scholarly journals Desperate Therapies and the Amazing Race for Antimicrobial Alternatives

2006 ◽  
Vol 17 (5) ◽  
pp. 285-285
Author(s):  
A Mark Joffe

Infectious diseases remain a leading cause of death worldwide. Despite this fact, as well as the increasing recognition that microbial resistance is emerging as a serious threat to human health, antimicrobial research and development are declining. The current situation has evolved through a complex interaction of scientific, economic and regulatory forces. New approaches are needed. If therapies are unavailable or failing, we have only two options: we can prevent infections or we can develop new strategies to deal with them.

Nutrients ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 253 ◽  
Author(s):  
Kathleen Hefferon

The past twenty years have seen the application of biotechnology to generate nutritionally improved food crops. Biofortified rice, cassava, maize, sorghum and other staple crops biofortified with essential micronutrients have great potential to benefit the world’s poor, in terms of both health and economics. This paper describes the use of genetic modification to generate crops that are biofortified with zinc. Examples of zinc-enhanced crops which have been developed using biotechnological approaches will be discussed, and new approaches for research and development will be outlined. The impact of these biofortified crops on human health and well-being will be examined. This paper will conclude with a discussion of the obstacles that must be overcome to enable zinc-fortified crops to be accessible for the world’s malnourished.


Author(s):  
Kpatinde Talagbe Aime ◽  
A. H. Abdul Wahab ◽  
K. S. J. Fadina ◽  
W. K. A. Oting ◽  
D. B. O. Sinatoko

2011 ◽  
Vol 1 (5) ◽  
pp. 1-2
Author(s):  
Lavkush Dwivedi

Infectious diseases and consequent immune imbalancesare major constraint in human health managementthroughout the world. However, in recentdecades enormous efforts have been made to elucidatethe immunomodulatory approaches againstinfectious diseases. Immunomodulation is a therapeuticapproach in which we try to intervene inauto regulating processes of the defense system toadjust the immune response at a desired level.The present special issue on cutting edge issues inImmunomodulation like Immune stimulation, Immunesuppression, Immune potentiating and immunereinforcement summarizes our current understandingof this complex mosaic. The accompanyingselection of recent articles from across theworld provides further insight into this topic. 


Stanovnistvo ◽  
2012 ◽  
Vol 50 (1) ◽  
pp. 89-106
Author(s):  
Ivan Marinkovic

The structure of the leading causes of death in Serbia has considerably changed in the last half century. Diseases which presented the main threat to the population a few decades ago are now at the level of a statistical error. On the one side are causes which drastically changed their share in total mortality in this time interval, while others have shown stability and persistence among the basic causes of death. Acute infectious diseases "have been replaced" with chronic noninfectious diseases, due to the improvement of general and health conditions. One of the consequences of such changes is increased life expectancy and a larger share of older population which resulted in cardiovascular diseases and tumors to dominate more and more in total mortality. Convergent trends in the structure of the leading causes of death in Serbia from the middle of the 20th century are the reasons why there are considerably fewer diseases and causes with a significant rate in total population mortality at the beginning of the 21st century. During the 1950s, there were five groups of diseases and causes which participated individually with more than 10% of population mortality (infectious diseases, heart and circulatory diseases, respiratory diseases, some perinatal conditions and undefined states) while at the beginning of the new century there were only two such groups (cardiovascular diseases and tumors). Identical trends exist in all European countries, as well as in the rest of the developed world. The leading causes of death in Serbia are cardiovascular diseases. An average of somewhat over 57.000 people died annually in the period from 2007 - 2009, which represents 55.5% of total population mortality. Women are more numerous among the deceased and this difference is increasing due to population feminization. The most frequent cause of death in Serbia, after heart and circulatory diseases, are tumors, which caused 21,415 deaths in 2009. Neoplasms are responsible for one fifth of all deaths. Their number has doubled in three decades, from 9,107 in 1975 to about 20,000 at the beginning of the 21st century, whereby tumors have become the fastest growing cause of death. Least changes in absolute number of deaths in the last half century were marked among violent deaths. Observed by gender, men are in average three times more numerous among violent deaths than women. In the middle of the 20th century in Serbia, one third of the deaths caused by violence were younger than 25 and as many as one half were younger than 35 years old. Only one tenth (11%) of total number of violent deaths were from the age group of 65 or older. At the end of the first decade of the 21st century (2009), the share of population younger than 25 in the total number of violent deaths was decreased four times (and amounted to 8%). At the same time, the rate of those older than 65 or more quadrupled (amounted to 39%).


