scholarly journals Imaging of Small Bowel Disease: Comparison of Capsule Endoscopy, Standard Endoscopy, Barium Examination, and CT

Radiographics ◽  
2005 ◽  
Vol 25 (3) ◽  
pp. 697-711 ◽  
Author(s):  
Amy K. Hara ◽  
Jonathan A. Leighton ◽  
Virender K. Sharma ◽  
Russell I. Heigh ◽  
David E. Fleischer
Keyword(s):  
Small Bowel ◽  
Capsule Endoscopy ◽  
Bowel Disease ◽  
Small Bowel Disease ◽  
Barium Examination

M2A Wireless Capsule Endoscopy Versus Enteroclysis; A Prospective Study in 68 Patients with Suspected Small Bowel Disease

2004 ◽  
Vol 59 (5) ◽  
pp. P147 ◽  
Author(s):  
Periklis Apostolopoulos ◽  
Eleftheria Giannakoulopoulou ◽  
Ioannis S. Papanikolaou ◽  
Georgios Alexandrakis ◽  
X. Papacharalampous ◽  
...  
Keyword(s):  
Small Bowel ◽  
Prospective Study ◽  
Capsule Endoscopy ◽  
Bowel Disease ◽  
Wireless Capsule Endoscopy ◽  
Small Bowel Disease ◽  
A Prospective Study ◽  
Wireless Capsule

Comparison of detectability of small-bowel lesions between capsule endoscopy and double-balloon endoscopy for patients with suspected small-bowel disease

2009 ◽  
Vol 69 (4) ◽  
pp. 857-865 ◽  
Author(s):  
Akira Fukumoto ◽  
Shinji Tanaka ◽  
Takayoshi Shishido ◽  
Yoshito Takemura ◽  
Shiro Oka ◽  
...  
Keyword(s):  
Small Bowel ◽  
Capsule Endoscopy ◽  
Bowel Disease ◽  
Small Bowel Disease ◽  
Double Balloon Endoscopy ◽  
Double Balloon

scholarly journals Video capsule endoscopy: Initial experience from a tertiary care center in Sri Lanka

2021 ◽  
Vol 12 (11) ◽  
pp. 40-44
Author(s):  
Dinesh Rangika Perera ◽  
Piyal Rangana ◽  
Sanjeewa Aryasingha
Keyword(s):  
Small Bowel ◽  
Sri Lanka ◽  
Capsule Endoscopy ◽  
Bowel Disease ◽  
Diagnostic Yield ◽  
Tertiary Care ◽  
Small Bowel Disease ◽  
Small Intestinal ◽  
Intestinal Ulcers ◽  
Small Bowel Bleeding

Background: Since its global introduction in 2000, capsule endoscopy (CE) has revolutionized the evaluation of small bowel disease. Aims and Objective: The aim of this study was to share our experience with CE including the findings and its diagnostic yield. Materials and Methods: A retrospective study was carried out at Colombo South Teaching Hospital of Sri Lanka. Data of patients who underwent CE from its initiation in 2017 until June 2020 were obtained from the hospital computer database. These included the patient demographics, indications for the study, quality of bowel preparation, and its findings. Results: The study included 54 patients with a mean age of 55 years. Mean gastric time and small bowel transit time were 52 and 272 min, respectively. Forty-five CE studies were done for the evaluation of small bowel bleeding and an abnormal study was found in 26 (57.78%) patients. Small intestinal ulcers and erosions were the most frequently found abnormality (n=16, 35.56%) followed by tumors (n=5, 11.11%). Active bleeding was evident in 14 (31.11%) patients. Overall diagnostic yield was higher in those with a history of overt bleeding (n=15, 71.43%) compared to occult bleeding (n=11, 45.83%). Most patients who were evaluated for abdominal pain and diarrhea had normal CE except for two who had small intestinal ulcers and subepithelial lesions. Only one case was complicated with capsule retention. Conclusion: CE is a useful investigation for the evaluation of small bowel disease, particularly in suspected small bowel bleeding. In contrast to western population, ulcers and erosions were the more frequently found abnormalities seen in local setting.

scholarly journals Panenteric capsule endoscopy identifies proximal small bowel disease guiding upstaging and treatment intensification in Crohn’s disease: A European multicentre observational cohort study

2020 ◽  
pp. 205064062094866 ◽  
Author(s):  
Foong Way D Tai ◽  
Pierre Ellul ◽  
Alfonso Elosua ◽  
Ignacio Fernandez-Urien ◽  
Gian E Tontini ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Capsule Endoscopy ◽  
Bowel Disease ◽  
Mucosal Healing ◽  
Small Bowel Disease ◽  
Treatment Intensification ◽  
Non Invasive ◽  
Proximal Small Bowel

