scholarly journals Biliary Duct Granular Cell Tumor: A Rare But Surgically Curable Benign Tumor

HPB Surgery ◽  
1993 ◽  
Vol 6 (4) ◽  
pp. 311-317 ◽  
Author(s):  
W. David Lewis ◽  
Joseph F. Buell ◽  
Roger L. Jenkins ◽  
Peter A. Burke
Keyword(s):  
Granulosa Cell ◽  
Granular Cell Tumor ◽  
Granulosa Cell Tumor ◽  
Granular Cell ◽  
Surgical Excision ◽  
Biliary Tree ◽  
Cell Tumor ◽  
The Body ◽  
Benign Tumors ◽  
Biliary Duct

Granulosa cell tumors are rare benign tumors which may be found throughout the body. Rare cases are isolated within the biliary tree. If completely resected, surgical excision is curative.A case of biliary duct granulosa cell tumor is presented with review of the world’s literature on this topic.

scholarly journals Granular cell tumor of the common hepatic duct presenting as cholangiocarcinoma and acute acalculous cholecystitis

2008 ◽  
Vol 55 (4) ◽  
pp. 99-101 ◽  
Author(s):  
D. Bilanovic ◽  
I. Boricic ◽  
D. Zdravkovic ◽  
T. Randjelovic ◽  
N. Stanisavljevic ◽  
...  
Keyword(s):  
Granular Cell Tumor ◽  
Hepatic Duct ◽  
Acalculous Cholecystitis ◽  
Granular Cell ◽  
Biliary Tree ◽  
Cell Tumor ◽  
Common Hepatic Duct ◽  
Benign Tumors ◽  
Acute Acalculous Cholecystitis ◽  
Extrahepatic Biliary Tree

Granular cell tumors (GCT) are rare benign tumors. Less than 1% of GCTs involve the extrahepatic biliary tree. Most researches favor a Schwann cell origin. Patient, caucasion, female, 31 year old presented with 4 month history of painless jaundice and pruritus. US and CT revealed dilatation of intrahepatic biliary tree and surgery was performed. Firm tumor mass was found above the conjunction of cystic duct and common hepatic duct (CHD) that caused obstruction and gallblader empyema. The patient underwent radical surgical procedure because Klatskin tumor was clinically suspected. Patohystology and immunohistochemistry confirmed granular cell tumor. Eight years after surgery the patient is wellbeing without symptoms. To our knowledge 69 cases of GCT of the extrahepatic biliary tree have been reported and none of the acute acalculous cholecystitis case accompanied by GCT of CHD. Granular cell tumors are rarely diagnosed preoperatively. Wide resection offers the best chance for cure.

scholarly journals Granular Cell Tumor over the Mons Pubis: An Uncommon Tumor

2019 ◽  
Vol 2019 ◽  
pp. 1-3 ◽  
Author(s):  
M. Patabendige ◽  
D. J. Wickramasooriya ◽  
L. Dasanayake
Keyword(s):  
Soft Tissue ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumor ◽  
The Body ◽  
Complete Surgical Excision ◽  
Neural Origin ◽  
Labium Majus ◽  
Uncommon Tumor

Granular cell tumors are uncommon, usually benign, soft tissue neoplasms of neural origin. They occur throughout the body; vulval involvement is uncommon and labium majus is the commonest site in vulva. Complete surgical excision is the preferred treatment of choice to prevent recurrence. Here, we present a benign granular cell tumor over the mons pubis of vulva in a 27-year-old woman.

Oral granular cell tumors: an analysis of 10 new pediatric and adolescent cases and a review of the literature

2005 ◽  
Vol 29 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Robert Brannon ◽  
Payal Anand
Keyword(s):  
English Language ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumor ◽  
Review Of The Literature ◽  
Soft Tissue Neoplasm ◽  
Adolescent Population ◽  
Male Ratio ◽  
Common Location

Clinicopathologic studies on the granular cell tumor, a submucosal benign soft-tissue neoplasm, have not addressed the pediatric and adolescent population. This study of patients from birth to 19 years of age describes clinically and microscopically 10 new cases and combines them with 24 well-documented pediatric cases previously published in the English-language literature. Of the 34, patient ages ranged from 3 to 19 years (mean age 14.5 years) with a female-to-male ratio of 3.3 to 1. The most common location was the tongue (50%) and lips (25%). In neoplasms whose epithelial findings were documented microscopically, a reactive pseudoepitheliomatous (pseudocarcinomatous) hyperplasia of the overlying epithelium occurred in 29%. The recurrence rate was less than 10% following conservative surgical excision. This study reveals that an oral granular cell tumor in the first decade of life is an uncommon event and discusses the importance of differentiating between squamous cell carcinoma and granular cell tumor.

