scholarly journals Gastrocolic Fistulae as a Consequence of Benign Gastric Ulcer Disease

2003 ◽  
Vol 17 (7) ◽  
pp. 441-443 ◽  
Author(s):  
Jeff Marschall ◽  
Richard Bigsby ◽  
Patrik Nechala
Keyword(s):  
Gastric Ulcer ◽  
Rare Entity ◽  
Benign Gastric Ulcer ◽  
First Line ◽  
Barium Enema Examination ◽  
Gastrointestinal Series ◽  
Ulcer Disease ◽  
Presenting Symptoms ◽  
Underlying Malignancy ◽  
Upper Gastrointestinal

Gastrocolic fistulae are a rare entity, occurring most commonly in the context of a malignant process or less frequently as a complication of a benign gastric ulcer. Presenting symptoms tend to be nonspecific, but the diagnosis can be confirmed with near certainty by barium enema examination or an upper gastrointestinal series. Although the management of gastrocolic fistulae has historically been surgical, medical management has recently been recommended as the first line of treatment when an underlying malignancy can be excluded.

A multicenter, randomized, double-blind comparison of Roxatidine with Ranitidine in the treatment of patients with uncomplicated benign gastric ulcer disease

1995 ◽  
Vol 17 (3) ◽  
pp. 467-478 ◽  
Author(s):  
Gerald Brandstätter ◽  
I.N Marks ◽  
Frank Lanza ◽  
David Kogut ◽  
Barton Cobert ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Benign Gastric Ulcer ◽  
Double Blind ◽  
Ulcer Disease ◽  
Blind Comparison

scholarly journals CLINICAL PROFILE AND RISK FACTORS FOR BENIGN PEPTIC ULCER DISEASE IN A TERTIARY CARE CENTRE IN THE SUBHIMALAYAN RANGES OF NORTH INDIA

2020 ◽  
pp. 1-3
Author(s):  
Vishal Bodh ◽  
Rajesh Sharma ◽  
Brij Sharma
Keyword(s):  
Risk Factors ◽  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Peptic Ulcer Disease ◽  
Low Socioeconomic Status ◽  
Low Socioeconomic ◽  
Ulcer Disease ◽  
H Pylori ◽  
Upper Gastrointestinal

Background: To study the clinical profile and risk factors for benign peptic ulcer disease. Material and Methods: A total of 200 patients of peptic ulcer disease (PUD) diagnosed on upper gastrointestinal endoscopy were included. The socio-demographic profile, risk factors, clinical and endoscopic findings were recorded. Results: A total of 200 patients of peptic ulcer disease were included, out of which 168(84%) were males, while 32 (16%) were females. Most of the patients (61%) were between age 31-60 years with mean age of 47 years. Most of patients were farmers from rural areas and belonged to low socioeconomic status. History of smoking and alcohol intake was present in 106(53%) and 70( 35 %) patients respectively.Most common presenting complaints were epigastric pain and/or burning in 72 (36%) , followed by upper abdomen discomfort 70(35%) and upper gastrointestinal bleed 58(29%). Duodenal ulcer (DU) was present in 152 (76%), gastric ulcer(GU) in 30 (15%) while 18 (9%) had both DU and GU. Most of the patients had Forrest III ulcer 167 (83.5%) followed by Forrest IIc ulcer 13 (6.5%). H. pylori was detected by rapid urease test on endoscopic biopsy specimen in 156 (78 % ) of the total 200 patients of peptic ulcer disease. H. pylori was detected in 78.94 % case of DU, 60% case of GU and 100% cases of both DU and GU. Conclusion: PUD is a multifactorial health problem affecting almost all populations worldwide. . The major risk factors associated with PUD included tobacco and alcohol consumption besides low socioeconomic status, rural background and occupation of farming. Our findings indicate the substantial role of H. pylori and painkiller ingestion in the pathogenesis of PUD. Duodenal ulcer is most common type followed by gastric ulcer. Most had Forrest III ulcer followed by Forrest IIc.