Background Endoscopically defined mucosal healing in Crohn’s disease is associated with improved outcomes. Panenteric capsule endoscopy enables a single non-invasive assessment of small and large bowel mucosal inflammation. Aims and methods: This multicentre observational study of patients with suspected and established Crohn’s disease examined the feasibility, safety and impact on patient outcomes of panenteric capsule endoscopy in routine clinical practice. The potential role in assessment of disease severity and extent by a comparison with existing clinical and biochemical markers is examined. Results Panenteric capsule endoscopy was performed on 93 patients (71 with established and 22 with suspected Crohn’s disease). A complete examination occurred in 85% (79/93). Two cases (2.8%) of capsule retention occurred in patients with established Crohn’s disease. Panenteric capsule resulted in management change in 38.7% (36/93) patients, including 64.6% (32/48) of those with an established diagnosis whose disease was active, and all three patients with newly diagnosed Crohn’s disease. Montreal classification was upstaged in 33.8% of patients with established Crohn’s disease and mucosal healing was demonstrated in 15.5%. Proximal small bowel disease upstaged disease in 12.7% and predicted escalation of therapy (odds ratio 40.3, 95% confidence interval 3.6–450.2). Raised C-reactive protein and faecal calprotectin were poorly sensitive in detecting active disease (0.48 and 0.59 respectively). Conclusions Panenteric capsule endoscopy was feasible in routine practice and the ability to detect proximal small bowel disease may allow better estimation of prognosis and guide treatment intensification. Panenteric capsule endoscopy may be a suitable non-invasive endoscopic investigation in determining disease activity and supporting management decisions.

P116 SMALL BOWEL INVOLVEMENT IN CHRONIC GRANULOMATOUS DISEASE COLITIS

2020 ◽  
Vol 26 (Supplement_1) ◽  
pp. S19-S19
Author(s):  
Sumona Bhattacharya ◽  
Sonia Taneja ◽  
Christa Zerbe ◽  
Suk See DeRavin ◽  
Harry Malech ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Crohn’S Disease ◽  
Abdominal Pain ◽  
Small Bowel ◽  
Chronic Granulomatous Disease ◽  
Capsule Endoscopy ◽  
Bowel Disease ◽  
Granulomatous Disease ◽  
Small Bowel Disease ◽  
Bowel Involvement

Abstract Chronic granulomatous disease (CGD) is a rare disorder caused by genetic mutations of the nicotinamide adenine dinucleotide phosphate oxidase complex (NADPH), occurring in approximately 1/200,000 individuals. These mutations decrease residual reactive oxygen species (ROS) levels, leading to dysregulated inflammation. Inflammatory manifestations can be widespread, including severe and recurrent infections. The gastrointestinal tract is the most commonly affected organ with resultant inflammatory bowel disease, termed CGD colitis. Manifestations include abdominal pain, diarrhea with or without blood, nausea/vomiting, obstructions, and fistulas which can occur in a perianal distribution. Patients are often misdiagnosed with Crohn’s disease or ulcerative colitis, especially in the absence of extensive infectious history. We aimed to characterize the small bowel involvement in CGD. Data is presented from a combined retrospective and ongoing prospective observational study of patients with genetically-confirmed CGD who underwent wireless video capsule endoscopy (VCE) at the National Institutes of Health Clinical Center (n = 8). VCEs were performed for clinical indications including abdominal pain (88%), diarrhea (75%), bloody stools (38%), and/or nausea/vomiting (25%). One patient (13%) underwent VCE for otherwise unexplained high inflammatory markers. Laboratory evaluation was significant for leukopenia/leukocytosis (75%), anemia (63%), and elevated C reactive-protein levels (63%). Seven patients (88%) had prior small bowel imaging, however none showed evidence of any abnormality in this organ. The most common VCE findings were ulcers and/or erosions (88%). Most patients also displayed other mucosal changes consistent with inflammation such as erythema and/or edema (88%). There was also evidence of blood or hematin on 63% of the endoscopies. While therapies for CGD colitis are targeted towards colonic involvement, our findings show that the vast majority of symptomatic patients also have active small bowel disease including ulcers, erosions, evidence of bleeding, and other signs of inflammation. These findings, however, are not specific to CGD. Given that certain biologic medications used for Crohn’s disease and ulcerative colitis have been shown to increase the risk of life-threatening infections in patients with CGD, it is important to keep other forms of IBD, especially CGD-related IBD, in mind when interpreting small bowel capsule endoscopy in patients with suspected IBD. Lastly, in patients with confirmed CGD colitis, small bowel disease should be rigorously investigated, and therapy should also seek to address small bowel involvement. Of note, our patients did not display any radiographic abnormalities of the small bowel. Due to our small sample size, we aim to study additional patients in the future to augment our data.

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