scholarly journals Multifaceted aspects of chunking enable robust algorithms

2014 ◽  
Vol 112 (8) ◽  
pp. 1849-1856 ◽  
Author(s):  
Daniel E. Acuna ◽  
Nicholas F. Wymbs ◽  
Chelsea A. Reynolds ◽  
Nathalie Picard ◽  
Robert S. Turner ◽  
...  

Sequence production tasks are a standard tool to analyze motor learning, consolidation, and habituation. As sequences are learned, movements are typically grouped into subsets or chunks. For example, most Americans memorize telephone numbers in two chunks of three digits, and one chunk of four. Studies generally use response times or error rates to estimate how subjects chunk, and these estimates are often related to physiological data. Here we show that chunking is simultaneously reflected in reaction times, errors, and their correlations. This multimodal structure enables us to propose a Bayesian algorithm that better estimates chunks while avoiding overfitting. Our algorithm reveals previously unknown behavioral structure, such as an increased error correlations with training, and promises a useful tool for the characterization of many forms of sequential motor behavior.

Author(s):  
David A. Atchison ◽  
Carol A. Pedersen ◽  
Stephen J. Dain ◽  
Joanne M. Wood

We investigated the effect of color-vision deficiency on reaction times and accuracy of identification of traffic light signals. Participants were 20 color-normal and 49 color-deficient males, the latter divided into subgroups of different severity and type. Participants performed a tracking task. At random intervals, stimuli simulating standard traffic light signals were presented against a white background at 5° to right or left. Participants identified stimulus color (red/yellow/green) by pressing an appropriate response button. Mean response times for color normals were 525, 410, and 450 ms for red, yellow, and green lights, respectively. For color deficients, response times to red lights increased with increase in severity of color deficiency, with deutans performing worse than protans of similar severity: response times of deuteranopes and protanopes were 53% and 35% longer than those of color normals. A similar pattern occurred for yellow lights, with deuteranopes and protanopes having increased response times of 85% and 53%, respectively. For green lights, response times of all groups were similar. Error rates showed patterns similar to those of response times. Contrary to previous studies, deutans performed much worse than protans of similar severity. Actual or potential applications of this research include traffic signal design and driver licensing.


Author(s):  
T. M. Weatherby ◽  
P.H. Lenz

Crustaceans, as well as other arthropods, are covered with sensory setae and hairs, including mechanoand chemosensory sensillae with a ciliary origin. Calanoid copepods are small planktonic crustaceans forming a major link in marine food webs. In conjunction with behavioral and physiological studies of the antennae of calanoids, we undertook the ultrastructural characterization of sensory setae on the antennae of Pleuromamma xiphias.Distal mechanoreceptive setae exhibit exceptional behavioral and physiological performance characteristics: high sensitivity (<10 nm displacements), fast reaction times (<1 msec latency) and phase locking to high frequencies (1-2 kHz). Unusual structural features of the mechanoreceptors are likely to be related to their physiological sensitivity. These features include a large number (up to 3000) of microtubules in each sensory cell dendrite, arising from or anchored to electron dense rods associated with the ciliary basal body microtubule doublets. The microtubules are arranged in a regular array, with bridges between and within rows. These bundles of microtubules extend far into each mechanoreceptive seta and terminate in a staggered fashion along the dendritic membrane, contacting a large membrane surface area and providing a large potential site of mechanotransduction.


2020 ◽  
Vol 36 (2) ◽  
pp. 296-302 ◽  
Author(s):  
Luke J. Hearne ◽  
Damian P. Birney ◽  
Luca Cocchi ◽  
Jason B. Mattingley

Abstract. The Latin Square Task (LST) is a relational reasoning paradigm developed by Birney, Halford, and Andrews (2006) . Previous work has shown that the LST elicits typical reasoning complexity effects, such that increases in complexity are associated with decrements in task accuracy and increases in response times. Here we modified the LST for use in functional brain imaging experiments, in which presentation durations must be strictly controlled, and assessed its validity and reliability. Modifications included presenting the components within each trial serially, such that the reasoning and response periods were separated. In addition, the inspection time for each LST problem was constrained to five seconds. We replicated previous findings of higher error rates and slower response times with increasing relational complexity and observed relatively large effect sizes (η2p > 0.70, r > .50). Moreover, measures of internal consistency and test-retest reliability confirmed the stability of the LST within and across separate testing sessions. Interestingly, we found that limiting the inspection time for individual problems in the LST had little effect on accuracy relative to the unconstrained times used in previous work, a finding that is important for future brain imaging experiments aimed at investigating the neural correlates of relational reasoning.


