Development and Evaluation of Prussian Blue Mediated Glucose Sensor for Reverse Iontophoresis Application

2015 ◽  
Vol 4 (11) ◽  
pp. B13-B16 ◽  
Author(s):  
E. K. Varadharaj ◽  
N. Jampana
2005 ◽  
Vol 17 (3) ◽  
pp. 210-222 ◽  
Author(s):  
Annamalai?Senthil Kumar ◽  
Pei-Yen Chen ◽  
Shu-Hua Chien ◽  
Jyh-Myng Zen

2013 ◽  
Vol 641-642 ◽  
pp. 785-788 ◽  
Author(s):  
Hong Wang ◽  
Yang Yang Liu ◽  
Xiao Jing Yao ◽  
Yan Li ◽  
Ji Yu Wu ◽  
...  

Objective: Making a glucose sensor to detect the glucose which is extracted from the tissue fluid on reverse iontophoresis. Method: In the role of the catalysis of glucose oxidase which was fixed in polyethylene oxide gel, the glucose and potassium ferricyanide were change into gluconic acid and potassium ferrocyanide. Then we could get the concentration of glucose by detecting the current which was created by the redox reaction. Results: The glucose sensors could detect the concentration of glucose in the range of 2.2~22mmol/l and have a good linear too. The conformance test results show that the deviation of multiple measurements of the same sensor is less than 2% and the reaction time is less than 1s. Conclusion: The sensors could detect the blood glucose.


2008 ◽  
Vol 8 (9) ◽  
pp. 4543-4547 ◽  
Author(s):  
Dong-Yun Lee ◽  
A. K. M. Kafi ◽  
Won-Suk Choi ◽  
Sang-Hyun Park ◽  
Young-Soo Kwon

The structure and dynamic organization of a mixed Langmuir film of glucose oxidase (GOx) and lipid at the air–water interface were studied. The film was transferred onto the Prussian Blue (PB)-modified Pt electrode for biosensor preparation. The PB modified electrode showed well defined redox peaks in 0.1 M PBS electrolyte. The Langmuir film was characterized at the air–water interface by π-A isotherms. The mixed monolayer was formed by spreading GOx on the LB trough covered with lipid. Time-pressure results show that at least 90 minutes are required to reach the equilibrium state of GOx-lipid film. The monolayer was transferred onto the PB-modified electrode when surface pressure was 40 mN/m. This sensor was characterized by a very low detection limit and a wide linear range. The optimal conditions for both fabricating and response of the sensor were investigated. The proposed biosensor showed a linear calibration range from 5 × 10−6 to 6 × 10−5 M. The detection limit was determined to be 1.5 × 10−6 M.


RSC Advances ◽  
2019 ◽  
Vol 9 (40) ◽  
pp. 22790-22794 ◽  
Author(s):  
Kyu Oh Kim ◽  
Geon Jin Kim ◽  
Ji Hye Kim

In this study, we aimed to develop a cellulose/β-cyclodextrin (β-CD) electrospun immobilized GOx enzyme patch with reverse iontophoresis for noninvasive monitoring of interstitial fluid (ISF) glucose levels (0.1–0.6 mM dm−3).


Sensors ◽  
2002 ◽  
Vol 2 (4) ◽  
pp. 127-136 ◽  
Author(s):  
Jianzhong Zhu ◽  
Ziqiang Zhu ◽  
Zongsheng Lai ◽  
Rong Wang ◽  
Xiaoming Guo ◽  
...  

2021 ◽  
Author(s):  
Anjali Chaudhary ◽  
Tanushree Ghosh ◽  
Devesh K Pathak ◽  
Suchita Kandpal ◽  
Manushree Tanwar ◽  
...  
Keyword(s):  

Author(s):  
Lorna K. Mayo ◽  
Kenneth C. Moore ◽  
Mark A. Arnold

An implantable artificial endocrine pancreas consisting of a glucose sensor and a closed-loop insulin delivery system could potentially replace the need for glucose self-monitoring and regulation among insulin dependent diabetics. Achieving such a break through largely depends on the development of an appropriate, biocompatible membrane for the sensor. Biocompatibility is crucial since changes in the glucose sensors membrane resulting from attack by orinter action with living tissues can interfere with sensor reliability and accuracy. If such interactions can be understood, however, compensations can be made for their effects. Current polymer technology offers several possible membranes that meet the unique chemical dynamics required of a glucose sensor. Two of the most promising polymer membranes are polytetrafluoroethylene (PTFE) and silicone (Si). Low-voltage scanning electron microscopy, which is an excellent technique for characterizing a variety of polymeric and non-conducting materials, 27 was applied to the examination of experimental sensor membranes.


2006 ◽  
Vol 12 ◽  
pp. 7
Author(s):  
Lois G. Jovanovic ◽  
Howard Zisser ◽  
Timothy Bailey ◽  
Roy Kaplan ◽  
Satish Garg
Keyword(s):  

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