Granular Cell Tumor of the Biliary Tree: A Rare Cause of Limy Bile

1990 ◽  
Vol 7 (2) ◽  
pp. 122-124 ◽  
Author(s):  
Milton A. Gumbs ◽  
Guillermo P. Narvaez, Jr. ◽  
Adel Faltaous ◽  
Ye Hum Kim ◽  
Paul H. Gerst
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Biliary Tree ◽  
Cell Tumor ◽  
Limy Bile

scholarly journals A Rare Case of Granular Cell Tumor of the Anal Region: Diagnostic Difficulty to Masses in the Anal Area

2014 ◽  
Vol 99 (1) ◽  
pp. 45-47 ◽  
Author(s):  
Takaaki Fujii ◽  
Hiroki Morita ◽  
Satoru Yamaguchi ◽  
Soichi Tsutsumi ◽  
Takayuki Asao ◽  
...  
Keyword(s):  
Rare Case ◽  
Granular Cell Tumor ◽  
Polypoid Lesion ◽  
Granular Cell ◽  
Clinical Findings ◽  
Japanese Woman ◽  
Cell Tumor ◽  
The Body ◽  
Current Case ◽  
Anal Region

Abstract Granular cell tumor may be located anywhere in the body; however, the gastrointestinal tract is infrequently involved and anal granular cell tumors are extremely rare. We report herein a rare case of granular cell tumor in the anal region. In the current case, a 66-year-old Japanese woman was found to have a polypoid lesion in the anus with hemorrhoids. The mass detected as an anal polypoid lesion with ulceration was resected and diagnosed as granular cell tumor by histologic examination. Granular cell tumor of the anal region is rare, and benign perianal polypoid lesions are relatively uncommon clinical findings. They might present diagnostic challenges to surgeons and pathologists. Awareness of the differential diagnosis of granular cell tumor and careful microscopic examination might allow proper management and diagnosis.

scholarly journals A Rare Case of a Metastatic Malignant Abrikossoff Tumor

2021 ◽  
pp. 1868-1875
Author(s):  
Mohamed Tayeb Salaouatchi ◽  
Sandra De Breucker ◽  
Héloise Rouvière ◽  
Véronique Lesage ◽  
Laureen Jeanne Armande Rocq ◽  
...  
Keyword(s):  
Granular Cell Tumor ◽  
Soft Tissues ◽  
Granular Cell ◽  
Cell Tumor ◽  
Benign Tumors ◽  
Large Size ◽  
Positron Emission ◽  
History Of ◽  
Malignant Granular Cell Tumor ◽  
Malignant And Benign Tumors

Abrikossoff tumor, also called granular cell tumor (GCT), is a neoplasm of the soft tissues which is most commonly a solitary, painless, and benign tumor. However, 2% of Abrikossoff tumors can be malignant. We report here the case of a 75-year-old male who presented a local recurrence of Abrikossoff tumor of the left thigh. The anatomopathological analysis concluded to a malignant GCT, and the F-18 fluorodeoxyglucose positron emission tomography showed multiple lesions in the lymph nodes and bones. The potential conversion to malignancy should alert practitioners because of the extremely poor prognosis. The diagnosis of malignant granular cell tumor should be based on a bundle of clinical and histological features and not solely on histologic features because of the challenging distinction between malignant and benign tumors due to the lack of well-defined criteria for the diagnosis of malignancy. Large size and recurrence are the most important clinical features predicting malignant behavior. Patients with a history of Abrikossoff tumor should be followed closely to monitor recurrence and malignant transformation. The apparent originality of our observation – which could lie in the evolution of a GCT tumor, initially considered as benign, to a malignant form – has to be challenged regarding the issue of classifying some cases according to the classical “benign” and “malignant” dichotomy.

scholarly journals Granular cell tumor that originated in a posterior ethmoid sinus

2017 ◽  
Vol 3 (3) ◽  
pp. 721
Author(s):  
Myung Woo Kim ◽  
Sun Hee Chang ◽  
Ick Soo Choi
Keyword(s):  
Nasal Cavity ◽  
Nasal Polyp ◽  
Granular Cell Tumor ◽  
Neuron Specific Enolase ◽  
Granular Cell ◽  
Ethmoid Sinus ◽  
Cell Tumor ◽  
The Body ◽  
Eosinophilic Cytoplasm ◽  
The Right

