scholarly journals Thoracic Complications of Lemierre Syndrome

2000 ◽  
Vol 7 (6) ◽  
pp. 481-485 ◽  
Author(s):  
Russell Thomas Gowan ◽  
Reza John Mehran ◽  
Pierre Cardinal ◽  
Gwynne Jones
Keyword(s):  
Jugular Vein ◽  
Fusobacterium Necrophorum ◽  
Review Of The Literature ◽  
Septic Thrombophlebitis ◽  
Lemierre Syndrome ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Oropharyngeal Infection ◽  
Gram Negative Bacillus ◽  
The Subject

Lemierre syndrome is a severe, septicemic illness most commonly caused by the anaerobic Gram-negative bacillusFusobacterium necrophorum. It is characterized by an acute oropharyngeal infection, with secondary septic thrombophlebitis of the internal jugular vein and frequent metastatic infections. This report of a patient with the Lemierre syndrome is complemented by a review of the literature on the subject.

MENINGITIS IN PREMATURE INFANTS

PEDIATRICS ◽  
1949 ◽  
Vol 4 (4) ◽  
pp. 479-483
Author(s):  
B. M. KAGAN ◽  
J. H. HESS ◽  
B. MIRMAN ◽  
EVELYN LUNDEEN
Keyword(s):  
Premature Infant ◽  
Premature Infants ◽  
Spinal Fluid ◽  
Review Of The Literature ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus ◽  
The Subject ◽  
Symptoms And Signs

A review of the literature on the subject of meningitis in premature infants revealed 45 cases. In 10 of these cases from which bacterial agents were cultured, six showed a gram negative bacillus. Twelve additional cases are added in this study and Esch. coli was cultured from the spinal fluid of nine (with another organism in three of the nine cases). The symptoms and signs of meningitis in premature infants are discussed. No reports have been found in the literature of recovery from meningitis in premature infants weighing less than 2,500 gm. The course and treatment of a premature infant who weighed less than 1,000 gm. and who recovered from an Esch. coli meningitis is described in detail.

Lemierre Syndrome: Not So Forgotten!

2014 ◽  
Vol 23 (2) ◽  
pp. 176-179 ◽  
Author(s):  
Nishant Gupta ◽  
Stephen M. Kralovic ◽  
Dennis McGraw
Keyword(s):  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Lymphatic Vessels ◽  
Fusobacterium Necrophorum ◽  
Septic Thrombophlebitis ◽  
Lemierre Syndrome ◽  
Travel History ◽  
Life Threatening Illness ◽  
Life Threatening ◽  
Bedside Ultrasonography

Lemierre syndrome is a rare and life-threatening illness. Often referred to as “the forgotten disease,” its incidence is reported to be as low as 1 in a million. The microorganism responsible for Lemierre syndrome is typically Fusobacterium necrophorum. The bacterium starts in the pharynx and peritonsillar tissue, then disseminates through lymphatic vessels. Severe sepsis rapidly develops, as does the hallmark of this syndrome: septic thrombophlebitis of the internal jugular vein. This report describes a case of Lemierre syndrome in a previously healthy 26-year-old man with life-threatening internal jugular vein thrombophlebitis following 2 weeks of an indolent course of pharyngitis. The patient’s initial presentation and extensive travel history as an Army veteran were particularly challenging aspects in establishing his diagnosis. The diagnosis of Lemierre syndrome is frequently delayed. Routine use of bedside ultrasonography may aid in rapid diagnosis of the disease.

scholarly journals Dokdonella KoreensisBacteremia: A Case Report and Review of the Literature

2014 ◽  
Vol 25 (5) ◽  
pp. 255-256 ◽  
Author(s):  
Boeun Lee ◽  
Mitchell R Weinstein
Keyword(s):  
Case Report ◽  
Hematological Malignancy ◽  
Review Of The Literature ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus

Dokdonella koreensisis a non-spore-forming, aerobic, Gram-negative bacillus that was initially isolated from soil. The pathogenicity of this organism in humans remains unclear. The authors report a case of successfully treatedD koreensisbacteremia in a patient with a hematological malignancy who presented with a fever and palmar-plantar erythrodysesthesia.

scholarly journals A Global Overview of β-lactam Resistance Genes in Klebsiella pneumoniae