Study of Endoscopic Findings in First Episode of Upper Gastrointestinal Bleeding

2021 ◽  
Vol 10 (1) ◽  
pp. 14-19
Author(s):  
Krishna Raj Adhikari ◽  
Rajesh Kumar Mandal
Keyword(s):  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
First Episode ◽  
Gastric Erosion ◽  
Ulcer Disease ◽  
Endoscopic Findings ◽  
Upper Gastrointestinal

Background and Aims: Upper gastrointestinal bleeding (UGIB) is one of the most common and grave emergencies encountered in Emergency department in Tertiary health care centre in our country. Upper endoscopy has a crucial role in the diagnosis and treatment of upper gastrointestinal bleeding. The aim of this study is to assess the endoscopic findings in patients presenting with first episode of UGIB. Methods: This was a hospital based cross sectional study of patients with haematemesis, melena or both who underwent UGI endoscopy at Bir Hospital during January 2019 to January 2020. Patient demographics, site and nature of lesions and risk factors for bleeding were analyzed. Results: Among 72 enrolled patients 48 (66.67 %) were male and 24 (33.3 %) were female. Haematemesis 27% was the most common presenting complain followed by melena 25.5% and fainting/ dizziness 22.5%. Endoscopy was done in all cases and gastric ulcer disease 27.8% was the commonest cause of first episode of UGI bleeding followed by variceal bleeding, gastric erosion and duodenal ulcer, 25%, 16.7%, 12.5% respectively. Conclusions: Peptic ulcer disease was the most common cause of first episode of UGI bleeding in our context. Among peptic ulcer diseases gastric ulcer was more common than duodenal ulcer. Haematemesis and melena were the commonest clinical presentation of UGI bleeding.  

Randomized, double-blind comparison of famotidine with ranitidine in treatment of acute, benign gastric ulcer disease

1989 ◽  
Vol 34 (7) ◽  
pp. 1047-1052 ◽  
Author(s):  
Scott R. Brazer ◽  
Malcolm P. Tyor ◽  
Frank S. Pancotto ◽  
Robert S. Brice ◽  
John T. Garbutt ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Benign Gastric Ulcer ◽  
Double Blind ◽  
Ulcer Disease ◽  
Blind Comparison

scholarly journals Endoscopic findings in patients with uninvestigated dyspepsia: A retrospective study from Qatar

2020 ◽  
Author(s):  
Ahmad Badi ◽  
VAMANJORE ABOOBAKER NAUSHAD ◽  
Nishan Kunnummal Purayil ◽  
Prem Chandra ◽  
Hassan Abu Zaid ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Gastric Carcinoma ◽  
Epigastric Pain ◽  
Age Groups ◽  
Ulcer Disease ◽  
Presenting Symptoms ◽  
Endoscopic Findings ◽  
Predominant Symptom ◽  
Study Population ◽  
Clinically Significant

Abstract Background/Aim: Dyspepsia is a common complaint in general clinical practice. The prevalence of clinically significant findings in endoscopy in dyspeptic subjects of various age groups and ethnicities in Qatar is not well studied. This study aimed to evaluate the prevalence of endoscopic findings in previously uninvestigated patients with dyspepsia. Methods we retrospectively studied subjects older than 18 years of age who underwent endoscopy for dyspeptic complaints from January 2011 to December 2017. Subjects who already had peptic ulcer disease, who underwent endoscopy for reasons other than dyspepsia and those with incomplete data were excluded. Results A total of 824 subjects were reviewed for eligibility and 733 were included for analysis. The mean ± SD age of the study subjects was 42.7 ± 13.5 years and 59.5% were males. Epigastric pain was the predominant symptom (79.2%) followed by heartburn (26.1%). Abnormal endoscopic findings were noted in 91.8% of subjects. Gastritis (65.5%) and esophagitis (33.1%) were the most common findings observed. The overall prevalence of gastric ulcer was 4.6% and it was higher in the subjects above 60 years of age (14.1%, p = 0.001). Gastric carcinoma was seen only in 4 (0.54%) subjects. Conclusion Gastritis was the most common endoscopic finding observed followed by esophagitis. The most common presenting symptoms were epigastric pain and heartburn. The prevalence of gastric ulcer was significantly high in patients above 60 years and gastric carcinoma was low in the study population.