2019 ◽  
Author(s):  
Joe Butler ◽  
Samuel Ngabo ◽  
Marcus Missal

Complex biological systems build up temporal expectations to facilitate adaptive responses to environmental events, in order to minimise costs associated with incorrect responses, and maximise the benefits of correct responses. In the lab, this is clearly demonstrated in tasks which show faster response times when the period between warning (S1) and target stimulus (S2) on the previous trial was short and slower when the previous trial foreperiod was long. The mechanisms driving such higher order effects in temporal preparation paradigms are still under debate, with key theories proposing that either i) the foreperiod leads to automatic modulation of the arousal system which influences responses on the subsequent trial, or ii) that exposure to a foreperiod results in the creation of a memory trace which is used to guide responses on the subsequent trial. Here we provide data which extends the evidence base for the memory accounts, by showing that previous foreperiod exposures are cumulative with reaction times shortening after repeated exposures; whilst also demonstrate that the higher order effects associated with a foreperiod remain active for several trials.


Viruses ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1338
Author(s):  
Morgan E. Meissner ◽  
Emily J. Julik ◽  
Jonathan P. Badalamenti ◽  
William G. Arndt ◽  
Lauren J. Mills ◽  
...  

Human immunodeficiency virus type 2 (HIV-2) accumulates fewer mutations during replication than HIV type 1 (HIV-1). Advanced studies of HIV-2 mutagenesis, however, have historically been confounded by high background error rates in traditional next-generation sequencing techniques. In this study, we describe the adaptation of the previously described maximum-depth sequencing (MDS) technique to studies of both HIV-1 and HIV-2 for the ultra-accurate characterization of viral mutagenesis. We also present the development of a user-friendly Galaxy workflow for the bioinformatic analyses of sequencing data generated using the MDS technique, designed to improve replicability and accessibility to molecular virologists. This adapted MDS technique and analysis pipeline were validated by comparisons with previously published analyses of the frequency and spectra of mutations in HIV-1 and HIV-2 and is readily expandable to studies of viral mutation across the genomes of both viruses. Using this novel sequencing pipeline, we observed that the background error rate was reduced 100-fold over standard Illumina error rates, and 10-fold over traditional unique molecular identifier (UMI)-based sequencing. This technical advancement will allow for the exploration of novel and previously unrecognized sources of viral mutagenesis in both HIV-1 and HIV-2, which will expand our understanding of retroviral diversity and evolution.


BMC Chemistry ◽  
2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Arefeh Dehghani Tafti ◽  
Bi Bi Fatemeh Mirjalili ◽  
Abdolhamid Bamoniri ◽  
Naeimeh Salehi

AbstractNano-eggshell/Ti(IV) as a novel naturally based catalyst was prepared, characterized and applied for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives. The characterization of nano-eggshell/Ti(IV) was performed using Fourier Transform Infrared spectroscopy, X-ray Diffraction, Field Emission Scanning Electron Microscopy, Energy-Dispersive X-ray Spectroscopy, and Thermo Gravimetric Analysis. Dihydropyrano[2,3-c]pyrazoles were synthesized in the presence of nano-eggshell/Ti(IV) via a four component reaction of aldehydes, ethyl acetoacetate, malononitrile and hydrazine hydrate at room temperature under solvent free conditions. The principal affairs of this procedure are mild condition, short reaction times, easy work-up, high yields, reusability of the catalyst and the absence of toxic organic solvents.


