Comparison of Techniques for Image-guided Ablation of Focal Liver Tumors

Radiology ◽  
2002 ◽  
Vol 223 (2) ◽  
pp. 304-307 ◽  
Author(s):  
S. Nahum Goldberg
Keyword(s):  
Liver Tumors ◽  
Image Guided ◽  
Comparison Of Techniques

SLIR: Synthesis, localization, inpainting, and registration for image-guided thermal ablation of liver tumors

2020 ◽  
Vol 65 ◽  
pp. 101763 ◽  
Author(s):  
Dongming Wei ◽  
Sahar Ahmad ◽  
Jiayu Huo ◽  
Pu Huang ◽  
Pew-Thian Yap ◽  
...  
Keyword(s):  
Thermal Ablation ◽  
Liver Tumors ◽  
Image Guided

Transarterial Fiducial Marker Placement for Image-guided Proton Therapy for Malignant Liver Tumors

2014 ◽  
Vol 38 (5) ◽  
pp. 1288-1293 ◽  
Author(s):  
Kengo Ohta ◽  
Masashi Shimohira ◽  
Shigeru Sasaki ◽  
Hiromitsu Iwata ◽  
Hiroko Nishikawa ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Liver Tumors ◽  
Fiducial Marker ◽  
Image Guided ◽  
Malignant Liver Tumors ◽  
Malignant Liver

Development of radiotherapeutic rhenium-188 liposomes in alginate microspheres (Rhe-LAMs) for treatment of liver tumors and technetium-99m liposomes in alginate microspheres (Tech-LAMs) for image-guided treatment planning.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e15599-e15599
Author(s):  
Ryan D. Bitar ◽  
Jorge Lopera ◽  
Ande Bao ◽  
Jaclyn Merlo ◽  
Francisco Cigarroa ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Treatment Planning ◽  
Liver Tumors ◽  
Effective Means ◽  
Nuclear Imaging ◽  
Technetium 99M ◽  
Image Guided ◽  
Imaging Results ◽  
Radioactivity Retention

e15599 Background: Radio-embolic agents such as beta-emitting yttrium-90 spheres have been widely adopted as a modality for liver cancer therapy; however, their production can be timely and costly, shunting to the lungs may occur, and post-procedural visualization is limited. Alginate, a polysaccharide which can easily be formed into microspheres, has already been investigated for drug delivery applications; however, we propose utilizing alginate to manufacture radioembolic microspheres for intra-arterial delivery to liver tumors: Rhenium-188/186-labeled liposomes in alginate microspheres (Rhe-LAMS) as a radioembolic agent for the treatment of liver tumors and technetium-99m labeled liposomes in alginate microspheres (Tech-LAMs) as an agent for nuclear image-guided pre-treatment planning for liver cancer patients. Methods: Liposomes were manufactured and labeled with either Re-188/186 or Tc-99m. The liposomes were then mixed with alginate solution and then cross-linked with CaCl2 to form microspheres. Microsphere diameter was evaluated via light microscopy, and retention of radioactivity was measured over time via dosimeter. Microspheres containing free Re-186/Tc-99m (i.e. no liposomes) were also constructed for control comparison. To test in vivo stability, Tech-LAMs were intra-arterially injected into the liver of rabbits for nuclear imaging. Results: 2 ml batches of Rhe-LAMS/Tech-LAMS of 20-80 microns could be manufactured in 3 hours. Radiolabeling efficiency of the liposomes reached 85% and retention of radioactivity in microspheres reached 75%. After overnight incubation, 90% activity was retained. Control microspheres showed a retention of < 5%. In vivo imaging revealed absent activity in the lungs and high embolic activity in the liver. Conclusions: Our novel method demonstrated success regarding radioactivity retention and embolization capabilities. We envision this method to be a quickly-producible, cost-efficient, and effective means for radioembolization of liver tumors that could be adopted by any radiopharmacy.

scholarly journals Stereotactic Image-Guided Microwave Ablation for Malignant Liver Tumors—A Multivariable Accuracy and Efficacy Analysis

2020 ◽  
Vol 10 ◽  
Author(s):  
Pascale Tinguely ◽  
Lorenz Frehner ◽  
Anja Lachenmayer ◽  
Vanessa Banz ◽  
Stefan Weber ◽  
...  
Keyword(s):  
Microwave Ablation ◽  
Liver Tumors ◽  
Efficacy Analysis ◽  
Image Guided ◽  
Malignant Liver Tumors ◽  
Malignant Liver

Target Coverage in Image-Guided Stereotactic Body Radiotherapy of Liver Tumors

2007 ◽  
Vol 68 (1) ◽  
pp. 282-290 ◽  
Author(s):  
Wouter Wunderink ◽  
Alejandra Méndez Romero ◽  
Eliana M. Vásquez Osorio ◽  
Hans C.J. de Boer ◽  
René P. Brandwijk ◽  
...  
Keyword(s):  
Stereotactic Body Radiotherapy ◽  
Liver Tumors ◽  
Target Coverage ◽  
Image Guided
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