Experimental Brain Abscess Evolution: Computed Tomographic and Neuropathologic Correlation

Radiology ◽  
1979 ◽  
Vol 133 (1) ◽  
pp. 113-122 ◽  
Author(s):  
Dieter R. Enzmann ◽  
Richard H. Britt ◽  
Anne S. Yeager
Keyword(s):  
Brain Abscess ◽  
Computed Tomographic ◽  
Experimental Brain Abscess

Short term, high dose corticosteroids in computed tomographic staging of experimental brain abscess

1982 ◽  
Vol 23 (5) ◽  
pp. 279-284 ◽  
Author(s):  
B. E. Lyons ◽  
D. R. Enzmann ◽  
R. H. Britt ◽  
W. G. Obana ◽  
R. C. Placone ◽  
...  
Keyword(s):  
Brain Abscess ◽  
High Dose ◽  
Short Term ◽  
Computed Tomographic ◽  
Experimental Brain Abscess

NMR AND CT CORRELATION IN EXPERIMENTAL BRAIN ABSCESS

1983 ◽  
Vol 7 (1) ◽  
pp. 182 ◽  
Author(s):  
Michael Brant-Zawadzki ◽  
Dieter R. Enzmann ◽  
Richard H. Britt ◽  
Phil Sheldon
Keyword(s):  
Brain Abscess ◽  
Experimental Brain Abscess

OUTCOME OF BRAIN ABSCESS BY CLOSTRIDIUM PERFRINGENS

Neurosurgery ◽  
2007 ◽  
Vol 61 (6) ◽  
pp. E1339-E1339 ◽  
Author(s):  
Chaim B. Colen ◽  
Mahmoud Rayes ◽  
Setti Rengachary ◽  
Murali Guthikonda
Keyword(s):  
Brain Abscess ◽  
Clostridium Perfringens ◽  
Soft Tissues ◽  
Severe Infection ◽  
Surgical Excision ◽  
Penicillin G ◽  
Necrotic Tissue ◽  
Excellent Outcome ◽  
Computed Tomographic ◽  
Antibiotic Coverage

Abstract OBJECTIVE Despite the aggressive infection of soft tissue caused by Clostridium perfringens (gas gangrene-necrotizing fasciitis), a brain abscess with this bacteria treated by early surgical excision, debridement of necrotic tissue, and antibiotic coverage may be expected to have a good recovery. Long-term follow-up has not been well established in this group of patients. We report this case to show the outcome at 3 years post surgical and antibiotic treatment for C. perfringens brain abscess and stress the need for urgent intervention to achieve good outcome. We also present a literature review of Clostridial brain abscesses since the 1960s. CLINICAL PRESENTATION A 53-year-old man was brought to the emergency room after having a witnessed seizure status postassault 3 days before admission. On presentation, he was febrile, disoriented, lethargic, and demonstrated right upper extremity weakness. A computed tomographic scan of the head showed a left frontoparietal depressed cranial fracture complicated with gas and intraparenchymal air fluid level cavity. INTERVENTION Emergent surgery for debridement and excision of necrotic tissue was performed. Empiric intravenous antibiotic therapy was started and penicillin G was added for 6 weeks after C. perfringens was demonstrated. CONCLUSION Despite the severe infection and effect of C. perfringens in soft tissues in the brain, it appears that emergent surgical debridement and antibiotic coverage will yield an excellent outcome for these patients.

scholarly journals Evaluation of capsular and acapsular strains of S. aureus in an experimental brain abscess model

2010 ◽  
Vol 218 (1-2) ◽  
pp. 83-93 ◽  
Author(s):  
Nilufer Esen ◽  
Gail Wagoner ◽  
Napoleon Philips
Keyword(s):  
Brain Abscess ◽  
Experimental Brain Abscess

Production of experimental brain abscess in the rat

1979 ◽  
Vol 51 (5) ◽  
pp. 685-690 ◽  
Author(s):  
H. Richard Winn ◽  
Michael Mendes ◽  
Paul Moore ◽  
Clarabelle Wheeler ◽  
George Rodeheaver
Keyword(s):  
Brain Abscess ◽  
Clinical Situation ◽  
Small Animals ◽  
Content Type ◽  
History Of ◽  
Slow Infusion ◽  
The Brain ◽  
Number Of Bacteria ◽  
Experimental Brain Abscess ◽  
Fine Print

✓ Experimental evaluation of brain abscess has been inhibited by the lack of a simple and reproducible model in small animals. A stereotaxic headholder and slow infusion of 1 µl of saline, containing a known number of bacteria, were used to produce brain abscess consistently in the rat. The natural history of the brain abscess produced by this technique closely simulated that found in the human clinical situation.

Treatment of experimental brain abscess

1989 ◽  
Vol 100 (1-2) ◽  
pp. 79-83 ◽  
Author(s):  
A. Paşaoğlu ◽  
A. Yildizhan ◽  
B. Kandemir
Keyword(s):  
Brain Abscess ◽  
Experimental Brain Abscess
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