scholarly journals WISE 2005: Aerobic and resistive countermeasures prevent paraspinal muscle deconditioning during 60-day bed rest in women

2016 ◽  
Vol 120 (10) ◽  
pp. 1215-1222 ◽  
Author(s):  
Jacquelyn A. Holt ◽  
Brandon R. Macias ◽  
Suzanne M. Schneider ◽  
Donald E. Watenpaugh ◽  
Stuart M. C. Lee ◽  
...  
Keyword(s):  
Lower Body Negative Pressure ◽  
Bed Rest ◽  
Exercise Group ◽  
Erector Spinae ◽  
Paraspinal Muscle ◽  
Control Group ◽  
Cross Sectional ◽  
Before And After ◽  
Spine Function ◽  
Muscle Cross Sectional Area

Microgravity-induced lumbar paraspinal muscle deconditioning may contribute to back pain commonly experienced by astronauts and may increase the risk of postflight injury. We hypothesized that a combined resistive and aerobic exercise countermeasure protocol that included spinal loading would mitigate lumbar paraspinal muscle deconditioning during 60 days of bed rest in women. Sixteen women underwent 60-day, 6° head-down-tilt bed rest (BR) and were randomized into control and exercise groups. During bed rest the control group performed no exercise. The exercise group performed supine treadmill exercise within lower body negative pressure (LBNP) for 3-4 days/wk and flywheel resistive exercise for 2–3 days/wk. Paraspinal muscle cross-sectional area (CSA) was measured using a lumbar spine MRI sequence before and after BR. In addition, isokinetic spinal flexion and extension strengths were measured before and after BR. Data are presented as means ± SD. Total lumbar paraspinal muscle CSA decreased significantly more in controls (10.9 ± 3.4%) than in exercisers (4.3 ± 3.4%; P < 0.05). The erector spinae was the primary contributor (76%) to total lumbar paraspinal muscle loss. Moreover, exercise attenuated isokinetic spinal extension loss (−4.3 ± 4.5%), compared with controls (−16.6 ± 11.2%; P < 0.05). In conclusion, LBNP treadmill and flywheel resistive exercises during simulated microgravity mitigate decrements in lumbar paraspinal muscle structure and spine function. Therefore spaceflight exercise countermeasures that attempt to reproduce spinal loads experienced on Earth may mitigate spinal deconditioning during long-duration space travel.

scholarly journals LBNP exercise protects aerobic capacity and sprint speed of female twins during 30 days of bed rest

2009 ◽  
Vol 106 (3) ◽  
pp. 919-928 ◽  
Author(s):  
Stuart M. C. Lee ◽  
Suzanne M. Schneider ◽  
Wanda L. Boda ◽  
Donald E. Watenpaugh ◽  
Brandon R. Macias ◽  
...  
Keyword(s):  
Treadmill Exercise ◽  
Lower Body Negative Pressure ◽  
Bed Rest ◽  
Exercise Group ◽  
Peak Oxygen Consumption ◽  
Control Group ◽  
Treadmill Test ◽  
Sprint Speed ◽  
Long Duration ◽  
Volitional Fatigue

We have shown previously that treadmill exercise within lower body negative pressure (LBNPex) maintains upright exercise capacity (peak oxygen consumption, V̇o2peak) in men after 5, 15, and 30 days of bed rest (BR). We hypothesized that LBNPex protects treadmill V̇o2peak and sprint speed in women during a 30-day BR. Seven sets of female monozygous twins volunteered to participate. Within each twin set, one was randomly assigned to a control group (Con) and performed no countermeasures, and the other was assigned to an exercise group (Ex) and performed a 40-min interval (40–80% pre-BR V̇o2peak) LBNPex (51 ± 5 mmHg) protocol, plus 5 min of static LBNP, 6 days per week. Before and immediately after BR, subjects completed a 30.5-m sprint test and an upright graded treadmill test to volitional fatigue. These results in women were compared with previously reported reductions in V̇o2peak and sprint speed in male twins after BR. In women, sprint speed (−8 ± 2%) and V̇o2peak (−6 ± 2%) were not different after BR in the Ex group. In contrast, both sprint speed (−24 ± 5%) and V̇o2peak (−16 ± 3%) were significantly less after BR in the Con group. The effect of BR on sprint speed and V̇o2peak after BR was not different between women and men. We conclude that treadmill exercise within LBNP protects against BR-induced reductions in V̇o2peak and sprint speed in women and should prove effective during long-duration spaceflight.

