scholarly journals Synthesis, Spectral Characterization and Evaluation of Pharmacodynamic Activity of Copper and Nickel Complexes of Ethambutol Dihydrochloride

2006 ◽  
Vol 3 (4) ◽  
pp. 274-277 ◽  
Author(s):  
M. Mathrusri Annapurna ◽  
M. E. Bhanoji Rao ◽  
B. V. V. Ravi Kumar
Keyword(s):  
Metal Ion ◽  
Copper Complexes ◽  
Nickel Complexes ◽  
Octahedral Geometry ◽  
Spectral Characterization ◽  
Alamar Blue Assay ◽  
Alamar Blue ◽  
Thermal Data ◽  
Lowenstein Jensen ◽  
Assay Methods

Nickel and copper complexes of ethambutol [EB] were synthesized and characterized. On the basis of spectral and thermal data an octahedral geometry was assigned to the complexes with molecular formulae [Cu(C10H24N2O2)2Cl2] 5H2O and [Ni(C10H24N2O2)2Cl2] 2H2O. Coordination of ethylene diamine derivative to the metal ion was proposed. The anti-tubercular activity of the complexes was evaluated using Lowenstein–Jensen medium and MABA [Microplate Alamar Blue Assay] methods.

Electrochemistry of nickel picket fence porphyrin. Electrogeneration and spectral characterization of nickel complexes in unusual oxidation states

1989 ◽  
Vol 28 (13) ◽  
pp. 2542-2547 ◽  
Author(s):  
K. M. Kadish ◽  
D. Sazou ◽  
G. B. Maiya ◽  
B. C. Han ◽  
Y. M. Liu ◽  
...  
Keyword(s):  
Nickel Complexes ◽  
Spectral Characterization ◽  
Oxidation States ◽  
Picket Fence

A novel isotachophoresis of cobalt and copper complexes by metal ion substitution reaction in a continuous moving chelation boundary

The Analyst ◽  
2010 ◽  
Vol 135 (1) ◽  
pp. 140-148 ◽  
Author(s):  
Wei Zhang ◽  
Jian-Feng Chen ◽  
Liu-Yin Fan ◽  
Cheng-Xi Cao ◽  
Ji-Cun Ren ◽  
...  
Keyword(s):  
Substitution Reaction ◽  
Metal Ion ◽  
Copper Complexes ◽  
Ion Substitution

scholarly journals Synthesis, Structure and Antitumour Properties of a New 1,2-Propylenediaminetetraacetate-Ruthenium(III) Compound

1995 ◽  
Vol 2 (4) ◽  
pp. 211-219 ◽  
Author(s):  
R. Vilaplana ◽  
M. A. Romero ◽  
M. Quirós ◽  
J. M. Salas ◽  
F. González-Vílchez
Keyword(s):  
Metal Ion ◽  
Antitumour Activity ◽  
Octahedral Geometry ◽  
X Ray Diffraction ◽  
Chlorine Atoms ◽  
X Ray ◽  
Human Cancers ◽  
Novel Complex

A novel complex formed by ruthenium (III) and the sequestering ligand 1,2-propylenediaminetetraacetic acid (PDTA) has been synthetized and characterized. The structure of the monomeric compound, studied by X-ray diffraction , shows an almost symmetric octahedral geometry around the metal ion, with two chlorine atoms in a cis conformation. The antitumour activity against a variety of murine and human cancers is reported.

scholarly journals The Influence of Astaxanthin on the Proliferation of Adipose-derived Mesenchymal Stem Cells in Gelatin-Methacryloyl (GelMA) Hydrogels

Materials ◽  
2019 ◽  
Vol 12 (15) ◽  
pp. 2416 ◽  
Author(s):  
Bo Young Choi ◽  
Elna Paul Chalisserry ◽  
Myoung Hwan Kim ◽  
Hyun Wook Kang ◽  
Il-Whan Choi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cellular Proliferation ◽  
Three Dimensional ◽  
Confocal Imaging ◽  
Alamar Blue Assay ◽  
Ratio Test ◽  
Alamar Blue ◽  
Chemical Structures

