scholarly journals Paper-Based Disk-Type Self-Powered Glucose Biosensor Based on Screen-Printed Biofuel Cell Array

2019 ◽  
Vol 166 (12) ◽  
pp. B1063-B1068 ◽  
Author(s):  
Isao Shitanda ◽  
Yuki Fujimura ◽  
Saki Nohara ◽  
Yoshinao Hoshi ◽  
Masayuki Itagaki ◽  
...  
Energies ◽  
2019 ◽  
Vol 12 (5) ◽  
pp. 825 ◽  
Author(s):  
Gymama Slaughter ◽  
Tanmay Kulkarni

This work presents the characterization of a self-powered glucose biosensor using individual sequential assays of human plasma glucose obtained from diabetic patients. The self-powered glucose biosensor is exploited to optimize the assay parameters for sensing plasma glucose levels. In particular, the biofuel cell component of the system at pH 7.4, 37 °C generates a power density directly proportional to plasma glucose and exhibited a maximum power density of 0.462 mW·cm−2 at a cell voltage of 0.213 V in 5 mM plasma glucose. Plasma glucose is further sensed by monitoring the charge/discharge frequency (Hz) of the integrated capacitor functioning as the transducer. With this method, the plasma glucose is quantitatively detected in 100 microliters of human plasma with unprecedented sensitivity, as high as 104.51 ± 0.7 Hz·mM−1·cm−2 and a detection limit of 2.31 ± 0.3 mM. The results suggest the possibility to sense human plasma glucose at clinically relevant concentrations without the use of an external power source.


Biosensors ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 16
Author(s):  
Kantapat Chansaenpak ◽  
Anyanee Kamkaew ◽  
Sireerat Lisnund ◽  
Pannaporn Prachai ◽  
Patipat Ratwirunkit ◽  
...  

Biofuel cells allow for constructing sensors that leverage the specificity of enzymes without the need for an external power source. In this work, we design a self-powered glucose sensor based on a biofuel cell. The redox enzymes glucose dehydrogenase (NAD-GDH), glucose oxidase (GOx), and horseradish peroxidase (HRP) were immobilized as biocatalysts on the electrodes, which were previously engineered using carbon nanostructures, including multi-wall carbon nanotubes (MWCNTs) and reduced graphene oxide (rGO). Additional polymers were also introduced to improve biocatalyst immobilization. The reported design offers three main advantages: (i) by using glucose as the substrate for the both anode and cathode, a more compact and robust design is enabled, (ii) the system operates under air-saturating conditions, with no need for gas purge, and (iii) the combination of carbon nanostructures and a multi-enzyme cascade maximizes the sensitivity of the biosensor. Our design allows the reliable detection of glucose in the range of 0.1–7.0 mM, which is perfectly suited for common biofluids and industrial food samples.


Nano Research ◽  
2020 ◽  
Vol 14 (3) ◽  
pp. 707-714
Author(s):  
Shuai Hao ◽  
He Zhang ◽  
Xiaoxuan Sun ◽  
Junfeng Zhai ◽  
Shaojun Dong

2018 ◽  
Vol 54 (46) ◽  
pp. 5823-5826 ◽  
Author(s):  
Xinxin Xiao ◽  
Edmond Magner

A quasi-solid-state and flexible biofuel cell using a hydrogel electrolyte preloaded with sugar as a fuel is described.


Biosensors ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 114 ◽  
Author(s):  
Brandon G. Roy ◽  
Julia L. Rutherford ◽  
Anna E. Weaver ◽  
Kevin Beaver ◽  
Michelle Rasmussen

Glutathione is an important biological molecule which can be an indicator of numerous diseases. A method for self-powered detection of glutathione levels in solution has been developed using an enzymatic biofuel cell. The device consists of a glucose oxidase anode and a bilirubin oxidase cathode. For the detection of glutathione, the inhibition of bilirubin oxidase leads to a measurable decrease in current and power output. The reported method has a detection limit of 0.043 mM and a linear range up to 1.7 mM. Being able to detect a range of concentrations can be useful in evaluating a patient’s health. This method has the potential to be implemented as a quick, low-cost alternative to previously reported methods.


2018 ◽  
Vol 102 ◽  
pp. 383-388 ◽  
Author(s):  
Dominika Majdecka ◽  
Sylwia Draminska ◽  
Dariusz Janusek ◽  
Paweł Krysinski ◽  
Renata Bilewicz
Keyword(s):  

2014 ◽  
Vol 1 (11) ◽  
pp. 1854-1858 ◽  
Author(s):  
Felipe Conzuelo ◽  
Jeevanthi Vivekananthan ◽  
Sascha Pöller ◽  
José M. Pingarrón ◽  
Wolfgang Schuhmann

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