Corticocortical connections in the visual system: structure and function

1995 ◽  
Vol 75 (1) ◽  
pp. 107-154 ◽  
Author(s):  
P. A. Salin ◽  
J. Bullier
Keyword(s):  
Visual System ◽  
Structure And Function ◽  
System Structure ◽  
Corticocortical Connections ◽  
And Function

Neural system-enriched gene expression: relationship to biological pathways and neurological diseases

2004 ◽  
Vol 18 (2) ◽  
pp. 167-183 ◽  
Author(s):  
Jianhua Zhang ◽  
Amy Moseley ◽  
Anil G. Jegga ◽  
Ashima Gupta ◽  
David P. Witte ◽  
...  
Keyword(s):  
Gene Expression ◽  
Nervous System ◽  
Intracellular Signaling ◽  
Large Scale ◽  
Expression Profiles ◽  
Gene List ◽  
Structure And Function ◽  
System Structure ◽  
Psychiatric Disease ◽  
And Function

To understand the commitment of the genome to nervous system differentiation and function, we sought to compare nervous system gene expression to that of a wide variety of other tissues by gene expression database construction and mining. Gene expression profiles of 10 different adult nervous tissues were compared with that of 72 other tissues. Using ANOVA, we identified 1,361 genes whose expression was higher in the nervous system than other organs and, separately, 600 genes whose expression was at least threefold higher in one or more regions of the nervous system compared with their median expression across all organs. Of the 600 genes, 381 overlapped with the 1,361-gene list. Limited in situ gene expression analysis confirmed that identified genes did represent nervous system-enriched gene expression, and we therefore sought to evaluate the validity and significance of these top-ranked nervous system genes using known gene literature and gene ontology categorization criteria. Diverse functional categories were present in the 381 genes, including genes involved in intracellular signaling, cytoskeleton structure and function, enzymes, RNA metabolism and transcription, membrane proteins, as well as cell differentiation, death, proliferation, and division. We searched existing public sites and identified 110 known genes related to mental retardation, neurological disease, and neurodegeneration. Twenty-one of the 381 genes were within the 110-gene list, compared with a random expectation of 5. This suggests that the 381 genes provide a candidate set for further analyses in neurological and psychiatric disease studies and that as a field, we are as yet, far from a large-scale understanding of the genes that are critical for nervous system structure and function. Together, our data indicate the power of profiling an individual biologic system in a multisystem context to gain insight into the genomic basis of its structure and function.

Nervous System Structure and Function

Neurology ◽  
2016 ◽  
pp. 11-67
Author(s):  
Charles Clarke ◽  
Roger Lemon
Keyword(s):  
Nervous System ◽  
Structure And Function ◽  
System Structure ◽  
And Function

Electronic Equipment Fault Diagnosis Expert System Based on PDA/HPC

2013 ◽  
Vol 683 ◽  
pp. 925-928
Author(s):  
Lei Lei ◽  
Jian Hu Zhang ◽  
Wei Peng ◽  
Yong Wu ◽  
Lin Tao Li
Keyword(s):  
Fault Diagnosis ◽  
Reference Value ◽  
Structure And Function ◽  
Database Management System ◽  
Electronic Equipment ◽  
System Structure ◽  
Development Platform ◽  
Technical Realization ◽  
Fault Diagnosis System ◽  
And Function

In order to develope and research fault diagnosis platform of one electronic equipment, this paper mainly expound the equipment fault diagnosis system based on PDA/HPC structure and function as well as the development platform technology, introduce database management system structure and realization based on PDA/HPC. The successfully developed exepert system is of great significance to improve repair guarantee ability of the electronic equipment and its technical realization and application has model significance and reference value.

Sign in / Sign up

Export Citation Format

Share Document