scholarly journals Optimized Self-Nanoemulsifying Delivery System Based on Plant-Derived Oil Augments Alpha-Lipoic Acid Protective Effects Against Experimentally Induced Gastric Lesions

Dose-Response ◽  
2021 ◽  
Vol 19 (1) ◽  
pp. 155932582110012
Author(s):  
Shaimaa M. Badr-Eldin ◽  
Usama A. Fahmy ◽  
Hibah M. Aldawsari ◽  
Osama A. A. Ahmed ◽  
Nabil A. Alhakamy ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Delivery System ◽  
Lipoic Acid ◽  
Tween 80 ◽  
Protective Effects ◽  
Alpha Lipoic Acid ◽  
Ulcer Index ◽  
Ulcer Disease ◽  
Mucosal Defect ◽  
Polyethylene Glycol 200

Peptic ulcer disease is an injury of the alimentary tract that leads to a mucosal defect reaching the submucosa. Alpha-lipoic acid (ALA), a natural potent antioxidant, has been known as a gastroprotective drug yet its low bioavailability may restrict its therapeutic efficacy. This study aimed to formulate and optimize ALA using a self-nanoemulsifying drug delivery system (SNEDDS) with a size of nano-range, enhancing its absorption and augmenting its gastric ulcer protection efficacy. Three SNEDDS components were selected as the design factors: the concentrations of the pumpkin oil (X1, 10–30%), the surfactant tween 80 (X2, 20–50%), and the co-surfactant polyethylene glycol 200 (X3, 30–60%). The experimental design for the proposed mixture produced 16 formulations with varying ALA-SNEDDS formulation component percentages. The optimized ALA-SNEDDS formula was investigated for gastric ulcer protective effects by evaluating the ulcer index and by the determination of gastric mucosa oxidative stress parameters. Results revealed that optimized ALA-SNEDDS achieved significant improvement in gastric ulcer index in comparison with raw ALA. Histopathological findings confirmed the protective effect of the formulated optimized ALASNEDDS in comparison with raw ALA. These findings suggest that formulation of ALA in SNEDDS form would be more effective in gastric ulcer protection compared to pure ALA.

scholarly journals Duodenal imaging on the spotlight: from A to Z

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Carolina Terra ◽  
Daniel Ramos-Andrade ◽  
Ivo Sá-Marques ◽  
Jorge Brito ◽  
Filipe Caseiro-Alves ◽  
...  
Keyword(s):  
Imaging Features ◽  
Upper Gastrointestinal Series ◽  
Alphabetical Order ◽  
Gastrointestinal Series ◽  
Local Extension ◽  
General Radiologist ◽  
Gastrointestinal Radiology ◽  
Close Proximity ◽  
Inflammatory Processes ◽  
Upper Gastrointestinal

AbstractAbdominal computed tomography (CT) is frequently performed to evaluate gastrointestinal pathologic conditions. The majority of the gastrointestinal radiology literature has concentrated on the colon, stomach, and distal small bowel. The duodenum is often overlooked on imaging, namely on CT, but its anatomy (intra and retroperitoneal) and location in such close proximity to other viscera results in involvement by a multitude of primary and secondary processes, some of them exclusive to this bowel segment. While some conditions, like duplications, lipomas, and diverticula, are usually asymptomatic and are incidentalomas that have no pathologic significance, others are symptomatic and very relevant and should be recognized by every general radiologist: development conditions such as annular pancreas and gut malrotation; inflammatory processes such as ulcers and secondary involvement from pancreatitis; neoplastic conditions such as adenocarcinoma, lymphoma, or local extension from adjacent malignancies. They all can be reliably diagnosed with CT. In this article, we demonstrate the typical imaging features of various diseases involving the duodenum, such as developmental, traumatic, inflammatory, infectious, neoplastic, and postsurgical pathologic conditions in alphabetical order, focusing mainly on upper gastrointestinal series (UGIS) and CT but also some radiography, ultrasound, and magnetic resonance (MR) imaging.

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