scholarly journals Parental HLA Sharing, Feto-Maternal Compatibility and Neonatal Birthweight in Families With a History of Recurrent Spontaneous Abortion

1993 ◽  
Vol 11 (2-3) ◽  
pp. 125-130 ◽  
Author(s):  
D. C. Kilpatrick ◽  
W. A. Liston

The mean birthweight of babies eventually born to couples with a history of recurrent spontaneous abortion (RSA) is allegedly lower if the parents have a high degree of HLA antigen sharing (Reznikoff-Etievantet al., 1991), but this relationship has not been independently confirmed. We have re-investigated this question by analysing data from 36 families. In 22 instances, we were able to relate birthweight directly to feto-maternal HLA compatibility for the first time in such families. We were unable to confirm any appreciable influence of paternal or feto-maternal HLA sharing on birthweight or placental weight and conclude that RSA families do not differ markedly from normal families in this respect.

1989 ◽  
Vol 19 (1) ◽  
pp. 11-14 ◽  
Author(s):  
S A Bwala

The case records of 53 consecutive Nigerian inpatients with stroke in the University of Maiduguri Teaching Hospital, Maiduguri were retrospectively reviewed. The mean age at presentation was 55 years and the male to female ratio was 2.5: 1. The mean duration of symptoms before presentation was 11.1 weeks and the average duration of stay in hospital was 3 weeks. Thirty-three (63%) of the lesions were infarctive and 19 (37%) were haemorrhagic. Only 3 (6%) patients gave a history of prior transient ischaemic attacks (TIAs). Forty-two (79%) patients were hypertensive at presentation out of which 27 (64%) had the hypertension diagnosed for the first time. Four (8%) patients were non-insulin dependent diabetics. There were 11 hospital deaths (21%). Thus hypertension, more than half undiagnosed at admission, was the most common risk factor for stroke in the hospital population studied.


2014 ◽  
Vol 73 (4) ◽  
pp. 927-940 ◽  
Author(s):  
Dilip K. Basu

Editor's Note: The essay that follows is based on a conference paper by Dilip K. Basu that has long circulated informally, in the process exercising an unusually high degree of influence for an unpublished commentary. Most notably, some ideas embedded in it have been spread via literary scholar Lydia Liu's engagement with and quoting of the paper inThe Clash of Empires: The Invention of China in Modern World Making(Liu 2006), a provocative and much-cited book that calls for a radical rethinking of some of the standard terms and concepts used in the past to refer to the Qing Empire's ties to and conflicts with other political and territorial units. Those familiar with Liu's work will find here an essay that complements some arguments in her book; those who have not read it will be introduced to those ideas for the first time. Beyond this, though, all readers will find a discussion of various ideas and events—visions of China's place in the world, how the story of the Opium War is thought about in different settings, the history of Sinology—shaped by personal as well as scholarly concerns.The essay's ties to the author's life and associations, which come into play more as the essay proceeds, make it a good fit with the goals of our recently introduced and still evolving “Reflections” genre. In addition, since it revisits critically ideas about China associated with the work of John K. Fairbank, it can be placed well beside some of the essays published in the “Legacies” series launched by Kenneth George, in his time as editor of the journal. And regular attendees of the Association for Asian Studies annual meetings may notice that much that follows resonates with the keynote address by Amitav Ghosh, one of those familiar with Basu's essay in draft form, when that conference was held in Toronto in 2012. The pages that follow are tightly focused on China, but Basu's discussion of “xenology” (a term for the ways that cultures think about those deemed “others,” which has, of course, the same root as the more familiar term “xenophobia”) clearly has implications for widely varied times and places, just as the handling of Fairbank's distinctive role in Chinese studies may bring to mind parallels to the influence that other prominent Western academics from the last century once shaped and via their legacies can continue to shape academic work on other parts of Asia. While focused tightly on China, in other words, it has much to offer readers whose primary interest is not in that country.


2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Ying Cui ◽  
Ling He ◽  
Chun-Yan Yang ◽  
Qian Ye

Abstract Background Early recurrent spontaneous abortion (ERSA) is a common condition in pregnant women. To prevent ERSA is necessary to look for abortion indicators, such as hormones and proteins, in an early stage. Methods Thirty patients with ERSA were enrolled in the case group. In the control group, we recruited 30 healthy women without a history of miscarriage undergoing voluntary pregnancy termination. The differentially expressed proteins in the serum were identified between the two groups using PRM and iTRAQ. Results Seventy-eight differentially expressed proteins were identified. Using GO functional annotation and KEGG pathway analysis, we detected that the most significant changes occurred in the pathway of Fc gamma R-mediated phagocytosis. Meanwhile, using PRM, we identified three proteins that were closely related to abortion, B4DTF1 (highly similar to PSG1), P11464 (PSG1), and B4DF70 (highly similar to Prdx-2). The levels of B4DTF1 and P11464 were down-regulated, while the level of B4DF70 was up-regulated. Conclusions CD45, PSG1, and Prdx-2, were significantly dysregulated in the samples of ERSA and could become important biomarkers for the prediction and diagnosis of ERSA. Larger‑scale studies are required to confirm the diagnostic value of these biomarkers.


2007 ◽  
Vol 55 (2) ◽  
pp. 97-107 ◽  
Author(s):  
Mónica Susana Hoffmeyer ◽  
María Sonia Barría de Cao

In this study we investigate for the first time the zooplankton assemblages in a relatively small tidal channel called Bahía del Medio, situated in the middle-outer area of the Bahía Blanca Estuary, South of the Main channel. We focused the study on micro- and mesozooplankton assemblages with emphasis on tintinnids, copepods and meroplankton along the annual cycle 1997-1998. Fifteen species of tintinnids belonging to 6 genera were observed in the study area, the mean total tintinnid abundance fluctuating between 3.4 x 10(6) ind. m-3 and 5.1 x 10(6) ind m-3. The mesozooplankton comprised 11 taxa, total abundance fluctuating between 449 ind m-3 in March 1997 and only 1 ind m-3 in October 1997. The channel proved to be spatially homogeneous in its physical and biochemical features. Micro- and mesozooplankton abundance displayed a high degree of spatial homogeneity, though the seasonal variation in both environment and zooplankton was significant. Comparison with the zooplankton observed at a station in the Main channel of the estuary showed differences in number of taxa represented, a general lower abundance of both assemblages and the presence of some rare species, a fact which is discussed.


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