2020 ◽  
Vol 58 (9) ◽  
pp. 72-76
Author(s):  
Solmaz Isaq Rzayeva ◽  

In the article in addition to the description of the state of hydrological and geochemical factors, related to the ecogeographic environment, the influence of the ecological-chemical environment on the spread of public health was revealed. The analysis of the influence of the medical-geographical environment on the occurrence and spread of diseases was given. Key words: hydrology, non-infection diseases, eco-geographical condition, endemic gaiter, infectious diseases, ecology geochemical, environmental, medical geography condition


Author(s):  
Roman Gumzej ◽  
Martin Lipicnik

In a time, when the economic crisis is filling the news, it may seem hard to even think about improvements in terms of research and development, since there are lacking funds even for the reproduction. However, the last economic revolution was born in a crisis. Therefore it is sensible to look at the current situation as an opportunity for the next economic revolution,. bringing the economy a new cycle of development. The potentials for growth with the globalization have been mainly exploited so far, bringing considerable negative consequences into our lives and our environment that have triggered anti-globalist and ecological movements around the world. Now it’s time to think how to make things better and more humane. The main goal of this chapter is to lay the foundation for an advanced-research technological platform for logistics applications networks.


Author(s):  
Manish Kumar Dwivedi ◽  
Suvashish Kumar Pandey ◽  
Prashant Kumar Singh

In modern research, nanotechnology is a very attractive technology and helps to reduce infectious diseases. Nanoparticles have gained significantly more important than the bulk counterparts due to their unique properties. This chapter gives knowledge about the general introduction of nanoparticles with classification and also discussed the effect of nanoparticles impact on public health. Nanotechnology is most widely used to reduced different types of infectious diseases such as bacterial, viral, parasitic diseases, etc. Nanotechnology is applied to detect different types of diseases such as cancer, diabetes, and other diseases. Nanotechnology is a useful technique to develop novel drug delivery systems due to their high specificity, high drug-carrying capacity, and high stability. Nanotechnology can be able to improve human health but on the other hand, we have seen a negative impact on human health and environmental health. The solubility and toxicity of nanoparticles is a major issue worldwide.


Author(s):  
Rashida Ferrand

Infectious diseases remain the leading cause of death in adolescents despite the improvements in public health that have occurred in the past decades. While mortality rates from infections are slowly declining in this age group, an exception is HIV, with HIV-related deaths having tripled in the last decade. As with other infections, the risk of acquiring HIV is partly explained by the biological and physical environment. However, the biological changes and the social and behavioural context of adolescence play an important role in determining risk. Notably, infections can result in long-term complications and consequent disability. While effective methods to prevent and treat many common infections do exist, the major challenges are to make these accessible to adolescents, an age-group that is often neglected by health programmes. In addition, adherence to treatment for chronic infections such as HIV, remains a major barrier to ensuring successful outcomes.


1972 ◽  
Vol 120 (559) ◽  
pp. 647-649 ◽  
Author(s):  
J. I. Jansen

Psychiatric Social Work as a profession with its tradition, training and culture rooted in the Hospital Service, will in all probability soon cease to exist. It would appear that the imminent decease of this profession is not generally known or understood. This account, an expression of much personal regret, is also an attempt to give a background to the current situation. It pays tribute to the medical profession, without whom the Psychiatric Social Workers would never have acquired their specialization and expertise. It has been in hospitals and other allied settings that the Psychiatric Social Workers have practised their professional skills and had the opportunities to keep abreast of clinical progress and new approaches to mental health, so essential to teaching new generations.


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