocarcinoma—endometrioid type (World Health Organization [WHO]). The subsequent hysterectomy specimen confirmed the diagnosis and the histologic grade was International Federation of Obstetrics and Gynecology (FIGO) grade I and stage was pT1aN0 (American Joint Committee on Cancer [AJCC], 8th edition). Cervical polyp showed AML. CD34 and smooth muscle actin (SMA) showed diffuse positivity in blood vessels and smooth muscle cells, respectively. HMB-45 was negative. This is the first ever reported case of AML coexisting with endometrial carcinoma in the absence of tuberous sclerosis. CD34 is a good marker for delineating the blood vessels and SMA for both the smooth muscle and vascular components. S100 is generally not needed to prove the adipose tissue component. HMB-45 is not consistently expressed in AML of female genital tract.

A Rare Case of Cavernous Angiomatosis of the Uterus

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S79-S79
Author(s):  
V Prakash ◽  
C E Middleton ◽  
V Shenoy
Keyword(s):  
Genital Tract ◽  
Histopathological Examination ◽  
English Literature ◽  
Female Genital Tract ◽  
Uterine Fibroids ◽  
Abnormal Uterine Bleeding ◽  
Accurate Diagnosis ◽  
Vascular Tumors ◽  
Unexpected Finding ◽  
Female Genital

Abstract Introduction/Objective Angiomatosis is a rare, non-neoplastic vascular malformation characterized by the proliferation of blood vessels which involve skin, soft tissue, and bone. Angiomatosis of the female genital tract is extremely rare with very few cases described in the English literature. Methods/Case Report We present a case of an unexpected finding of angiomatosis of the uterus and cervix in a 34- year-old nulliparous female with a history of abnormal uterine bleeding and dysmenorrhea of one year duration. Imaging studies showed an anteverted uterus measuring 9 cm × 6 cm × 5 cm with thickened irregular endometrium, blood clots within the endometrial cavity, and subserosal uterine fibroids. A subsequent endometrial curettage showed benign superficial endometrium. Hysterectomy was performed and histopathological examination revealed diffuse haphazardly arranged large vascular channels within the uterine wall and cervical stroma. A diagnosis of cavernous angiomatosis of the uterus and cervix was made. Results (if a Case Study enter NA) NA Conclusion Angiomatosis of the female genital tract is a rare vascular proliferation that tends to grow at a slow rate and cause heavy menstrual bleeding in otherwise healthy patients. Differential diagnoses of angiomatosis include other vascular tumors such as hemangiomas, lymphangioma, arteriovenous malformation and papillary endothelial hyperplasia. Clinical examination and investigations like hysteroscopy, endometrial curettage and ultrasonography may not help in accurate diagnosis. Definitive diagnosis relies heavily on histopathological examination. Treatment of symptomatic angiomatosis is purely surgical and in our case, was curative. Following treatment, recurrences can occur and appropriate surveillance is recommended. Malignant transformation have not been reported. It is important to be aware of this rare entity to make an accurate diagnosis.

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