Effect of Polarization on Platinum Deposition at LSM/YSZ Interfaces

2019 ◽  
Vol 35 (1) ◽  
pp. 2213-2216 ◽  
Author(s):  
Katsuhiko Yamaji ◽  
Taro Shimonosono ◽  
Haruo Kishimoto ◽  
Manuel E. Brito ◽  
Teruhisa Horita ◽  
...  
Keyword(s):  
Platinum Deposition

Arsenic and platinum deposition during cathodic hydrogenation

1983 ◽  
Vol 17 (3) ◽  
pp. 365-369 ◽  
Author(s):  
M.B. Lewis ◽  
K. Farrell
Keyword(s):  
Platinum Deposition

A DNA hybridization sensor based on catalytic response by platinum deposition

The Analyst ◽  
2015 ◽  
Vol 140 (4) ◽  
pp. 1014-1018 ◽  
Author(s):  
Tomoyuki Yasukawa ◽  
Yuya Yamashita ◽  
Riku Moede ◽  
Daichi Nakayama ◽  
Seiichiro Iijima ◽  
...  
Keyword(s):  
Dna Hybridization ◽  
Catalytic Reduction ◽  
Electrochemical System ◽  
Specific Sequence ◽  
Platinum Deposition

A novel electrochemical system based on the catalytic reduction of protons with deposited platinum is proposed for the sensing of DNA with a specific sequence.

Microscopic Investigation of Platinum Deposition in PEMFC Cross-Sections Using AFM and SEM

2013 ◽  
Vol 160 (6) ◽  
pp. F687-F697 ◽  
Author(s):  
Stefan Helmly ◽  
Renate Hiesgen ◽  
Tobias Morawietz ◽  
Xiao-Zi Yuan ◽  
Haijiang Wang ◽  
...  
Keyword(s):  
Cross Sections ◽  
Microscopic Investigation ◽  
Platinum Deposition

Platinum deposition in skin as a possible mechanism for peripheral sensory neuropathy (PSN) in patients (pts) with colorectal cancer (CRC) following oxaliplatin-based therapy.

2018 ◽  
Vol 36 (4_suppl) ◽  
pp. 685-685 ◽  
Author(s):  
Yanshuo Cao ◽  
Qing Chang ◽  
Wenjiang Zhang ◽  
Olga Ornatsky ◽  
Eric Xueyu Chen
Keyword(s):  
Cumulative Dose ◽  
High Performance ◽  
Sensory Neuropathy ◽  
Symptom Assessment ◽  
Platinum Deposition ◽  
Treatment Information ◽  
Sensory Score ◽  
Formalin Fixed Paraffin Embedded ◽  
Skin Biopsies ◽  
Eortc Qlq

685 Background: Oxaliplatin plus fluorouracil (FOLFOX) is a standard treatment for CRC pts. One of the most common and dose-limiting side effects of oxaliplatin is PSN. The mechanism of this phenomenon is poorly understood. Previous studies suggested that higher serum platinum levels were related to more severe neuropathy in testicular cancer pts. Methods: CRC pts who completed adjuvant FOLFOX at least 6 months prior to enrollment are eligible. Baseline demographic and treatment information were collected. EORTC CIPN20 (with EORTC QLQ-C30) questionnaire was used for self-reported PSN symptom assessment. Peripheral blood samples were collected for total/free platinum concentrations using high-performance liquid chromatography with tandem mass spectrometry (HPLC/MS-MS). Skin biopsies were obtained from the lower leg of consented pts. Imaging mass cytometry (IMC) was used to visualize platinum deposition (195Pt) and intra-epidermal nerve fiber (IENF) (PGP9.5-154Sm) in formalin-fixed paraffin embedded (FFPE) skin biopsy samples stained with a metal-conjugated antibody cocktail. Results: Nine patients were enrolled. Median age was 51.8 yr (range: 34.5-69.4 yr); male/ female: 5/4; mean cumulative dose of oxaliplatin was 800.7 ± 188.2 mg/m2; median time from last dose of oxaliplatin to enrollment was 48 months (range: 7.2-65.6 months). The mean sensory score from CIPN20 was 15.4 ± 4.3 (range: 10-25). Platinum was undetectable in plasma samples collected from all 9 patients. In skin samples, IMC showed significant platinum depositions and IENF. Conclusions: Severity of PSN was not related to cumulative dose of oxaliplatin or interval from last dose of oxaliplatin. Although platinum was undetectable in plasma in these patients, platinum was readily detectable in skin biopsies up to 65.6 months post completion of FOLFOX. This is the first demonstration of platinum deposition in skin post oxaliplatin treatment and it provides a possible mechanism for oxaliplatin-induced PSN.

ChemInform Abstract: Advanced Electrodes for Solid Acid Fuel Cells by Platinum Deposition on CsH2PO4.

ChemInform ◽  
2011 ◽  
Vol 42 (25) ◽  
pp. no-no
Author(s):  
Alexander B. Papandrew ◽  
Calum R. I. Chisholm ◽  
Ramez A. Elgammal ◽  
Mustafa M. Oezer ◽  
Strahinja K. Zecevic
Keyword(s):  
Fuel Cells ◽  
Solid Acid ◽  
Platinum Deposition
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