WISE 2005: chronic bed rest impairs microcirculatory endothelium in women

2007 ◽  
Vol 293 (5) ◽  
pp. H3159-H3164 ◽  
Author(s):  
Claire Demiot ◽  
Françoise Dignat-George ◽  
Jacques-Olivier Fortrat ◽  
Florence Sabatier ◽  
Claude Gharib ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Lower Body Negative Pressure ◽  
Bed Rest ◽  
Endothelial Damage ◽  
Circulating Endothelial Cells ◽  
Control Group ◽  
Functional Evaluation ◽  
Specific Effects ◽  
Before And After ◽  
Endothelial Functions

Sedentary behavior has deleterious effects on the cardiovascular system, including reduced endothelial functions. A 2-mo bed rest study in healthy women [women international space simulation for exploration (WISE) 2005 program] presented a unique opportunity to analyze the specific effects of prolonged inactivity without other vascular risk factors on the endothelium. We investigated endothelial properties before and after 56 days of bed rest in 8 subjects who performed no exercise (control group: No-EX) and in 8 subjects who regularly performed treadmill exercise in a lower body negative pressure chamber as well as resistance exercise (countermeasure group, EX). A functional evaluation of the microcirculation in the skin was assessed with laser Doppler. We studied endothelium-dependent and -independent vasodilation using iontophoresis of acetylcholine and sodium nitroprusside, respectively. We also measured circulating endothelial cells (CECs), an index of endothelial damage. In the No-EX group, endothelium-dependent vasodilation was significantly reduced (35.4 ± 4.8% vs. 24.1 ± 3.8%, P < 0.05) by bed rest with a significant increase in the number of CECs (3.6 ± 1.4 vs. 10.6 ± 2.7 ml−1, P < 0.05). In the EX group, endothelium-dependent vasodilation and number of CECs were preserved. Our study shows that in humans prolonged bed rest causes impairment of endothelium-dependent function at the microcirculatory level, along with an increase in circulating endothelial cells. Microcirculatory endothelial dysfunction might participate in cardiovascular deconditioning, as well as in several bed rest-induced pathologies. We therefore conclude that the endothelium should be a target for countermeasures during periods of prolonged deconditioning.

scholarly journals Changes in intervertebral disc morphology persist 5 mo after 21-day bed rest

2011 ◽  
Vol 111 (5) ◽  
pp. 1304-1314 ◽  
Author(s):  
Daniel L. Belavý ◽  
P. Martin Bansmann ◽  
Gisela Böhme ◽  
Petra Frings-Meuthen ◽  
Martina Heer ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Signal Intensity ◽  
Muscle Activation ◽  
Bed Rest ◽  
Intervertebral Discs ◽  
Erector Spinae ◽  
Cross Sectional ◽  
Intensity Changes ◽  
Lumbar Muscle ◽  
Muscle Cross Sectional Area