<p class="abstract"><span lang="EN-US">A granular cell tumor (GCT) is a rare neoplasm. It grows slowly, presumably originates from a Schwann cell, and is typically benign. Histopathologically, GCTs are composed of loosely infiltrating sheets of large, pale, polyhedral cells with abundant granular eosinophilic cytoplasm and a pale, centrally situated nucleus. Immunohistochemically, GCTs express the S-100 protein and neuron-specific enolase. A GCT can occur anywhere in the body. Half of all GCTs occur in the head and neck regions, especially on the tongue, but they are rarely found in the nasal cavity. A GCT usually arises as a solitary tumor and can be confirmed only by a histologic examination. The appropriate treatment is excision of the lesion. </span>Here, we present a rare case of a GCT originating in the right posterior ethmoid sinus in the nasal cavity. A GCT originating in a posterior ethmoid sinus has not been reported thus far. In our case, a simple nasal polyp was found in the left ethmoid sinus of the patient. Thus, we initially misjudged the GCT in the right nasal cavity as a simple nasal polyp.</p>

scholarly journals Pediatric Granular Cell Tumor of the Breast: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Nathan P. Heinzerling ◽  
Shannon M. Koehler ◽  
Sara Szabo ◽  
Amy J. Wagner
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Excisional Biopsy ◽  
Cell Tumor ◽  
The Body ◽  
Positive Staining ◽  
Review Of The Literature ◽  
Rare Presentation ◽  
Breast Masses

Objective. Granular cell tumors arise from neurogenic mesenchymal stem cells and can occur anywhere throughout the body. They rarely present as breast masses and should be included in the differential diagnosis of pediatric breast neoplasms. We report a rare presentation of a pediatric breast granular cell tumor and a review of the literature.Participant. A 15-year-old female presented with an enlarging breast mass. She underwent ultrasound imaging and excisional biopsy, which revealed a granular cell tumor. Granular cell tumors of the breast are difficult to diagnose using ultrasound and mammography due to numerous similarities to other breast masses. Histopathologic staining best differentiates breast granular cell tumors from other breast masses with their positive staining for S100, CD68, and neurospecific enolase.Conclusion. Although rare, granular cell tumors of the breast should be considered as a possible diagnosis for pediatric breast masses to allow for proper management and follow-up for these patients. Although rare, these tumors do have malignant potential necessitating a correct and timely diagnosis.

A CASE REPORT OF MULTIPLE GRANULAR CELL TUMORS OF TONGUE WITH REVIEW OF LITERATURE.

2021 ◽  
pp. 27-28
Author(s):  
Anish Poorna T ◽  
Ramya A ◽  
Joshna EK ◽  
Bobby John
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Hard Palate ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
The Body ◽  
Review Of Literature ◽  
Architectural Patterns ◽  
Malignant Lesions

Also called as Abrikossoff's tumor, the granular cell tumor (GCT) can occur in any part of the body, most of them occur in the head and neck especially in the tongue, cheek and palate. Almost three fourth of the lesions seen in head and neck are present over the tongue, oral mucosa or hard palate. Both benign and malignant lesions have been reported; although occurrence of malignancy is rare, comprising of 2% of all granular cell tumors. Here we present a case report of granular cell tumor of tongue at two different sites in a 17-year-old girl with a brief review of literature on granular cell tumors. Although oral GCTs exhibit a benign behavior they may demonstrate a wide variety of features and architectural patterns. Rather than a true neoplasm, GCTs could be regarded as lesions that reect a local metabolic or reactive change.

Perianal Granular Cell Tumor: Report of a Case and Review of the Literature

2009 ◽  
Vol 95 (4) ◽  
pp. 538-541 ◽  
Author(s):  
Massimiliano Mistrangelo ◽  
Paola Cassoni ◽  
Gitana Scozzari ◽  
Isabella Castellano ◽  
Giorgia Gavello ◽  
...  
Keyword(s):  
Literature Search ◽  
Granular Cell Tumor ◽  
Clinical Course ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumor ◽  
Pathological Examination ◽  
Perianal Region ◽  
Therapeutic Procedures

Introduction Granular cell tumor was first described by Abrikossoff in 1926. Over the years several cases of this neoplasm have been reported, with a variety of localizations. We here report a case of perianal granular cell tumor and discuss its histogenesis and its relevance to clinical practice. Methods The clinical course and histopathology of the case are reviewed, and a literature search for other reported cases has been performed. Results A 46-year-old woman presented with a perianal nodular lesion. Pathological examination revealed a granular cell tumor. A literature search produced only 25 other cases of anal and perianal granular cell tumors. Conclusions Granular cell tumors are rarely observed in the perianal region. Their existence must always be borne in mind in the differential diagnosis of perianal neoplasms. In most cases surgical excision is curative, but potential malignant transformation must be considered during therapeutic procedures and follow-up.

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