Amelia Earhart, alveolar mechanics, and other great mysteries

2012 ◽  
Vol 112 (6) ◽  
pp. 935-936 ◽  
Author(s):  
Gary F. Nieman
Keyword(s):  
Alveolar Mechanics

EFFECTS OF ALVEOLAR MORPHOLOGY ON ALVEOLAR MECHANICS: AN EXPERIMENTAL STUDY OF MOUSE LUNG BASED ON TWO- AND THREE-DIMENSIONAL IMAGING METHODS

2019 ◽  
Vol 19 (04) ◽  
pp. 1950027
Author(s):  
TIANYA LIU ◽  
YUXING WANG ◽  
XIAOYU LIU ◽  
LAN YUAN ◽  
DEYU LI ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Shape Change ◽  
Imaging Techniques ◽  
Three Dimensional ◽  
Spherical Shape ◽  
Mouse Lung ◽  
Three Dimensional Imaging ◽  
Lung Injuries ◽  
Mouse Lungs ◽  
Alveolar Mechanics

Understanding alveolar mechanics is important for preventing the possible lung injuries during mechanical ventilation. Alveolar clusters with smaller size are found having lower compliance in two-dimensional studies. But the influence of alveolar shape on compliance is unclear. In order to investigate how alveolar morphology affects their behavior, we tracked subpleural alveoli of isolated mouse lungs during quasi-static ventilation using two- and three-dimensional imaging techniques. Results showed that alveolar clusters with smaller size and more spherical shape had lower compliance. There was a better correlation of sphericity rather than circularity with alveolar compliance. The compliance of clusters with great shape change was larger than that with relatively slight shape change. These findings suggest the contribution of lung heterogeneous expansion to lung injuries associated with mechanical ventilation.

Dynamic alveolar mechanics in acute lung injury

2010 ◽  
Vol 38 (1) ◽  
pp. 344-345 ◽  
Author(s):  
Gary Nieman ◽  
Louis Gatto
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Alveolar Mechanics

Dynamic alveolar mechanics and ventilator-induced lung injury

2005 ◽  
Vol 33 (Supplement) ◽  
pp. S122-S128 ◽  
Author(s):  
David Carney ◽  
Joseph DiRocco ◽  
Gary Nieman
Keyword(s):  
Lung Injury ◽  
Ventilator Induced Lung Injury ◽  
Alveolar Mechanics

Alveolar mechanics alter hypoxic pulmonary vasoconstriction*

2002 ◽  
Vol 30 (6) ◽  
pp. 1315-1321 ◽  
Author(s):  
Ulysse G. McCann ◽  
Henry J. Schiller ◽  
Louis A. Gatto ◽  
Jay M. Steinberg ◽  
David E. Carney ◽  
...  
Keyword(s):  
Hypoxic Pulmonary Vasoconstriction ◽  
Pulmonary Vasoconstriction ◽  
Alveolar Mechanics

Comparison of two in vivo microscopy techniques to visualize alveolar mechanics

2009 ◽  
Vol 23 (5) ◽  
pp. 323-332 ◽  
Author(s):  
Johannes Bickenbach ◽  
Rolf Dembinski ◽  
Michael Czaplik ◽  
Sven Meissner ◽  
Arata Tabuchi ◽  
...  
Keyword(s):  
In Vivo Microscopy ◽  
Microscopy Techniques ◽  
Alveolar Mechanics
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