Recently, astaxanthin, a red lipophilic pigment belonging to the xanthophyllic family of carotenoids, has shown the feasibility of its uses in tissue engineering and regenerative medicine, due to its excellent antioxidant activities and its abilities to enhance the self-renewal potency of stem cells. In this study, we demonstrate the influence of astaxanthin on the proliferation of adipose-derived mesenchymal stem cells in tissue-engineered constructs. The tissue engineered scaffolds were fabricated using photopolymerizable gelatin methacryloyl (GelMA) with different concentrations of astaxanthin. The effects of astaxanthin on cellular proliferation in two-dimensional environments were assessed using alamar blue assay and reverse transcription polymerase chain reaction (RT-PCR). Then, rheological properties, chemical structures and the water absorption of the fabricated astaxanthin-incorporated GelMA hydrogels were characterized using NMR analysis, rheological analysis and a swelling ratio test. Finally, the influence in three-dimensional environments of astaxanthin-incorporated GelMA hydrogels on the proliferative potentials of adipose-derived stem cells was assessed using alamar blue assay and the confocal imaging with Live/dead staining. The experimental results of the study indicate that an addition of astaxanthin promises to induce stem cell potency via proliferation, and that it can be a useful tool for a three-dimensional culture system and various tissue engineering applications.

Nickel complexes of ligands derived from (o-hydroxyphenyl) dichalcogenide: delocalised redox states of nickel and o-chalcogenophenolate ligands

2019 ◽  
Vol 48 (46) ◽  
pp. 17355-17363 ◽  
Author(s):  
Sridhar Banerjee ◽  
Debobrata Sheet ◽  
Subhash Sarkar ◽  
Partha Halder ◽  
Tapan Kanti Paine
Keyword(s):  
Metal Ion ◽  
Nickel Complexes ◽  
Redox States ◽  
Square Planar

The monoanionic square planar S = 1/2 nickel complexes of dianionic o-chalcogenophenolate ligands display delocalised redox states of the metal ion and ligands.

scholarly journals Synthesis, Spectroscopic, and Antimicrobial Studies on Bivalent Nickel and Copper Complexes of Bis(thiosemicrbazone)

2007 ◽  
Vol 2007 ◽  
pp. 1-7 ◽  
Author(s):  
Sulekh Chandra ◽  
Smriti Raizada ◽  
Monika Tyagi ◽  
Archana Gautam
Keyword(s):  
Metal Complexes ◽  
Metal Ion ◽  
Copper Complexes ◽  
Free Ligand ◽  
Antimicrobial Properties ◽  
Molar Conductance ◽  
Spectral Studies ◽  
Central Metal ◽  
Antimicrobial Studies

A series of metal complexes of Cu(II) and Ni(II) having the general composition[M(L)X2]with benzil bis(thiosemicarbazone) has been prepared and characterized by element chemical analysis, molar conductance, magnetic susceptibility measurements, and spectral (electronic, IR, EPR, mass) studies. The IR spectral data suggest the involvement of sulphur and azomethane nitrogen in coordination to the central metal ion. On the basis of spectral studies, an octahedral geometry has been assigned for Ni(II) complexes but a tetragonal geometry for Cu(II) complexes. The free ligand and its metal complexes have been tested in vitro against a number of microorganisms in order to assess their antimicrobial properties.

scholarly journals Bis(propane-1,3-diamine)disaccharinatonickel(II)

2012 ◽  
Vol 68 (4) ◽  
pp. m425-m426 ◽  
Author(s):  
Gökhan Kaştaş ◽  
Can Kocabıyık
Keyword(s):  
Metal Ion ◽  
Crystal Packing ◽  
Chair Conformation ◽  
Membered Ring ◽  
Octahedral Geometry ◽  
Distorted Octahedral Geometry ◽  
Inversion Center ◽  
One Dimensional ◽  
Dimensional Network ◽  
Distorted Octahedral

In the title complex, [Ni(C7H4NO3S)2(C3H10N2)2] or [Ni(sac)2(pen)2] (sac = saccharinate or 1,1,3-trioxo-2,3-dihydro-1λ6,2-benzothiazol-2-ide and pen = propane-1,3-diamine), the NiIIion sits on an inversion center, being coordinated by two N atoms of the sac ligands, which occupytranspositions, and four N atoms of the bidentate pen ligands to define a distorted octahedral geometry. The pen ligands chelate the metal ion, forming a six-membered ring which adopts a half-chair conformation, while the sac ligands adopt the most common coordination mode. The crystal packing is stabilized by N—H...O hydrogen bonds, which form a one-dimensional network along [010]. It is also supported by an N—H...S hydrogen bond between the amine group of the pen ligand and the sulfonyl group of the sac ligand.

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