2019 ◽  
Vol 11 (1) ◽  
pp. 22-34
Author(s):  
Yone da Silva ◽  
Rafaela Ferrari ◽  
Victor Augustus Marin ◽  
Carlos Adam Conte Junior
Keyword(s):  
Klebsiella Pneumoniae ◽  
Resistance Genes ◽  
Public Interest ◽  
Bacterial Isolate ◽  
Public Health Problem ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus ◽  
The Subject ◽  
Over Time

Klebsiella pneumoniae is a gram-negative bacillus of the Enterobacteriaceae family, commonly associated with nosocomial infections. This pathogen is a serious public health problem as some of its strains are resistant to about 95% antimicrobials of the pharmaceutical market. This resistance is promoted by the production of the β-lactamase extended spectrum (ESBL) enzymes, one of the major causes of therapeutic failure. This review evaluated the incidence and distribution of resistance genes from Klebsiella pneumoniae to β-lactams worldwide. Our study was conducted with the subject the organism K. pneumoniae and β-lactamic resistance. The most reported genes were blaSHV-12, blaCTX-M-2 and blaSHV-5; with blaSHV-12 being the most described. The last two were present in all continents, characterizing its cosmopolitan profiles. The greatest genetic diversity was observed in the Asian and Oceania, where 41 different genes were isolated. Additionally, our review points out the coexistence of different classes of β-lactamases in a single bacterial isolate. Finally, knowledge of mechanisms associated with resistance of K. pneumoniae is of great public interest and the verification of resistance genes shows a variation over time and location highlights the importance of evaluating the mechanisms or strategies by which these variations occur.

Lemierre’s Syndrome

2021 ◽  
pp. 1-2
Author(s):  
Abduallah Mawkili ◽  
Keyword(s):  
Young Adults ◽  
Group A Streptococcus ◽  
Fusobacterium Necrophorum ◽  
Adolescents And Young Adults ◽  
Lemierre’S Syndrome ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus ◽  
Group A ◽  
Lemierre's Syndrome

Fusobacterium necrophorum is a non-spore forming anaerobic gram-negative bacillus and has traditionally been associated with Lemierre’s syndrome, an infectious thrombophlebitis of the internal jugular vein.Fusobacterium necrophorum is commonly associated with pharyngitis, tonsillitis and peritonsillar abscesses similar to that of group A streptococcus, and is accounted for up to 10% of cases of pharyngitis in adolescents and young adults

scholarly journals Lemierre’s Syndrome: A Complication of Cervicofacial Cellulitis in a Child

2021 ◽  
pp. 1-3
Author(s):  
Mohamed Ali GLITI ◽  
◽  
Lina EL Messaoudi ◽  
Sophia Nitassi ◽  
Bencheikh Razika ◽  
...  
Keyword(s):  
Jugular Vein ◽  
Chest Ct ◽  
Blood Cultures ◽  
Septic Thrombophlebitis ◽  
Lemierre’S Syndrome ◽  
Pediatric Case ◽  
Lemierre Syndrome ◽  
Oropharyngeal Infection ◽  
The Right ◽  
Lemierre's Syndrome

Introduction: Lemierre’s syndrome complicates oropharyngeal infection and associates septic thrombophlebitis of the internal jugular vein with sepsis and distant septic emboli (especially pulmonary). We report a pediatric case with thrombophlebitis of the jugular vein in the context of cervicofacial cellulitis. Summary of the Clinical Case: A 2-year-old girl consulted in the emergency room for angina complicated by right cervicofacial cellulitis with thrombosis of the right jugular vein. The diagnosis of atypical Lemierre syndrome was made and the patient received first medical treatment (antibiotic therapy, anticoagulation) allowing a cure without sequelae. And secondary surgical treatment (adenoidectomy and tonsillectomy). Discussion: The presence of a cervical venous thrombosis complicating an oropharyngeal infection should lead to a search for Lemierre’s syndrome (blood cultures and chest CT) rare but serious and require immediate treatment

scholarly journals Lemierre syndrome presenting as acute mastoiditis in a 2-year-old girl with congenital dwarfism

