scholarly journals Modeling autonomic regulation of cardiac function and heart rate variability in human endotoxemia

2011 ◽  
Vol 43 (16) ◽  
pp. 951-964 ◽  
Author(s):  
Jeremy D. Scheff ◽  
Panteleimon D. Mavroudis ◽  
Steven E. Calvano ◽  
Stephen F. Lowry ◽  
Ioannis P. Androulakis
Keyword(s):  
Mathematical Model ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Stress Responses ◽  
Acute Stress ◽  
Inflammatory Diseases ◽  
Biological Processes ◽  
Cellular Mechanisms ◽  
Human Endotoxemia ◽  
The Relationship

Heart rate variability (HRV), the quantification of beat-to-beat variability, has been studied as a potential prognostic marker in inflammatory diseases such as sepsis. HRV normally reflects significant levels of variability in homeostasis, which can be lost under stress. Much effort has been placed in interpreting HRV from the perspective of quantitatively understanding how stressors alter HRV dynamics, but the molecular and cellular mechanisms that give rise to both homeostatic HRV and changes in HRV have received less focus. Here, we develop a mathematical model of human endotoxemia that incorporates the oscillatory signals giving rise to HRV and their signal transduction to the heart. Connections between processes at the cellular, molecular, and neural levels are quantitatively linked to HRV. Rhythmic signals representing autonomic oscillations and circadian rhythms converge to modulate the pattern of heartbeats, and the effects of these oscillators are diminished in the acute endotoxemia response. Based on the semimechanistic model developed herein, homeostatic and acute stress responses of HRV are studied in terms of these oscillatory signals. Understanding the loss of HRV in endotoxemia serves as a step toward understanding changes in HRV observed clinically through translational applications of systems biology based on the relationship between biological processes and clinical outcomes.

The relationship between autonomic function and heart rate variability in human endotoxemia

2013 ◽  
Vol 28 (6) ◽  
pp. e32
Author(s):  
Jeremy Scheff ◽  
Siobhan Corbett ◽  
Steve Calvano ◽  
Ioannis Androulakis
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Autonomic Function ◽  
Human Endotoxemia ◽  
The Relationship

scholarly journals Stress Watch: The Use of Heart Rate and Heart Rate Variability to Detect Stress: A Pilot Study Using Smart Watch Wearables

Sensors ◽  
2021 ◽  
Vol 22 (1) ◽  
pp. 151
Author(s):  
Taryn Chalmers ◽  
Blake Anthony Hickey ◽  
Phillip Newton ◽  
Chin-Teng Lin ◽  
David Sibbritt ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Stress Response ◽  
General Population ◽  
Stress Responses ◽  
Acute Stress ◽  
Stress Test ◽  
Biological Stress ◽  
Stress States ◽  
The Individual

Stress is an inherent part of the normal human experience. Although, for the most part, this stress response is advantageous, chronic, heightened, or inappropriate stress responses can have deleterious effects on the human body. It has been suggested that individuals who experience repeated or prolonged stress exhibit blunted biological stress responses when compared to the general population. Thus, when assessing whether a ubiquitous stress response exists, it is important to stratify based on resting levels in the absence of stress. Research has shown that stress that causes symptomatic responses requires early intervention in order to mitigate possible associated mental health decline and personal risks. Given this, real-time monitoring of stress may provide immediate biofeedback to the individual and allow for early self-intervention. This study aimed to determine if the change in heart rate variability could predict, in two different cohorts, the quality of response to acute stress when exposed to an acute stressor and, in turn, contribute to the development of a physiological algorithm for stress which could be utilized in future smartwatch technologies. This study also aimed to assess whether baseline stress levels may affect the changes seen in heart rate variability at baseline and following stress tasks. A total of 30 student doctor participants and 30 participants from the general population were recruited for the study. The Trier Stress Test was utilized to induce stress, with resting and stress phase ECGs recorded, as well as inter-second heart rate (recorded using a FitBit). Although the present study failed to identify ubiquitous patterns of HRV and HR changes during stress, it did identify novel changes in these parameters between resting and stress states. This study has shown that the utilization of HRV as a measure of stress should be calculated with consideration of resting (baseline) anxiety and stress states in order to ensure an accurate measure of the effects of additive acute stress.

