This discussion was moderated by James P. Maloney, MD, Associate Professor, Division of Pulmonary Science and Critical Care Medicine, University of Colorado, Denver, Colorado. The participants included Robert P. Frantz, MD, Assistant Professor of Medicine, Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota; Michael A. Mathier, MD, Assistant Professor of Medicine, Director, Pulmonary Hypertension Program, and Associate Director, Cardiovascular Fellowship Program, University of Pittsburgh, Pittsburgh, Pennsylvania; and James B. Young, MD, Professor and Chairman, Division of Medicine, and George and Linda Kaufman Chair, Cleveland Clinic Foundation, Cleveland, Ohio.