scholarly journals Small Bowel Review: Part I

1996 ◽  
Vol 10 (3) ◽  
pp. 179-189
Author(s):  
ABR Thomson ◽  
JA Thomson ◽  
MJ Ropeleski ◽  
GE Wild

Major scientific advances have been made over the past few years in the areas of small bowel physiology, pathology, microbiology and clinical sciences. Over 1000 papers have been reviewed and a selective number are considered here. Wherever possible, the clinical relevance of these advances have been identified. There have been a number of important and/or interesting developments in the past year that have clinical significance.

1996 ◽  
Vol 10 (4) ◽  
pp. 261-273
Author(s):  
ABR Thomson ◽  
JA Thomson ◽  
MJ Ropeleski ◽  
GE Wild

Major scientific advances have been made over the past few years in the areas of small bowel physiology, pathology, microbiology and clinical sciences. Over 1000 papers have been reviewed and a selective number are considered here. Wherever possible, the clinical relevance of these advances have been identified. Topics discussed are enterocyte proliferation and growth factors; amino acids, peptides and allergies; motility; salt and water absorption and secretion – diarrhea; vitamins and minerals; early development and ageing of the intestine; and ethanol effects.


2014 ◽  
Vol 42 (2) ◽  
pp. 190-207 ◽  
Author(s):  
Lisa Eckstein ◽  
Jeremy R. Garrett ◽  
Benjamin E. Berkman

Over the past decade, there has been an extensive debate about whether researchers have an obligation to disclose genetic research findings, including primary and secondary findings. There appears to be an emerging (but disputed) view that researchers have some obligation to disclose some genetic findings to some research participants. The contours of this obligation, however, remain unclear.As this paper will explore, much of this confusion is definitional or conceptual in nature. The extent of a researcher's obligation to return secondary and other research findings is often limited by reference to terms and concepts like “incidental,” “analytic validity,” “clinical validity,” “clinical relevance,” “clinical utility,” “clinical significance,” “actionability,” and “desirability.” These terms are used in different ways by different writers to describe obligations in different sorts of cases.


2010 ◽  
Vol 21 (2) ◽  
pp. 187-194
Author(s):  
Colleen Trevino

Strategies for the management of small bowel obstructions have changed significantly over the years. Nonoperative medical management has become the mainstay of treatment of many small bowel obstructions. However, the key to the management of small bowel obstructions is identifying those patients who need surgical intervention. Identification of those at risk for bowel ischemia and bowel death is an art as much as it is a science. Using the current literature and the past knowledge regarding small bowel obstructions, the clinician must carefully identify the signs and symptoms that suggest the need for operative intervention. Classification of the obstruction, history and physical examination, imaging, response to decompression and resuscitation, and resolution or progression of symptoms are the key factors influencing the management of small bowel obstructions.


Gerontology ◽  
2021 ◽  
pp. 1-5
Author(s):  
Arjen Mol ◽  
Marieke Esmé Charlotte Blom ◽  
Danique Johanna van den Bosch ◽  
Richard Jack Anton Van Wezel ◽  
Carel G.M. Meskers ◽  
...  

<b><i>Background:</i></b> Orthostatic hypotension (OH) and impaired OH recovery derived from beat-to-beat blood pressure (BP) measurements are associated with detrimental clinical outcome, but the clinical relevance of OH recovery assessed using the widely available sphygmomanometer is still unclear. <b><i>Method:</i></b> 635 geriatric outpatients underwent comprehensive geriatric assessment, including orthostatic BP measurements using a sphygmomanometer, during supine rest and 1 and 3 min after standing up and assessment of physical performance (i.e., the timed up and go test and the Short Physical Performance Battery) and the number of falls in the past year. The association between BP recovery, defined as BP at 3 min minus BP at 1 min after standing up, with physical performance and falls was assessed using regression analyses, adjusting for age and sex, both in the entire cohort and after stratifying for the presence of OH at 1 min after standing up. <b><i>Results:</i></b> BP recovery was not associated with physical performance or number of falls, neither in the entire cohort, nor in subpopulations with or without OH. <b><i>Conclusion:</i></b> The clinical relevance of BP recovery between 1 and 3 min after standing up could not be demonstrated. The results suggest that sphygmomanometer measurements have an inadequate time resolution to record the clinically relevant dynamics of orthostatic BP recovery.


2019 ◽  
Vol 178 (2) ◽  
pp. 33-37
Author(s):  
V. P. Zemlyanoy ◽  
A. B. Singaevskiy ◽  
D. V. Gladyshev ◽  
N. M. Vryblevskiy ◽  
E. M. Nesvit ◽  
...  

The objective is to study acute perforated ulcers of the small bowel, which arise as a complication after operations on the abdominal and pelvic organs.Material and methods. A retrospective analysis of patient’s cases whose postoperative period was complicated by the development of acute perforated ulcers of small bowel.Results. Over the past 20 years, the frequency of this complication increased by 8 times. In the structure of primary nosology, various types of oncological diseases prevail (69.4 %), moreover most patients underwent emergency operations. Most often, this complication occurred on the 4–10th day of the postoperative period, and the ulcers were multiple. Among these patients, there was an extremely high mortality rate of 74.2 %.Conclusion. Considering the significant increase in the number of this complication in recent years and the high level of mortality among patients, a detailed study of acute perforated ulcers of the small intestine of the postoperative period is necessary.


2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Saptarshi Biswas ◽  
Shekhar Gogna ◽  
Prem Patel

Type IV paraesophageal hernia (PEH) is very rare and is characterized by the intrathoracic herniation of the abdominal viscera other than the stomach into the chest. We describe a case of a 90-year-old male patient who presented at our emergency department complaining of epigastric pain that he had experienced over the past few hours and getting progressively worse. On the day after admission, his pain became severe. Chest radiography revealed an intrathoracic intestinal gas bubble; emergency exploratory laparotomy identified a type IV PEH with herniation of only the jejunum with perforated diverticula on mesenteric side through a hiatal defect into mediastinum. There are a few published cases of small bowel herniation into the thoracic cavity in the literature. Our patient represents a rare case of an individual diagnosed with type IV PEH with herniation of jejunum with perforated diverticula.


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