As part of the nutrition-countermeasures (NUC) study in Cologne, Germany in 2010, seven healthy male subjects underwent 21 days of head-down tilt bed rest and returned 153 days later to undergo a second bout of 21-day bed rest. As part of this model, we aimed to examine the recovery of the lumbar intervertebral discs and muscle cross-sectional area (CSA) after bed rest using magnetic resonance imaging and conduct a pilot study on the effects of bed rest in lumbar muscle activation, as measured by signal intensity changes in T2-weighted images after a standardized isometric spinal extension loading task. The changes in intervertebral disc volume, anterior and posterior disc height, and intervertebral length seen after bed rest did not return to prebed-rest values 153 days later. While recovery of muscle CSA occurred after bed rest, increases ( P ≤ 0.016) in multifidus, psoas, and quadratus lumborum muscle CSA were seen 153 days after bed rest. A trend was seen for greater activation of the erector spinae and multifidus muscles in the standardized loading task after bed rest. Greater reductions of multifidus and psoas CSA muscle and greater increases in multifidus signal intensity with loading were associated with incidence of low back pain in the first 28 days after bed rest ( P ≤ 0.044). The current study contributes to our understanding of the recovery of the lumbar spine after 21-day bed rest, and the main finding was that a decrease in spinal extensor muscle CSA recovers within 5 mo after bed rest but that changes in the intervertebral discs persist.

scholarly journals Intermittent short-arm centrifugation is a partially effective countermeasure against upright balance deterioration following 60-day head-down tilt bed rest

2021 ◽  
Author(s):  
Enrico De Martino ◽  
Sauro Emerick Salomoni ◽  
Paul W. Hodges ◽  
Julie Hides ◽  
Kirsty Lindsay ◽  
...  
Keyword(s):  
Bed Rest ◽  
Standing Balance ◽  
Erector Spinae ◽  
Transversus Abdominis ◽  
Trunk Muscles ◽  
Control Group ◽  
Protective Effects ◽  
Gravitational Unloading ◽  
Frequency Power ◽  
Sway Frequency

This study investigated whether artificial gravity (AG), induced by short-radius centrifugation, mitigated deterioration in standing balance and anticipatory postural adjustments (APAs) of trunk muscles following 60-day head-down tilt bed rest. Twenty-four participants were allocated to one of three groups: control group (N=8); 30 minutes continuous AG daily (N=8); intermittent 6x5 minutes AG daily (N=8). Before and immediately after bed rest, standing balance was assessed in four conditions: eyes open and closed on both stable and foam surfaces. Measures including sway path, root-mean-square, and peak sway velocity, sway area, sway frequency power, and sway density curve were extracted from the centre of pressure displacement. APAs were assessed during rapid arm movements using intramuscular or surface electromyography electrodes of the rectus abdominis, obliquus externus and internus abdominis, transversus abdominis, erector spinae at L1, L2, L3, and L4 vertebral levels, and deep lumbar multifidus muscles. The relative latency between the EMG onset of the deltoid and each of the trunk muscles was calculated. All three groups had poorer balance performance in most of the parameters (all P<0.05) and delayed APAs of the trunk muscles following bed rest (all P<0.05). Sway path and sway velocity were deteriorated, and sway frequency power was less in those who received intermittent AG than in the control group (all P<0.05), particularly in conditions with reduced proprioceptive feedback. These data highlight the potential of intermittent AG to mitigate deterioration of some aspects of postural control induced by gravitational unloading, but no protective effects on trunk muscle responses were observed.

scholarly journals EFFECTS OF EXERCISE ON PHYSICAL FITNESS AND ANTHROPOMETRIC VARIABLES IN EX-CRACK COCAINE USERS

2017 ◽  
Vol 23 (4) ◽  
pp. 284-289
Author(s):  
Jéssica Abatti Martins ◽  
Ana Maria Volpato ◽  
Vanise dos Santos Ferreira Viero ◽  
Antonio Jose Grande ◽  
Leonardo Roever ◽  
...  
Keyword(s):  
Body Composition ◽  
Physical Fitness ◽  
Crack Cocaine ◽  
Controlled Trial ◽  
Exercise Group ◽  
Control Group ◽  
Beneficial Effects ◽  
Before And After ◽  
Cocaine Users ◽  
Total Body