2015 ◽  
Vol 7 (2) ◽  
Author(s):  
Jason B. Fischer ◽  
Andrew Prout ◽  
R. Alexander Blackwood ◽  
Kavita Warrier
Keyword(s):  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Fusobacterium Necrophorum ◽  
Septic Thrombophlebitis ◽  
Computed Tomography Scan ◽  
Older Children ◽  
Acute Mastoiditis ◽  
Lemierre Syndrome ◽  
Congenital Dwarfism ◽  
Tomography Scan

Lemierre syndrome is defined by septic thrombophlebitis of the internal jugular vein caused by <em>Fusobacterium</em>. Historically, these infections originate from the oropharynx and typically are seen in older children, adolescents and young adults. More recently, otogenic sources in younger children have been described with increasing frequency. We present a case of a two-year old, who initially developed an otitis media with perforation of the tympanic membrane and went on to develop mastoiditis and non-occlusive thrombosis of the venous sinus and right internal jugular vein. <em>Fusobacterium necrophorum</em> was grown from operative cultures of the mastoid, ensuing computed tomography scan revealed occlusion of the internal jugular vein and the patient was successfully treated with clindamycin, ciprofloxacin and enoxaparin. This case demonstrates the importance of considering <em>Fusobacterium</em> in otogenic infections and the consideration of Lemierre syndrome when <em>F. necrophorum</em> is identified.

Complicated otitis media caused by Fusobacterium necrophorum

2004 ◽  
Vol 118 (1) ◽  
pp. 50-53 ◽  
Author(s):  
W. Giridharan ◽  
S. De ◽  
E. Z. Osman ◽  
L. Amma ◽  
J. Hughes ◽  
...  
Keyword(s):  
Otitis Media ◽  
Internal Jugular Vein ◽  
High Mortality ◽  
Jugular Vein ◽  
Fusobacterium Necrophorum ◽  
Primary Sources ◽  
Aetiological Agent ◽  
Septic Thrombophlebitis ◽  
Oropharyngeal Infection ◽  
Sources Of Infection

Fusobacterium necrophorum is implicated as an aetiological agent in a variety of necrotic diseases, such as Lemièrre’s syndrome (LS) in humans. LS was initially described as septic thrombophlebitis of the internal jugular vein secondary to an acute oropharyngeal infection. Other primary sources of infection include parotitis, otitis media, sinusitis, odontogenic infection and m stoiditis. In the pre-antibiotic era LS carried a high mortality. This has been reduced as a result of the widespread use of antibiotics, butthere is still a definite morbidity and mortality associated with infection with this virulent organism. We report three cases of complicatedotitis media caused by Fusobacterium necrophorum. The patients were treated successively with intravenous metronidazole and surgery.

scholarly journals Sore Throat, Fever, Septic Emboli, and Acute Respiratory Distress Syndrome: A Case of Lemierre Syndrome

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Farrukh N. Jafri ◽  
Jodi Shulman ◽  
José C. Gómez-Márquez ◽  
Matthew Lazarus ◽  
David M. Ginsburg
Keyword(s):  
Sore Throat ◽  
Distress Syndrome ◽  
Jugular Vein ◽  
Septic Thrombophlebitis ◽  
Chest Discomfort ◽  
Lemierre Syndrome ◽  
Septic Emboli ◽  
Oropharyngeal Infection ◽  
Progression Of Disease ◽  
Prompt Diagnosis

Lemierre’s syndrome is an acute oropharyngeal infection with a secondary septic thrombophlebitis of the internal jugular vein (IVJ) that was first reported in literature in 1936. It involves the progression of disease from a focal suppurative peritonsillar infection to a local septic thrombophlebitis with hematogenous progression to and distant septic emboli. It is a rare and potentially fatal syndrome requiring prompt diagnosis and management. We present the case progression of an 18-year-old male who presented to our hospital with resolved sore throat, fever, and chest discomfort who experienced a sharp clinical decline. His case, physical exam, laboratory abnormalities, and radiologic studies highlight important facets of this rare but important syndrome.

scholarly journals Bipolar staining of gram-negative bacillus in cerebrospinal fluid

Blood ◽  
2014 ◽  
Vol 124 (18) ◽  
pp. 2892-2892
Author(s):  
Lori D. Racsa ◽  
Eileen M. Burd
Keyword(s):  
Cerebrospinal Fluid ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus
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