scholarly journals Aspiration in the Context of Upper Gastrointestinal Endoscopy

2007 ◽  
Vol 21 (4) ◽  
pp. 223-225 ◽  
Author(s):  
A Thomson ◽  
J Tye-Din ◽  
S Tonga ◽  
J Scott ◽  
C Mclaren ◽  
...  
Keyword(s):  
Pilot Study ◽  
Gastrointestinal Endoscopy ◽  
Pulmonary Aspiration ◽  
Upper Gastrointestinal Endoscopy ◽  
Life Threatening ◽  
The Mean ◽  
Clinically Significant ◽  
Upper Gastrointestinal ◽  
Nuclear Scanning ◽  
Present Pilot Study

BACKGROUND: Pulmonary aspiration is a life-threatening complication of upper gastrointestinal endoscopy, the incidence of which has not been determined. Endoscopy-related aspiration has not been studied in procedures in which patients swallow a radiolabelled potential aspirate immediately before endoscopy and undergo nuclear scanning postprocedure.METHODS: A pilot study was conducted in which 200 MBq of non-absorbable technetium-99m phytate in 10 mL of water was administered orally to 50 patients who were about to undergo endoscopy. Gamma camera images were obtained to ensure that there had been no aspiration before endoscopy. After endoscopy, a repeat scan was performed. Fluid aspirated through the endoscope was also collected and analyzed for radioactivity using a hand-held radiation monitor.RESULTS: No evidence of pulmonary aspiration was found in any of the patients studied. The mean estimated percentage of the initially administered radioactivity aspirated through the endoscope was 2.66% (range 0% to 10.3%).CONCLUSION: The present pilot study confirms earlier observations that clinically significant aspiration in the context of upper gastrointestinal endoscopy is uncommon. The incidence of aspiration may, however, be different in acutely bleeding patients undergoing endoscopy. For logistic reasons, this group could not be studied.

scholarly journals Minimally invasive approach to esophageal lipoma

2020 ◽  
Vol 2020 (7) ◽  
Author(s):  
Daniele Bernardi ◽  
Davide Ferrari ◽  
Stefano Siboni ◽  
Matteo Porta ◽  
Barbara Bruni ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Gastrointestinal Endoscopy ◽  
Clinical Presentation ◽  
Upper Gastrointestinal Endoscopy ◽  
Minimally Invasive Approach ◽  
Invasive Approach ◽  
Life Saving ◽  
Recurrent Vomiting ◽  
Life Threatening ◽  
Upper Gastrointestinal

Abstract Esophageal lipoma is a rare neoplasm with heterogeneous and sometimes life-threatening clinical presentation. We report the case of two patients, a 77-year-old man and a 69-year-old woman presenting with heartburn and dysphagia, and with recurrent vomiting and asphyxia, respectively. Upper gastrointestinal endoscopy and computed tomography were highly suggestive of the diagnosis of esophageal lipoma and identified an intramural and an intraluminal pedunculated mass originating, respectively, from the distal and the cervical esophagus. The first patient was treated by laparoscopic transhiatal enucleation and the second by transoral endoscopic resection under general anesthesia. Both had an uneventful postoperative course and were discharged home on postoperative day 2. Minimally invasive excision of esophageal lipoma is feasible and effective. It may be life-saving in patients with pedunculated tumors who suffer from intermittent regurgitation of a bulky polypoid mass in the mouth causing asphyxia.

scholarly journals HELICOBACTER PYLORI INFECTION;

2012 ◽  
Vol 19 (02) ◽  
pp. 202-207
Author(s):  
NABIHA FAISAL ◽  
MUHAMMAD MANSOOR UL HAQ ◽  
HAFEEZULLAH SHAIKH ◽  
Pervez Ashraf ◽  
Jamila. H. Esmail
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Tertiary Care ◽  
Upper Gastrointestinal Endoscopy ◽  
National Hospital ◽  
Cross Sectional ◽  
Duration Of Symptoms ◽  
Data Source ◽  
The Mean ◽  
H Pylori ◽  
Upper Gastrointestinal

Objective: To determine the frequency of H. pylori infection in dyspeptic patients undergoing endoscopy at a tertiary care centerin Karachi. Data source: Patients undergoing endoscopy at Liaquat National Hospital, Karachi. Design of study: Cross sectional descriptivestudy. Setting: Department of Gastroenterology, Liaquat National Hospital, Karachi. Period: May 2008–October 2008. Material andmethods: All adult patients with symptoms of dyspepsia for more than 1 month duration were included. Patients with upper gastrointestinalbleed, anemia or weight loss were excluded. Upper gastrointestinal endoscopy was performed in all patients and biopsy specimens two eachfrom antrum and body and one from fundus were taken for histology. Results: A total of 123 dyspeptic patients were included in the study. 76(61.8%) patients were males and 47 (38.2%) were females. H pylori was detected in mucosa of 49 (39.8%) patients. The mean age of thepatients was 41.41 ± 13.15 Years (95%CI; 39.06 to 43.75). Rate of H.pylori infection was not found statistical significant with age, gender,duration of symptoms and BMI. Conclusions: The prevalence of H pylori infection in dyspeptic patients was lower than reported in previousstudies from other centers in Pakistan. Other environmental factors should be evaluated in every patient especially who is negative for H. pyloriin our setup.