ABSTRACT Introduction: Worldwide cocaine use in all its various forms is increasing; cocaine users exceeded 17 million in the world. In Brazil, this data is also alarming. A survey conducted in 2010 found that the country has more than 900,000 crack-cocaine users. Objective: To evaluate the effects of exercise on anthropometric variables and components of physical fitness in ex-crack cocaine users. Methods: Randomized controlled trial with 20 men, divided into exercise group (n=10) and control group (n=10), admitted to a detoxification center. We assessed the physical fitness components related to health (cardiorespiratory endurance, flexibility, muscular strength/endurance, and body composition) before and after the physical training program. Results: The exercise contributed to the maintenance of anthropometric variables, while the control group had an increased in total body fat and visceral fat. Regarding physical fitness, resistance training led to the increase of most variables studied, particularly strength and cardiorespiratory capacity. On the other hand, the VO2max and the strength of the sedentary subjects were reduced (P<0.05). Conclusion: The exercise showed beneficial effects on the components of physical fitness and maintenance of body composition.

Effects of aerobic plus explosive power exercises on bone remodeling and bone mineral density in young men

2017 ◽  
Vol 43 (1) ◽  
pp. 40-48
Author(s):  
Veysi Çay ◽  
Gurbuz Buyukyazi ◽  
Cevval Ulman ◽  
Fatma Taneli ◽  
Yeliz Doğru ◽  
...  
Keyword(s):  
Maximal Oxygen Consumption ◽  
Exercise Program ◽  
Exercise Group ◽  
Risk Level ◽  
Control Group ◽  
Maximal Heart Rate ◽  
Mineral Density ◽  
Explosive Power ◽  
Before And After ◽  
And Control

AbstractObjectives:This study aims to examine effects of aerobic jogging and explosive power exercises on body composition, maximal oxygen consumption (MaxVOMaterials and methods:Thirty seven healthy males were divided into exercise group (EG, n=19) and control group (CG, n=18). EG completed 10 weeks of outdoor aerobic (jogging at 60–70% maximal heart rate reserve starting from 20 min steadily increasing up to 28 min) and explosive power exercises (in 2–3 sets, with maximum repetitions lasting 15 s), 3 times per week. All measurements were taken before and after the exercise program. BMD was measured via dual energy X-ray absorptiometry (DEXA).Results:Body mass index (p<0.001) significantly decreased; MaxVOConclusion:Performing our outdoor exercise program in spring months might have an important role in the significant increase (9 vs. 22 ng/mL) in mean vitamin D level, which reached above the fracture risk level of 20 ng/mL.

scholarly journals The effect of 10-week swimming and bosu exercises on dynamic balance parameter in 8-10 years old boys

2019 ◽  
Vol 16 (3) ◽  
pp. 807-814
Author(s):  
Hilal Kılınç ◽  
Hacı Bayram Temur ◽  
Hacalet Mollaoğulları
Keyword(s):  
Dynamic Equilibrium ◽  
Dynamic Balance ◽  
Exercise Group ◽  
English Summary ◽  
Control Group ◽  
Swimming Training ◽  
Significant Difference ◽  
Before And After ◽  
Package Program ◽  
Post Test

