Cutaneous Angiosarcoma of the Breast

2021 ◽  
Author(s):  
Ines Alonso ◽  
Olatz Gorrino Angulo, MD ◽  
Monica Santamaria, MD
2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Yoko Suzuki ◽  
Kohei Taniguchi ◽  
Minami Hatono ◽  
Yukiko Kajiwara ◽  
Yuko Abe ◽  
...  

Cancers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 3911
Author(s):  
Markus Notter ◽  
Emanuel Stutz ◽  
Andreas R. Thomsen ◽  
Peter Vaupel

Background: Radiation-associated angiosarcoma of the breast (RAASB) is a rare, challenging disease, with surgery being the accepted basic therapeutic approach. In contrast, the role of adjuvant and systemic therapies is a subject of some controversy. Local recurrence rates reported in the literature are mostly heterogeneous and are highly dependent on the extent of surgery. In cases of locally recurrent or unresectable RAASB, prognosis is very poor. Methods: We retrospectively report on 10 consecutive RAASB patients, most of them presenting with locally recurrent or unresectable RAASB, which were treated with thermography-controlled water-filtered infrared-A (wIRA) superficial hyperthermia (HT) immediately followed by re-irradiation (re-RT). Patients with RAASB were graded based on their tumor extent before onset of radiotherapy (RT). Results: We recorded a local control (LC) rate dependent on tumor extent ranging from a high LC rate of 100% (two of two patients) in the adjuvant setting with an R0 or R2 resection to a limited LC rate of 33% (one of three patients) in patients with inoperable, macroscopic tumor lesions. Conclusion: Combined HT and re-RT should be considered as an option (a) for adjuvant treatment of RAASB, especially in cases with positive resection margins and after surgery of local recurrence (LR), and (b) for definitive treatment of unresectable RAASB.


JAMA ◽  
1978 ◽  
Vol 240 (8) ◽  
pp. 737
Author(s):  
Geoffrey L. Smoron

2002 ◽  
Vol 127 (5) ◽  
pp. 388-391 ◽  
Author(s):  
G Anania ◽  
P.C Parodi ◽  
A Sanna ◽  
E Rampino ◽  
E Marcotti ◽  
...  

2013 ◽  
Vol 58 (2) ◽  
pp. 208-212 ◽  
Author(s):  
Ailbhe C O'Neill ◽  
Clare D'Arcy ◽  
Enda McDermott ◽  
Ann O'Doherty ◽  
Cecily Quinn ◽  
...  

2010 ◽  
Vol 17 (1) ◽  
Author(s):  
S. Muzumder ◽  
P. Das ◽  
M. Kumar ◽  
S. Bhasker ◽  
C. Sarkar ◽  
...  

2018 ◽  
Vol 51 (5) ◽  
pp. 281-286 ◽  
Author(s):  
Ines Alves ◽  
José Carlos Marques

Abstract Objective: To characterize a population of patients with radiation-induced angiosarcoma (RIAS) of the breast treated at an oncology center, focusing mainly on the imaging features, although also on the clinical presentation, diagnosis, and management. Materials and Methods: We performed a retrospective review of patients with histologically proven angiosarcoma of the breast or chest wall, all of whom received radiotherapy, after conservative or radical breast surgery, between 2000 and 2015. Results: Eleven patients met the inclusion criteria. The median age at the time of diagnosis of RIAS of the breast was 71.5 years (range, 58-87 years), and the median latency period was 8.9 years (range, 4-27 years). The rate of local recurrence was 54.4%, RIAS recurring after a median period of 10 months (range, 3-18 months), and distant metastases occurred in three patients (27.3%). All of the tumors were accompanied by skin changes, and a palpable mass was seen in four. Most of the imaging findings were nonspecific. Six patients underwent magnetic resonance imaging, which revealed pronounced skin enhancement in all six. Ultrasound-guided core needle biopsies were negative in three of the eight patients. Conclusion: RIAS of the breast is a rare but recognized complication of radiotherapy for breast carcinoma, with a poor prognosis and high recurrence rate, which requires a high index of suspicion for a prompt diagnosis.


2018 ◽  
Vol 25 (1) ◽  
pp. 50 ◽  
Author(s):  
M. Kunkiel ◽  
M. Maczkiewicz ◽  
A. Jagiello-Gruszfeld ◽  
Z. Nowecki

Angiosarcomas of the breast are rare parenchymal malignancies of the chest wall. Surgery is the main treatment modality with chemotherapy and radiotherapy used in case of recurrence. With generally unfavourable prognosis and lack of clear treatment guidelines due to its rarity and scarcity of available data, angiosarcoma of the breast is a challenging clinical situation for both oncologist and patient. We present here the results of a series of 11 consecutive primary angiosarcoma cases treated at our institute between 2000 and 2015.


1994 ◽  
Vol 12 (2) ◽  
pp. 145-155 ◽  
Author(s):  
Lewis R. Silverman ◽  
Liane Deligdisch ◽  
John Mandeli ◽  
Ezra M. Greenspan

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