The Relationship Between Mindfulness and Heart Rate Variability

2010 ◽  
Author(s):  
Erin V. Rodgers ◽  
Raymond Fleming ◽  
Aaryn R. Schuster
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
The Relationship

The Relationship between Heart Rate Variability and Metabolic Syndrome at a Rural Area

2004 ◽  
Vol 16 (4) ◽  
pp. 459
Author(s):  
Kyoung Bok Min ◽  
Jin Young Min ◽  
Kyung Hee Jung-Choi ◽  
Hyung Joon Jhun ◽  
Sung Il Cho ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Rural Area ◽  
The Relationship

scholarly journals Indices of Heart Rate Variability and Performance During a Response-Conflict Task Are Differently Associated With ADHD and Autism

2021 ◽  
pp. 108705472097279
Author(s):  
Alessio Bellato ◽  
Iti Arora ◽  
Puja Kochhar ◽  
Chris Hollis ◽  
Madeleine J. Groom
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Sensory Information ◽  
Response Conflict ◽  
Mediation Model ◽  
Conflict Task ◽  
Accurate Performance ◽  
And Performance ◽  
Comorbid Adhd ◽  
The Relationship

We investigated autonomic arousal, attention and response conflict, in ADHD and autism. Heart rate variability (HRV), and behavioral/electrophysiological indices of performance, were recorded during a task with low and high levels of response conflict in 78 children/adolescents (7–15 years old) with ADHD, autism, comorbid ADHD+autism, or neurotypical. ANOVA models were used to investigate effects of ADHD and autism, while a mediation model was tested to clarify the relationship between ADHD and slower performance. Slower and less accurate performance characterized ADHD and autism; however, atypical electrophysiological indices differently characterized these conditions. The relationship between ADHD and slower task performance was mediated by reduced HRV in response to the cue stimulus. Autonomic hypo-arousal and difficulties in mobilizing energetic resources in response to sensory information (associated with ADHD), and atypical electrophysiological indices of information processing (associated with autism), might negatively affect cognitive performance in those with ADHD+autism.

Perceived Social Support and Heart Rate Variability: An Integrative Review

2021 ◽  
pp. 019394592110289
Author(s):  
Madison P. Goodyke ◽  
Patricia E. Hershberger ◽  
Ulf G. Bronas ◽  
Susan L. Dunn
Keyword(s):  
Social Support ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Stress Response ◽  
Health Care Professionals ◽  
Acute Stress ◽  
Perceived Social Support ◽  
Included Study ◽  
Integrative Review ◽  
Stress Buffering

The purpose of this integrative review is to explore and synthesize literature about the relationship between perceived social support and cardiac vagal modulation, measured by heart rate variability (HRV), during phases of an acute stress response to assess this potential relationship underlying the stress-buffering effects of perceived social support. A systematic search of seven databases was conducted, including MEDLINE, CINAHL, PsychINFO, Embase, ProQuest, medRxiv, and clinicaltrials.gov. Eight studies met the inclusion criteria and were systematically synthesized. A quality appraisal was completed for each included study. Majority of studies focused on time and frequency domain measures of HRV thought to reflect parasympathetic modulation of heart rate and identified them as positively associated with perceived social support during rest, stress induction, and recovery from an acute stressor. Results highlight the importance for nurses and other health care professionals to assess patients’ perceived social support, as increased perceived social support may contribute to an adaptive stress response.

scholarly journals The relationship between Gulf War Illness symptom severity and heart rate variability: A pilot study

Life Sciences ◽  
2021 ◽  
pp. 119663
Author(s):  
Kyle J. Jaquess ◽  
Nathaniel Allen ◽  
Timothy J. Chun ◽  
Lucas Crock ◽  
Alexander A. Zajdel ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Pilot Study ◽  
Symptom Severity ◽  
Gulf War ◽  
Gulf War Illness ◽  
The Relationship

scholarly journals The relationship between heart rate variability and inflammatory markers in cardiovascular diseases

2008 ◽  
Vol 33 (10) ◽  
pp. 1305-1312 ◽  
Author(s):  
Alexander Haensel ◽  
Paul J. Mills ◽  
Richard A. Nelesen ◽  
Michael G. Ziegler ◽  
Joel E. Dimsdale
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Cardiovascular Diseases ◽  
Inflammatory Markers ◽  
The Relationship
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