Bu çalışma 8-10 yaş arası erkek çocuklarda yüzme egzersiz ve bosu çalışmalarının dinamik dengeye etkisini incelemek amacıyla yapıldı. Yaşları ortalaması 8,9333±,78492 yıl olan 30 katılımcı veli ve antrenörlerinden gönüllü katılımları ile ilgili aydınlanmış̧ onamları alınarak çalışmaya dahil edildi. Bunların 20' si egzersiz grubu diğer 10'u da kontrol grubudur. Egzersiz grubunun en az 1 yıl yüzme eğitimi almış olmalarına ve haftada 3 gün düzenli olarak yüzme antrenmanı yapıyor olmalarına dikkat edildi. Egzersiz grubu rastgele yöntemle 2 gruba ayrıldı. Birinci gruba yüzme ve bosu çalışmaları, ikinci gruba ise sadece yüzme egzersizleri yaptırıldı. Bu çalışma 10 hafta süreyle uygulandı. Katılımcıların antropometrik ölçümler ile dinamik denge ölçümleri planlanan antrenman programı öncesi ve sonrası olmak üzere iki defa alındı. Çalışma Van Olimpik yüzme havuzunda uygulandı. Verilerin analizinde SPSS 21 paket programı kullanıldı.  Analizler sonucunda yüzme eğitimi alan grubun A (Anterior), PM (Posteromedial) ve PL (Posterolateral) ön test - son test ölçüm  değerleri arasında anlamlı (p<0,01) fark olduğu saptandı. Yine yüzme ve bosu eğitimi alan grubun PM ve PL ön test - son test ölçüm  değerleri arasında anlamlı (p<0,01) fark olduğu belirlendi. Seçilmiş değişkenlerin ön test- son test ölçüm değerleri arasındaki farkların gruplar arasında anlamlı (p<0,05)  bir farklılığın olmadığı görüldü.   ​Extended English summary is in the end of Full Text PDF (TURKISH) file.   Özet This study was carried out to investigate the effect of swimming exercise and bosu studies on dynamic equilibrium in 8-10 years old boys. They were included in the study by taking their enlightened consent about their voluntary participation from 30 participants parents and coaches with an average age of 8,9333 ±, 78492 years. 20 of them were exercise group and 10 of them were control group. The exercise group had at least 1 year of swimming training and swimming training 3 days a week was paid attention to be doing regularly. The exercise group was randomly divided into two groups. The first group had swimming and bosu exercises and the second group had only swimming exercises. This study was performed for 10 weeks. The participants' anthropometric measurements and dynamic balance measurements were taken twice before and after the planned training program. The work was carried out at the Olympic swimming pool in Van. SPSS 21 package program was used to analyze the data. As a result of the analyzes, it was found that there was a significant difference (p<0.01) between the A (Anterior), PM (Poateromedial) and PL (Poaterolateral) pre-test and post-test measurements of the swimming group. It was determined that there was a significant difference (p <0.01) between the PM and PL pretest - posttest measurements of the group receiving swimming and bosu training. There was no significant difference (p <0.05) between the pre-test and post-test values ​​of the selected variables.

scholarly journals Effect of intermittent hypoxic training on orthostatic tolerance in humans before and after simulated microgravity

2020 ◽  
Author(s):  
VP Katuntsev ◽  
TV Sukhostavtseva ◽  
AN Kotov ◽  
MV Baranov
Keyword(s):  
Orthostatic Intolerance ◽  
Bed Rest ◽  
Daily Basis ◽  
Tilt Test ◽  
Control Group ◽  
Orthostatic Tolerance ◽  
Pronounced Increase ◽  
Intermittent Hypoxic Training ◽  
Hypoxic Training ◽  
Before And After

Reduced orthostatic tolerance (OT) is a serious concern facing space medicine. This work sought to evaluate the effects of intermittent hypoxic training (IHT) on OT in humans before and after 3 days of head-down bed rest (HDBR) used to model microgravity. The study was carried out in 16 male volunteers aged 18 to 40 years and included 2 series of experiments with 11-day and 21-day IHT administered on a daily basis. During the first IHT session, the concentration of oxygen in the inspired gas mixture was 10%; for other sessions it was adjusted to 9%. OT was assessed by a 20-minute-long orthostatic tilt test (OTT) conducted before and after HDBR. Before HDBR, orthostatic intolerance was observed in 3 participants, while after HDBR, it was observed in 9 of 16 volunteers (p < 0.05). During OTT conducted after HDBR, the heart rate (HR) exceeded control values by 26.8% (p < 0.01). Preexposure to any of the applied IHT regimens led to a reduction in the number of volunteers with orthostatic intolerance. After the 11-day IHT program, there was a less pronounced increase in HR during OTT before HDBR; with the extended IHT regimen, less pronounced changes were observed for HR, systolic, diastolic and mean blood pressure (BP). The increase in HR during OTT after HDBR was significantly lower in the group that had completed the 11-day IHT program, while BP remained stable. The changes in HR and systolic BP were less pronounced in the group that had completed the 21-day IHT program than in the control group (p < 0.05). Thus, IHT reduced the risk of orthostatic disorders and mitigated changes in cardiovascular parameters during the orthostatic test.

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