Balò’s Concentric Sclerosis (BCS)

2021 ◽  
Author(s):  
Juan Carlos Vera ◽  
Bronwyn E. Hamilton, MD ◽  
Jacob Ormsby, MD, MBA ◽  
Diane Sun
2021 ◽  
Vol 14 ◽  
pp. 117954762198967
Author(s):  
Van Trung Hoang ◽  
Cong Thao Trinh ◽  
Hoang Anh Thi Van ◽  
Thanh Tam Thi Nguyen ◽  
Vichit Chansomphou ◽  
...  

Balo’s concentric sclerosis (BCS) is a rare demyelinating disease known as Multiple Sclerosis (MS) lesion type III. It is a disease of the white matter of the brain characterized by a round lesion with variable concentric myelinated and demyelinated layers, appearing as “onion bulb.” We present a case of BCS and discuss the imaging findings and management strategies of this disease. A 26-y-old male developed headache, weakness, and numbness of limbs. Magnetic resonance imaging (MRI) showed concentric lamellar like demyelinating lesions at the subcortical regions. The patient’s neurological symptoms were consistent with the MRI findings.


2021 ◽  
pp. 102602
Author(s):  
Hector R. Martinez ◽  
Irving Christian Rodriguez-Gonzalez ◽  
Juan M. Escamilla-Garza ◽  
Jose A. Figueroa-Sanchez ◽  
Axel Cruz Garcia-Aleman ◽  
...  

2017 ◽  
Vol 08 (S 01) ◽  
pp. S136-S138
Author(s):  
Sanjeev Kumar Bhoi ◽  
Suprava Naik ◽  
Jayantee Kalita ◽  
U. K. Misra

ABSTRACTBalo's concentric sclerosis (BCS) is a rare demyelinating lesion considered to be a variant of multiple sclerosis (MS). On magnetic resonance imaging (MRI) Balo's concentric sclerosis shows the typical concentric pattern. We report a case of 10 year old child with BCS who presented as post infectious acute disseminated encephalomyelitis (ADEM). He is asymptomatic and had no relapse after 6 years of follow-up.


2020 ◽  
Vol 8 ◽  
pp. 2050313X2094053 ◽  
Author(s):  
Daniela Grasso ◽  
Carmela Borreggine ◽  
Giulia Castorani ◽  
Doriana Vergara ◽  
Lucia Maria Cecilia Dimitri ◽  
...  

Baló’s concentric sclerosis is a rare variant of multiple sclerosis. It belongs to the group of primary inflammatory central nervous system demyelinating diseases having no clear etiology. Peculiar radiological findings on magnetic resonance imaging are alternating rings of demyelinated and myelinated axons resembling an “onion bulb.” We report on a case of a patient with cocaine abuse who presented with Balò’s-like acute multifocal leukoencephalopathy supported by histological and radiological findings. The abuse of cocaine and its most frequent adulterant, levamisole, may induce ischemic or hemorrhagic stroke and metabolic or multifocal inflammatory leukoencephalopathy. Only a few studies described levamisole-induced leukoencephalopathy mimicking Balò round lesions. Nevertheless, it has not yet been established the correlation between them; it might also be possible that the cocaine/levamisole addiction represents just a coincidence in some of those patients affected by Balò sclerosis disease.


2020 ◽  
Vol 42 ◽  
pp. 102078 ◽  
Author(s):  
Xavier Ayrignac ◽  
Laurent Letourneau-Guillon ◽  
Clarisse Carra-Dallière ◽  
Pierre Duquette ◽  
Marc Girard ◽  
...  

2013 ◽  
Vol 2013 (jan25 1) ◽  
pp. bcr2012008413-bcr2012008413 ◽  
Author(s):  
P. Ripellino ◽  
A. Stecco ◽  
M. A. Leone ◽  
R. Cantello

2018 ◽  
Vol 29 (8) ◽  
pp. 873-882 ◽  
Author(s):  
Ali Amini Harandi ◽  
Akram Esfandani ◽  
Hossein Pakdaman ◽  
Mehdi Abbasi ◽  
Mohammad Ali Sahraian

Abstract Balo’s concentric sclerosis (BCS) is considered a variant of multiple sclerosis characterized by concentric lamella of alternating demyelinated and partially myelinated tissues. It is a rare and a relatively acute condition. Attacks may proceed rapidly over weeks or months, typically without remission, like Marburg’s variant, resulting in death or severe disability. However, the majority of cases have a more benign, self-limiting course with spontaneous remission. Magnetic resonance imaging is a primary imaging modality in the diagnosis of BCS. Treatment with intense immunosuppression may be indicated in patients with more aggressive form. New reports reveal more evidence regarding the pathophysiology and treatment strategies.


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