scholarly journals Appropriateness of Indications of Upper Gastrointestinal Endoscopy and its Association With Positive Finding

2018 ◽  
Vol 56 (209) ◽  
pp. 504-509 ◽  
Author(s):  
Tanka Prasad Bohara ◽  
Uttam Laudari ◽  
Abishek Thapa ◽  
Shail Rupakheti ◽  
Mukund Raj Joshi
Keyword(s):  
Odds Ratio ◽  
Gastrointestinal Endoscopy ◽  
Upper Gastrointestinal Endoscopy ◽  
Positive Finding ◽  
Significant Finding ◽  
Cross Sectional ◽  
Abdominal Symptoms ◽  
Clinically Significant ◽  
Upper Abdominal ◽  
Upper Gastrointestinal

Introduction:  Upper Gastrointestinal Endoscopy(UGIE) is a frequently advised investigation for upper abdominal symptoms. Studies have questioned the appropriateness of indications for UGIE and have shown that inappropriate indications range from 5% to 49%. The unnecessary UGIE expose patients to the risk. The number of UGIE is rising in our region and we assume so is the number of unnecessary UGIE. With an aim to evaluate the appropriateness of the indications of UGIE and compare its association with positive findings, we conducted a cross-sectional descriptive study. Methods: All patients undergoing diagnostic UGIE during the study period were included in the study. Appropriateness of indications for UGIE was defined as per American Society for Gastrointestinal Endoscopy(ASGE) criteria as “appropriate” and “inappropriate”. UGIE endoscopy findings were classified as “significant” and “insignificant” based on endoscopy findings. The extent of this association between the appropriateness of indications and UGIE findings was expressed as the odds ratio (OR) of finding a relevant diagnosis in patients with an ‘‘appropriate’’ indication compared with those with an ‘inappropriate’’ indication. Results: Seventy-nine patients were included in the study. Fifty- two (65.8 %) of the indications were considered appropriate as per ASGE guidelines. Thirty-three (63.5%) of the appropriate indications has clinically significant finding as compared to seven (25.9%) of inappropriate indication with an odds ratio of 4.962 (95%CI:1.773 – 13.890, p=0.002) which is statistically significant. Conclusions:  Appropriate indications have significantly higher rates of clinically significant findings. Use of guidelines may decrease the number of unnecessary procedures.

scholarly journals Drug-Induced Esophageal Ulcer in Adolescent Population: Experience at a Single Medical Center in Central Taiwan

Medicina ◽  
2021 ◽  
Vol 57 (12) ◽  
pp. 1286
Author(s):  
Shu-Wei Hu ◽  
An-Chyi Chen ◽  
Shu-Fen Wu
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Pediatric Patients ◽  
Upper Gastrointestinal Endoscopy ◽  
Esophageal Ulcer ◽  
Drug Induced ◽  
Inflammatory Drugs ◽  
The Mean ◽  
Anti Inflammatory ◽  
Upper Gastrointestinal ◽  
Esophageal Ulcers

Background and Objectives: Drug-induced esophageal ulcer is caused by focal drug stimulation. It may occur in adults and children. Limited research is available in pediatric patients with drug-induced esophageal ulcer; therefore, we designed this study to determine the characteristics of this disease in this population. Materials and Methods: Thirty-two pediatric patients diagnosed with drug-induced esophageal ulcers from a hospital database of upper gastrointestinal tract endoscopies were included. After treatment, patients were followed for 2 months after upper gastrointestinal endoscopy. Results: Female patients were predominant (56.2%/43.8%). The mean age of patients was 15.6 years (median, 16 years; interquartile range, 2 years). Doxycycline was administered in most cases (56.3%); other drugs were dicloxacillin, amoxicillin, clindamycin, L-arginine, and nonsteroidal anti-inflammatory drugs. Doxycycline was associated with kissing ulcers. Esophageal ulcers induced by nonsteroidal anti-inflammatory drugs were more often associated with gastric or duodenal ulcers. The most common location was the middle-third of the esophagus (78.1%). Patients were treated with proton pump inhibitors, sucralfate, or H2-blockers. The mean duration for which symptoms lasted was 9.2 days. No esophageal stricture was found in 24 patients who were followed for 2 months after upper gastrointestinal endoscopy. Conclusions: The authors suggest informing patients to take medicine with enough water (approximately 100 mL) and enough time (15–30 min) before recumbency, especially high-risk drugs, such as doxycycline or nonsteroidal anti-inflammatory drugs.

scholarly journals Novel mainstream capnometer system is safe and feasible even under CO2 insufflation during ERCP-related procedure: a pilot study

