scholarly journals 5D Flow MRI: A Fully Self-gated, Free-running Framework for Cardiac and Respiratory Motion–resolved 3D Hemodynamics

2020 ◽  
Vol 2 (6) ◽  
pp. e200219
Author(s):  
Liliana E. Ma ◽  
Jérôme Yerly ◽  
Davide Piccini ◽  
Lorenzo Di Sopra ◽  
Christopher W. Roy ◽  
...  
2021 ◽  
Vol 3 (3) ◽  
pp. e219001
Author(s):  
Liliana E. Ma ◽  
Jérôme Yerly ◽  
Davide Piccini ◽  
Lorenzo Di Sopra ◽  
Christopher W. Roy ◽  
...  

Author(s):  
Mariana B. L. Falcão ◽  
Lorenzo Di Sopra ◽  
Liliana Ma ◽  
Mario Bacher ◽  
Jérôme Yerly ◽  
...  
Keyword(s):  
Flow Mri ◽  

2017 ◽  
Vol 78 (5) ◽  
pp. 1877-1882 ◽  
Author(s):  
Petter Dyverfeldt ◽  
Tino Ebbers

2019 ◽  
Vol 82 (6) ◽  
pp. 2118-2132 ◽  
Author(s):  
Lorenzo Di Sopra ◽  
Davide Piccini ◽  
Simone Coppo ◽  
Matthias Stuber ◽  
Jérôme Yerly

Author(s):  
Carmen P. S. Blanken ◽  
Eric M. Schrauben ◽  
Eva S. Peper ◽  
Lukas M. Gottwald ◽  
Bram F. Coolen ◽  
...  

Magnetic resonance imaging (MRI) can potentially be used for non-invasive screening of patients with stable angina pectoris to identify probable obstructive coronary artery disease. MRI-based coronary blood flow quantification has to date only been performed in a 2D fashion, limiting its clinical applicability. In this study, we propose a framework for coronary blood flow quantification using accelerated 4D flow MRI with respiratory motion correction and compressed sensing image reconstruction. We investigate its feasibility and repeatability in healthy subjects at rest. Fourteen healthy subjects received 8 times-accelerated 4D flow MRI covering the left coronary artery (LCA) with an isotropic spatial resolution of 1.0 mm3. Respiratory motion correction was performed based on 1) lung-liver navigator signal, 2) real-time monitoring of foot-head motion of the liver and LCA by a separate acquisition, and 3) rigid image registration to correct for anterior-posterior motion. Time-averaged diastolic LCA flow was determined, as well as time-averaged diastolic maximal velocity (VMAX) and diastolic peak velocity (VPEAK). 2D flow MRI scans of the LCA were acquired for reference. Scan-rescan repeatability and agreement between 4D flow MRI and 2D flow MRI were assessed in terms of concordance correlation coefficient (CCC) and coefficient of variation (CV). The protocol resulted in good visibility of the LCA in 11 out of 14 subjects (six female, five male, aged 28 ± 4 years). The other 3 subjects were excluded from analysis. Time-averaged diastolic LCA flow measured by 4D flow MRI was 1.30 ± 0.39 ml/s and demonstrated good scan-rescan repeatability (CCC/CV = 0.79/20.4%). Time-averaged diastolic VMAX (17.2 ± 3.0 cm/s) and diastolic VPEAK (24.4 ± 6.5 cm/s) demonstrated moderate repeatability (CCC/CV = 0.52/19.0% and 0.68/23.0%, respectively). 4D flow- and 2D flow-based diastolic LCA flow agreed well (CCC/CV = 0.75/20.1%). Agreement between 4D flow MRI and 2D flow MRI was moderate for both diastolic VMAX and VPEAK (CCC/CV = 0.68/20.3% and 0.53/27.0%, respectively). In conclusion, the proposed framework of accelerated 4D flow MRI equipped with respiratory motion correction and compressed sensing image reconstruction enables repeatable diastolic LCA flow quantification that agrees well with 2D flow MRI.


2020 ◽  
Vol 32 (1) ◽  
pp. 35
Author(s):  
Pietro Sergio ◽  
Antonio Miceli
Keyword(s):  
4D Flow ◽  

2001 ◽  
Vol 44 (2) ◽  
pp. 201 ◽  
Author(s):  
Su Young Park ◽  
Hi Jin Park ◽  
Hong Kim ◽  
Hee Jung Lee ◽  
Sung Ku Woo ◽  
...  
Keyword(s):  

2013 ◽  
Vol E96.C (2) ◽  
pp. 241-244
Author(s):  
Ryuta YAMANAKA ◽  
Taka FUJITA ◽  
Hideyuki SOTOBAYASHI ◽  
Atsushi KANNO ◽  
Tetsuya KAWANISHI

Author(s):  
O. Breitenstein ◽  
J.P. Rakotoniaina ◽  
F. Altmann ◽  
J. Schulz ◽  
G. Linse

Abstract In this paper new thermographic techniques with significant improved temperature and/or spatial resolution are presented and compared with existing techniques. In infrared (IR) lock-in thermography heat sources in an electronic device are periodically activated electrically, and the surface is imaged by a free-running IR camera. By computer processing and averaging the images over a certain acquisition time, a surface temperature modulation below 100 µK can be resolved. Moreover, the effective spatial resolution is considerably improved compared to stead-state thermal imaging techniques, since the lateral heat diffusion is suppressed in this a.c. technique. However, a serious limitation is that the spatial resolution is limited to about 5 microns due to the IR wavelength range of 3 -5 µm used by the IR camera. Nevertheless, we demonstrate that lock-in thermography reliably allows the detection of defects in ICs if their power exceeds some 10 µW. The imaging can be performed also through the silicon substrate from the backside of the chip. Also the well-known fluorescent microthermal imaging (FMI) technique can be be used in lock-in mode, leading to a temperature resolution in the mK range, but a spatial resolution below 1 micron.


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