scholarly journals Psychiatric Sequelae of Organophosphorous Poisoning: A Case Study and Review of the Literature

1994 ◽  
Vol 7 (3-4) ◽  
pp. 117-122 ◽  
Author(s):  
R. H. Bradwell

This is the case of a young farm worker presenting with episodes of acute organic psychosis superimposed on a state of chronic anergy and hypersomnia. It is suggested that he developed an encephalopathic illness presenting with an organic bipolar affective disorder as a result of organophosphate exposure. In proposing this aetiology, an hypothesis is developed which links clinical observations and investigative results with research findings in relation to organophosphorus compounds and neuropharmacology.

1987 ◽  
Vol 151 (6) ◽  
pp. 853-855 ◽  
Author(s):  
Stephen F. Signer ◽  
Richard P. Swinson

Two female patients with longstanding bipolar affective disorder demonstrated de Clérambault's paradigm of erotomania during the euthymic phase of their illness. Although a diagnosis of schizophrenia or paranoid disorder is often given, a review of the literature shows that many cases have features of a major affective disorder, probably bipolar affective disorder and its spectrum.


Author(s):  
Leonid Bardenshtein ◽  
Natalia Osipova

The review is devoted to diagnosing bipolar affective disorder in adolescence. The article summarizes the domestic and foreign research findings concerning the early disease manifestations, the specific features of the disease course, and the relationship with mental and corporal comorbidity. Special attention is paid to the diagnosis of hypomania, based on the recommendations of modern international diagnostic systems: DSM-V (APA, 2013), and the draft International Classification of Diseases, ICD-11 2019. Early detection of affective disorder in adolescents using screening study methods is shown to be significant.


1988 ◽  
Vol 152 (3) ◽  
pp. 354-358 ◽  
Author(s):  
A. Poynton ◽  
P. K. Bridges ◽  
J. R. Bartlett

The results of stereotactic subcaudate tractotomy in nine patients with resistant bipolar affective disorder are presented in the form of a single case study with a summary of the other eight cases. Follow-up studies at 2–4 years showed substantial improvement in five patients and amelioration of symptoms in a further four patients, with a tendency for a greater improvement in the manic than in the depressive episodes. These preliminary results suggest that there is a place for this operation in the management of severe bipolar affective disorders which are not responding to any other treatment, although decisive recovery occurs less often than with unipolar depression.


2001 ◽  
Vol 31 (4) ◽  
pp. 427-432 ◽  
Author(s):  
F. Pfeffer ◽  
M. Grube

Objective: An extraordinary case of an organic psychosis during the treatment of a patient with a bipolar affective disorder. Methods: Clinical observation and further investigations including monitoring of serum levels (case report). Results: A significant interaction between venlafaxine and propafenone causes markedly increased serum levels of venlafaxine correlating with unexpected psychopathological changes. Conclusions: There is a potentially dangerous interaction between venlafaxine and propafenone. Serum levels of venlafaxine should be monitored if propafenone is added.


2000 ◽  
Vol 12 (3) ◽  
pp. 99-103 ◽  
Author(s):  
T. Lloyd ◽  
P.B. Jones

ABSTRACTThe past 20 years have seen much research into affective disorders, reflecting advances in both pharmacological and psychological treatments. However, there has been little basic epidemiological research into bipolar illness. This is particularly apparent regarding its basic occurrence and possible epigenetic causes. This presentation will attempt to bring together and integrate the available evidence regarding the basic epidemiology of bipolar disorder, define areas where further research is needed, and outline a large epidemiological study including bipolar affective disorder that has been supported by the Stanley Foundation.


2020 ◽  
Vol 13 (6) ◽  
pp. e235007
Author(s):  
Timothy Yap ◽  
Jacquita S Affandi ◽  
Christopher M Reid ◽  
Dan Xu

A case of a 59-year-old man with resistant hypertension, despite 8 months of non-pharmacological and pharmacological management up to maximal doses of triple antihypertensive therapy. Review of the literature found a study that reported improved blood pressure control with bedtime dosing of antihypertensive treatment. Changing to bedtime dosage of antihypertensives resulted in significant improvement in blood pressure control to below target levels. This highlights the importance of the clinicians’ awareness and implementation of research findings and hence delivery of best evidence-based care.


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