2019 ◽  
Vol 6 (1) ◽  
pp. e000266 ◽  
Author(s):  
Yoichi Takimoto ◽  
Eisuke Iwasaki ◽  
Tatsuhiro Masaoka ◽  
Seiichiro Fukuhara ◽  
Shintaro Kawasaki ◽  
...  
Keyword(s):  
Adverse Event ◽  
Pilot Study ◽  
Gastrointestinal Endoscopy ◽  
Conscious Sedation ◽  
Upper Gastrointestinal Endoscopy ◽  
Intravenous Sedation ◽  
Endoscopic Retrograde ◽  
Bite Block ◽  
End Tidal ◽  
Upper Gastrointestinal

Background and aimsThere is a need to safely achieve conscious sedation during endoscopic retrograde cholangiopancreatography (ERCP). We evaluated the safety and feasibility of a mainstream capnometer system to monitor apnoea during ERCP under CO2 insufflation.MethodsNon-intubated adult patients undergoing ERCP-related procedures with intravenous sedation were enrolled. End-tidal CO2 (EtCO2) was continuously monitored during the procedure under CO2 insufflation using a mainstream capnometer system, comprising a capnometer and a specially designed bite block for upper gastrointestinal endoscopy and ERCP. Oxygen saturation (SpO2) was also monitored continuously during the procedure. In this study, we evaluated the safety and feasibility of the capnometer system.ResultsEleven patients were enrolled. Measurement of EtCO2 concentration was possible from the beginning to the end of the procedure in all 11 cases. There was no measurement failure, dislocation of the bite block, or adverse event related to the bite block. Apnoea linked to hypoxaemia occurred five times (mean duration, 174.4 s).ConclusionThis study confirmed that apnoea was detected earlier than when using a percutaneous oxygen monitor. Measurement of EtCO2 concentration using the newly developed mainstream capnometer system was feasible and safe even under CO2 insufflation.

scholarly journals Pre-Endoscopy Drink of Simethicone and N-Acetylcysteine Significantly Improves Visualization in Upper Gastrointestinal Endoscopy

2021 ◽  
Vol 12 (01) ◽  
pp. 011-018
Author(s):  
Shrihari Anil Anikhindi ◽  
Ashish Kumar ◽  
Noriya Uedo ◽  
Vikas Singla ◽  
Akshay Anikhindi ◽  
...  
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Duodenal Bulb ◽  
Gastric Fundus ◽  
Gastric Body ◽  
Upper Gastrointestinal Endoscopy ◽  
Optimal Outcomes ◽  
The Mean ◽  
The Difference ◽  
Upper Gastrointestinal ◽  
Control Study

Abstract Introduction With the advancements in diagnostic and therapeutic upper gastrointestinal endoscopy (UGIE), clear mucosal visualization is essential to ensure optimal outcomes. Though routinely followed in Japan and Korea, pre-endoscopic preparation is seldom used in India. We evaluated the efficacy of a pre-endoscopic drink of N-acetylcysteine (NAC) and simethicone in improving mucosal visibility during UGIE. Patients and Methods This study was a retrospective, investigator blind study with a case–control study design. Cases included patients who received a pre-endoscopy drink of NAC and simethicone in 100 mL water administered 10 to 30 minutes prior to UGIE. Controls only had mandatory fasting for 6 to 8 hours prior to UGIE. Propensity score matching was done to ensure comparability between the groups. Digital images were taken at six standard landmarks during UGIE and stored. A blinded investigator subsequently analyzed the images and rated the mucosal visibility on a 3-point scale. The difference in the mean mucosal visibility between the cases and controls was compared. Results Mean mucosal visibility during UGIE was significantly better using NAC with simethicone as compared with no preparation at esophagus (1.14 [0.37] vs. 1.47 [0.62], p < 0.05), gastric fundus (1.10 [0.30] vs. 1.55 [0.64], p < 0.05), gastric body (1.22 [0.50] vs. 1.62 [0.73], p < 0.05), gastric antrum (1.13 [0.37] vs. 1.47 [0.62], p < 0.05), and duodenal bulb (1.13 [0.34] vs. 1.33 [0.56], p < 0.05). In distal duodenum, though visibility improved with NAC with simethicone, the difference was insignificant. There were no adverse events related to the pre-endoscopy drink. Conclusion A pre-endoscopy drink of NAC with simethicone can significantly improve mucosal visibility during UGIE. It is safe, cheap, easily available and maybe considered for routine utilization for ensuring optimal endoscopic outcomes.

Scorecard endoscopy: a pilot study to assess basic skills in trainees for upper gastrointestinal endoscopy

2003 ◽  
Vol 387 (9) ◽  
pp. 386-391 ◽  
Author(s):  
M. Neumann ◽  
T. Siebert ◽  
J. Rausch ◽  
T. Horbach ◽  
C. Ell ◽  
...  
Keyword(s):  
Pilot Study ◽  
Gastrointestinal Endoscopy ◽  
Basic Skills ◽  
Upper Gastrointestinal Endoscopy ◽  
Upper Gastrointestinal
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