2021 ◽  
Vol 11 (3) ◽  
pp. 292 ◽  
Author(s):  
Krishn Bera ◽  
Anuj Shukla ◽  
Raju S. Bapi

Motor skill learning involves the acquisition of sequential motor movements with practice. Studies have shown that we learn to execute these sequences efficiently by chaining several elementary actions in sub-sequences called motor chunks. Several experimental paradigms, such as serial reaction task, discrete sequence production, and m × n task, have investigated motor chunking in externally specified sequencing where the environment or task paradigm provides the sequence of stimuli, i.e., the responses are stimulus driven. In this study, we examine motor chunking in a class of more realistic motor tasks that involve internally guided sequencing where the sequence of motor actions is self-generated or internally specified. We employ a grid-navigation task as an exemplar of internally guided sequencing to investigate practice-driven performance improvements due to motor chunking. The participants performed the grid-sailing task (GST) (Fermin et al., 2010), which required navigating (by executing sequential keypresses) a 10 × 10 grid from start to goal position while using a particular type of key mapping between the three cursor movement directions and the three keyboard buttons. We provide empirical evidence for motor chunking in grid-navigation tasks by showing the emergence of subject-specific, unique temporal patterns in response times. Our findings show spontaneous chunking without pre-specified or externally guided structures while replicating the earlier results with a less constrained, internally guided sequencing paradigm.


Author(s):  
Edita Poljac ◽  
Ab de Haan ◽  
Gerard P. van Galen

Two experiments investigated the way that beforehand preparation influences general task execution in reaction-time matching tasks. Response times (RTs) and error rates were measured for switching and nonswitching conditions in a color- and shape-matching task. The task blocks could repeat (task repetition) or alternate (task switch), and the preparation interval (PI) was manipulated within-subjects (Experiment 1) and between-subjects (Experiment 2). The study illustrated a comparable general task performance after a long PI for both experiments, within and between PI manipulations. After a short PI, however, the general task performance increased significantly for the between-subjects manipulation of the PI. Furthermore, both experiments demonstrated an analogous preparation effect for both task switching and task repetitions. Next, a consistent switch cost throughout the whole run of trials and a within-run slowing effect were observed in both experiments. Altogether, the present study implies that the effects of the advance preparation go beyond the first trials and confirms different points of the activation approach ( Altmann, 2002) to task switching.


2007 ◽  
Vol 105 (2) ◽  
pp. 514-522 ◽  
Author(s):  
Joy L. Hendrick ◽  
Jamie R. Switzer

As some states allow motorists to use hands-free cell phones only while driving, this study was done to examine some braking responses to see if conversing on these two types of cell phones affects quick responding. College-age drivers ( n = 25) completed reaction time trials in go/no-go situations under three conditions: control (no cell phone or conversation), and conversing on hands-free and hand-held cell phones. Their task involved moving the right foot from one pedal to another as quickly as possible in response to a visual signal in a lab setting. Significantly slower reaction times, movement times, and total response times were found for both cell phone conditions than for the control but no differences between hands-free and hand-held phone conditions. These findings provide additional support that talking on cell phones, regardless if it is hands-free or hand-held, reduces speed of information processing.


PeerJ ◽  
2016 ◽  
Vol 4 ◽  
pp. e2184 ◽  
Author(s):  
Jim Lumsden ◽  
Andy Skinner ◽  
Andy T. Woods ◽  
Natalia S. Lawrence ◽  
Marcus Munafò

Computerised cognitive assessments are a vital tool in the behavioural sciences, but participants often view them as effortful and unengaging. One potential solution is to add gamelike elements to these tasks in order to make them more intrinsically enjoyable, and some researchers have posited that a more engaging task might produce higher quality data. This assumption, however, remains largely untested. We investigated the effects of gamelike features and test location on the data and enjoyment ratings from a simple cognitive task. We tested three gamified variants of the Go-No-Go task, delivered both in the laboratory and online. In the first version of the task participants were rewarded with points for performing optimally. The second version of the task was framed as a cowboy shootout. The third version was a standard Go-No-Go task, used as a control condition. We compared reaction time, accuracy and subjective measures of enjoyment and engagement between task variants and study location. We found points to be a highly suitable game mechanic for gamified cognitive testing because they did not disrupt the validity of the data collected but increased participant enjoyment. However, we found no evidence that gamelike features could increase engagement to the point where participant performance improved. We also found that while participants enjoyed the cowboy themed task, the difficulty of categorising the gamelike stimuli adversely affected participant performance, increasing No-Go error rates by 28% compared to the non-game control. Responses collected online vs. in the laboratory had slightly longer reaction times but were otherwise very similar, supporting other findings that online crowdsourcing is an acceptable method of data collection for this type of research.


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